Zobrazeno 1 - 10
of 25
pro vyhledávání: '"RNA methyltransferase activity"'
Publikováno v:
Plantcell physiology. 62(6)
Ribosomal RNA (rRNA) methylation is a pivotal process in the assembly and activity of ribosomes, which in turn play vital roles in the growth, development and stress responses of plants. Although few methyltransferases responsible for rRNA methylatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d223002b32bb03af3aaa98bde05031bd
https://pubmed.ncbi.nlm.nih.gov/34015128
https://pubmed.ncbi.nlm.nih.gov/34015128
Autor:
Erdem Sendinc, George S. Vassiliou, Yang Shi, Konstantinos Tzelepis, Gonçalo J. L. Bernardes, Hannah Kiely-Collins, Madoka E Hazemi, Sigitas Mikutis, Muxin Gu, Demetrios Aspris
Publikováno v:
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
ACS Central Science, Vol 6, Iss 12, Pp 2196-2208 (2020)
ACS Central Science
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
ACS Central Science, Vol 6, Iss 12, Pp 2196-2208 (2020)
ACS Central Science
© 2020 American Chemical Society. This is an open access article published under a Creative Commons Attribution (CC-BY) License, which permits unrestricted use, distribution and reproduction in any medium, provided the author and source are cited.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4712067cbb57e56d88e6f906f5727d6f
Publikováno v:
Journal of Hematology & Oncology
Journal of Hematology & Oncology, Vol 13, Iss 1, Pp 1-15 (2020)
Journal of Hematology & Oncology, Vol 13, Iss 1, Pp 1-15 (2020)
N6-methyladenosine (m6A) is the most abundant mRNA modification and is catalyzed by the methyltransferase complex, in which methyltransferase-like 3 (METTL3) is the sole catalytic subunit. Accumulating evidence in recent years reveals that METTL3 pla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fdca62c4ff836c01251214e8ac762be9
https://pubmed.ncbi.nlm.nih.gov/32854717
https://pubmed.ncbi.nlm.nih.gov/32854717
Autor:
Nakul M. Shah, Blerta Xhemalce, Sravan K. Devanathan, Samantha B. Shelton, Nathan S. Abell, Marvin Mercado
Publikováno v:
Cell Reports, Vol 22, Iss 6, Pp 1374-1383 (2018)
Summary: RNAP II switching from the paused to the productive transcription elongation state is a pivotal regulatory step that requires specific phosphorylations catalyzed by the P-TEFb kinase. Nucleosolic P-TEFb activity is inhibited by its interacti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb7857934c13fba205dd4596d78aaf2f
https://doi.org/10.1016/j.celrep.2018.01.028
https://doi.org/10.1016/j.celrep.2018.01.028
Autor:
Rong Deng, Jianfeng He, Jian Huang, Jianxiu Yu, Guo-Qiang Chen, Xian Zhao, Jinke Cheng, Yanming Guo, Lian Li, Ming Xu, Yanli Wang, Yuzhang Du, Bin Jiang, Jinzhuo Dou, Guofang Hou, Hailong Zhang, Ran Chen
Publikováno v:
Nucleic Acids Research
The methyltransferase like 3 (METTL3) is a key component of the large N6-adenosine-methyltransferase complex in mammalian responsible for N6-methyladenosine (m6A) modification in diverse RNAs including mRNA, tRNA, rRNA, small nuclear RNA, microRNA pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e95022b5cfdf5a8a541de59b89c43ef0
http://europepmc.org/articles/PMC6007514
http://europepmc.org/articles/PMC6007514
Autor:
Zhe Liang, Lisha Shen, Qian Zhang, Leah A. Vardy, Vonny I. Leo, Xuean Cui, Shengjie Bao, Bin Zhang, Xiaofeng Gu, Yuke Geng, Tiegang Lu, Hao Yu
Publikováno v:
Molecular Plant. 10:1387-1399
5-Methylcytosine (m5C) is a well-characterized DNA modification, and is also predominantly reported in abundant non-coding RNAs in both prokaryotes and eukaryotes. However, the distribution and biological functions of m5C in plant mRNAs remain largel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06814ceb5a7527a205f8e7eca2d87893
https://doi.org/10.1016/j.molp.2017.09.013
https://doi.org/10.1016/j.molp.2017.09.013
Autor:
Samantha B. Shelton, Blerta Xhemalce
Publikováno v:
Journal of Visualized Experiments.
There are more than 100 chemically distinct modifications of RNA, two thirds of which consist of methylations. Interest in RNA modifications, and especially methylations, has re-emerged due to the important roles played by the enzymes that write and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42ec5dcb03bba79bac6deb248f2a73f2
https://doi.org/10.3791/59856-v
https://doi.org/10.3791/59856-v
Autor:
Daniela Schulz, Andrea Rentmeister
Publikováno v:
RNA biology. 9(5)
Post-transcriptional modifications of RNA diversify the genetically encoded sequences and play important roles in fundamental cellular processes like mRNA and rRNA maturation. Most RNA methylations are catalyzed by S-adenosylmethionine-dependent RNA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebea9bdd96222bf3d03ef1240e35ff39
https://pubmed.ncbi.nlm.nih.gov/22614835
https://pubmed.ncbi.nlm.nih.gov/22614835
Autor:
Sha Mi, Victor Stollar
Publikováno v:
Virology. 184:423-427
We have constructed two plasmids, pSR5-42 and pSR5-Toto, which under lac control expressed the SVLM21 and the SVToto forms, respectively, of the Sindbis virus nonstructural protein, nsP1. The induced protein, which was the major protein made followin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39fe4e4f287f1bc06bdbd90e80ad92ad
https://doi.org/10.1016/0042-6822(91)90862-6
https://doi.org/10.1016/0042-6822(91)90862-6
Publikováno v:
International journal of biological macromolecules. 42(1)
CIAPIN1 is a newly identified anti-apoptosis molecule which plays an important role in definitive haematopoiesis in mouse fetal liver and confers multidrug resistance in gastric cancer cells. However, the biophysical function of CIAPIN1 is far from e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::904e5edb10ef55660c4bf845489f2a55
https://pubmed.ncbi.nlm.nih.gov/17935775
https://pubmed.ncbi.nlm.nih.gov/17935775