Zobrazeno 1 - 10
of 155
pro vyhledávání: '"RNA based therapeutics"'
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Externí odkaz:
https://doaj.org/article/a829c8c03fa1411d8f91e3033ab2abaa
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Externí odkaz:
https://doaj.org/article/db5f761666284d67a77dc722c38b51f8
Autor:
Mohammad Ahmad, Louis-Bastien Weiswald, Laurent Poulain, Christophe Denoyelle, Matthieu Meryet-Figuiere
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 42, Iss 1, Pp 1-14 (2023)
Abstract Cancer is the main cause of death worldwide and metastasis is a major cause of poor prognosis and cancer-associated mortality. Metastatic conversion of cancer cells is a multiplex process, including EMT through cytoskeleton remodeling and in
Externí odkaz:
https://doaj.org/article/1f4c2771b6a3420a838dd514d0c3ae53
Publikováno v:
RNA Biology, Vol 19, Iss 1, Pp 594-608 (2022)
RNA therapeutics comprise a diverse group of oligonucleotide-based drugs such as antisense oligonucleotides (ASOs), small interfering RNAs (siRNAs), and short hairpin RNAs (shRNAs) that can be designed to selectively interact with drug targets curren
Externí odkaz:
https://doaj.org/article/59b6bf0a675a472594fab016df0d96f8
Publikováno v:
Current Research in Biotechnology, Vol 6, Iss , Pp 100150- (2023)
The first RNA therapeutic molecule, Fomivirsen, was approved for a clinic in 1998 as an antisense oligonucleotide therapeutic. Twenty-four years later, we found that more than a dozen RNA therapeutics had received approval and entered the clinic. In
Externí odkaz:
https://doaj.org/article/1e88f883a54b4bd49a13a07c064c6d33
Publikováno v:
Neural Regeneration Research, Vol 17, Iss 10, Pp 2157-2165 (2022)
Injuries to the central nervous system (CNS) such as stroke, brain, and spinal cord trauma often result in permanent disabilities because adult CNS neurons only exhibit limited axon regeneration. The brain has a surprising intrinsic capability of rec
Externí odkaz:
https://doaj.org/article/37560992380146a9a0c83f42eedeb169
Autor:
Behdad Tahayori
Publikováno v:
Frontiers in Genetics, Vol 11 (2020)
Externí odkaz:
https://doaj.org/article/ec8edc58db404fb9ade9ecd8720b5635
Akademický článek
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Publikováno v:
Pharmaceutics, Vol 13, Iss 9, p 1397 (2021)
Dementia is described as the fifth leading cause of death worldwide and Alzheimer’s disease (AD) is recognized as the most common, causing a huge impact on health costs and quality of patients’ lives. The main hallmarks that are commonly associat
Externí odkaz:
https://doaj.org/article/0ae235ec460a43f68281b612541f5ead
Publikováno v:
Trends in Microbiology
In recent decades, RNA-based therapeutics have transitioned from a near impossibility to a compelling treatment alternative for genetic disorders and infectious diseases. The mRNA vaccines against severe acute respiratory syndrome coronavirus 2 (SARS