Zobrazeno 1 - 10
of 1 399
pro vyhledávání: '"RNA aptamer"'
Fluorogenic RNA aptamer based artificial membraneless organelles for small molecule and cell sensing
Autor:
Wang, Long a, 1, Ji, Ruoyang a, 1, Yan, Jingyi b, ⁎, Ma, Yijie a, Zhou, Shijia a, Chen, Houhe a, ⁎, Ren, Kewei a, c, ⁎
Publikováno v:
In Chemical Engineering Journal 1 November 2024 499
Autor:
Liu, Hao a, 1, Lv, Meng-Mei b, 1, Li, Xiang a, Su, Mei a, Nie, Yin-Gang a, Ying, Zhan-Ming a, ⁎
Publikováno v:
In Biosensors and Bioelectronics 15 March 2025 272
Autor:
Muhammad Faisal, Aditya P. Sarnaik, Nandini Kannoju, Nima Hajinajaf, Muhammad Javaid Asad, Ryan W. Davis, Arul M. Varman
Publikováno v:
Microbial Cell Factories, Vol 23, Iss 1, Pp 1-13 (2024)
Abstract Background Ribulose-1,5-bisphosphate carboxylase/oxygenase (RuBisCO) is the most abundant soluble protein in nature. Extensive studies have been conducted for improving its activity in photosynthesis through approaches like protein engineeri
Externí odkaz:
https://doaj.org/article/8d8e221318de49ac971d7f5487f5a65e
Autor:
Qian Hou, Samie R. Jaffrey
Publikováno v:
RNA Biology, Vol 20, Iss 1, Pp 198-206 (2023)
RNA aptamers are structured RNAs that can bind to diverse ligands, including proteins, metabolites, and other small molecules. RNA aptamers are widely used as in vitro affinity reagents. However, RNA aptamers have not been highly successful as bioact
Externí odkaz:
https://doaj.org/article/12a5e1b8b2a94a93b8388256b536cc86
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 33, Iss , Pp 559-571 (2023)
KRAS mutations are one of the most common oncogenic driver mutations in human cancers, including non-small cell lung cancer (NSCLC), and have established roles in cancer pathogenesis and therapeutic resistance. The development of effective inhibitors
Externí odkaz:
https://doaj.org/article/050890c080c3488f8b90fc7156db0162
Autor:
You-Cheng Liao, Tzu-Chun Cheng, Shih-Hsin Tu, Jungshan Chang, Peixuan Guo, Li-Ching Chen, Yuan-Soon Ho
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 33, Iss , Pp 351-366 (2023)
Triple-negative breast cancer (TNBC) is highly aggressive with a poor prognosis because of a lack of cell markers as drug targets. α9-Nicotinic acetylcholine receptor (nAChR) is expressed abundantly in TNBC; thus, it is a valuable biomarker for TNBC
Externí odkaz:
https://doaj.org/article/a18fa65abcf64390b5496800e762520a
Publikováno v:
Biosensors, Vol 14, Iss 7, p 350 (2024)
Aptamers are nucleic acid sequences that specifically bind with target molecules and are vital to applications such as biosensing, drug development, disease diagnostics, etc. The traditional selection procedure of aptamers is based on the Systematic
Externí odkaz:
https://doaj.org/article/1d35cd7505424b82b73658b5ea0efab4
Autor:
Muthusamy Sivakumar, Sangami Ervanan, Susithra Lakshmanan, Sathya Venkatesan, Takatoshi Kinoshita, Duraikkannu Shanthana Lakshmi, Alagarsamy Santhana Krishna Kumar
Publikováno v:
Micromachines, Vol 15, Iss 6, p 741 (2024)
In this paper, one of the great challenges faced by silicon-based biosensors is resolved using a biomaterial multilayer. Tiny biomolecules are deposited on silicon substrates, producing devices that have the ability to act as iridescent color sensors
Externí odkaz:
https://doaj.org/article/428ddfd72b1e44c297af1c84760eda80
Autor:
Tae Hyeong Kim, Seong-Wook Lee
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 31, Iss , Pp 101151- (2023)
Hepatitis C virus (HCV) infections frequently recur after liver transplantation in patients with HCV-related liver diseases. Approximately 30% of these patients progress to cirrhosis within 5 years after surgery. In this study, we proposed an effecti
Externí odkaz:
https://doaj.org/article/83cac53e924c4d3daba501d42e01995a
Autor:
Beilei Lei, Linda B. Liu, Lauren Stokes, Paloma H. Giangrande, Francis J. Miller, Jr., Saami K. Yazdani
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 34, Iss , Pp 102023- (2023)
The local delivery of antiproliferative agents to inhibit neointimal growth is not specific to vascular smooth muscle cells (VSMC) and delays reendothelialization and vascular healing. This investigation was intended to evaluate the effect of luminal
Externí odkaz:
https://doaj.org/article/45a81757d7534d55ac6af4b27abbb0b3