Functional suppression of a yeast maf1 deletion mutant by overdose of the N-terminal fragment of the largest RNA polymerase III subunit, C160.

Autor: Łopusińska A; Laboratory of tRNA Transcription, Institute of Biochemistry and Biophysics, Polish Academy of Sciences, Warsaw, Poland., Farhat M; Laboratory of tRNA Transcription, Institute of Biochemistry and Biophysics, Polish Academy of Sciences, Warsaw, Poland., Cieśla M; Laboratory of tRNA Transcription, Institute of Biochemistry and Biophysics, Polish Academy of Sciences, Warsaw, Poland. Electronic address: goges@ibb.waw.pl.

Publikováno v: Gene [Gene] 2024 Dec 20; Vol. 930, pp. 148839. Date of Electronic Publication: 2024 Aug 13.

Single-cell RNA sequencing of nc886, a non-coding RNA transcribed by RNA polymerase III, with a primer spike-in strategy.

Autor: Shin GJ; Department of Microbiology, The Catholic University of Korea, Seoul, Korea.; Department of Biomedicine and Health Sciences, The Catholic University of Korea, Seoul, Korea., Choi BH; Department of Cancer Biomedical Science, Graduate School of Cancer Science and Policy, National Cancer Center, Goyang, Korea., Eum HH; Department of Microbiology, The Catholic University of Korea, Seoul, Korea., Jo A; Department of Microbiology, The Catholic University of Korea, Seoul, Korea., Kim N; Department of Microbiology, The Catholic University of Korea, Seoul, Korea., Kang H; Department of Microbiology, The Catholic University of Korea, Seoul, Korea.; Department of Biomedicine and Health Sciences, The Catholic University of Korea, Seoul, Korea., Hong D; Department of Biomedicine and Health Sciences, The Catholic University of Korea, Seoul, Korea.; Department of Medical Informatics, The Catholic University of Korea, Seoul, Korea., Jang JJ; Department of Cancer Biomedical Science, Graduate School of Cancer Science and Policy, National Cancer Center, Goyang, Korea., Lee HH; Department of Cancer Biomedical Science, Graduate School of Cancer Science and Policy, National Cancer Center, Goyang, Korea., Lee YS; Division of Rare Cancer, Research Institute, National Cancer Center, Goyang, Korea., Lee YS; Department of Cancer Biomedical Science, Graduate School of Cancer Science and Policy, National Cancer Center, Goyang, Korea., Lee HO; Department of Microbiology, The Catholic University of Korea, Seoul, Korea.; Department of Biomedicine and Health Sciences, The Catholic University of Korea, Seoul, Korea.

Publikováno v: PloS one [PLoS One] 2024 Aug 27; Vol. 19 (8), pp. e0301562. Date of Electronic Publication: 2024 Aug 27 (Print Publication: 2024).

The choreography of chromatin in RNA polymerase III regulation.

Autor: van Breugel ME; Division of Gene Regulation, Netherlands Cancer Institute, Amsterdam 1066 CX, The Netherlands., Gerber A; Department of Neurosurgery, Amsterdam UMC Location Vrije Universiteit Amsterdam, Amsterdam 1081HV, The Netherlands.; Cancer Center Amsterdam, Cancer Biology, Amsterdam 1081HV, The Netherlands., van Leeuwen F; Division of Gene Regulation, Netherlands Cancer Institute, Amsterdam 1066 CX, The Netherlands.; Department of Medical Biology, Amsterdam UMC, University of Amsterdam, Amsterdam 1105 AZ, The Netherlands.

Publikováno v: Biochemical Society transactions [Biochem Soc Trans] 2024 Jun 26; Vol. 52 (3), pp. 1173-1189.

Biallelic variants in GTF3C5, a regulator of RNA polymerase III-mediated transcription, cause a multisystem developmental disorder.

Autor: Iwata-Otsubo A; Division of Human Genetics/Roberts Individualized Medical Genetics Center, Children's Hospital of Philadelphia, Philadelphia, PA, 19104, USA. aotsubo@med.umich.edu.; Department of Pathology, University of Michigan, 2800 Plymouth Rd, Ann Arbor, MI, 48109, USA. aotsubo@med.umich.edu., Skraban CM; Division of Human Genetics/Roberts Individualized Medical Genetics Center, Children's Hospital of Philadelphia, Philadelphia, PA, 19104, USA.; Department of Pediatrics, Perelman School of Medicine, The University of Pennsylvania, Philadelphia, PA, 19104, USA., Yoshimura A; Laboratory of Genome Structure and Function, Institute for Quantitative Biosciences, The University of Tokyo, Tokyo, 113-0032, Japan., Sakata T; Laboratory of Genome Structure and Function, Institute for Quantitative Biosciences, The University of Tokyo, Tokyo, 113-0032, Japan., Alves CAP; Department of Radiology, Children's Hospital of Philadelphia, Philadelphia, PA, 19104, USA., Fiordaliso SK; Division of Human Genetics/Roberts Individualized Medical Genetics Center, Children's Hospital of Philadelphia, Philadelphia, PA, 19104, USA., Kuroda Y; Division of Human Genetics/Roberts Individualized Medical Genetics Center, Children's Hospital of Philadelphia, Philadelphia, PA, 19104, USA., Vengoechea J; Department of Human Genetics, Emory University, Atlanta, GA, 30322, USA., Grochowsky A; Department of Pediatrics, Vanderbilt University Medical Center, Nashville, TN, 37232, USA., Ernste P; Department of Pediatrics, Vanderbilt University Medical Center, Nashville, TN, 37232, USA.; Invitae, San Francisco, CA, 94103, USA., Lulis L; Division of Genomic Diagnostics, Children's Hospital of Philadelphia, Philadelphia, PA, 19104, USA., Nesbitt A; Division of Genomic Diagnostics, Children's Hospital of Philadelphia, Philadelphia, PA, 19104, USA.; Veritas Genetics, Danvers, MA, 01923, USA., Tayoun AA; Division of Genomic Diagnostics, Children's Hospital of Philadelphia, Philadelphia, PA, 19104, USA.; Genomics Center of Excellence, Al Jalila Children's Specialty Hospital, Dubai Health, Center for Genomic Discovery, Mohammed Bin Rashid University, Dubai Health, UAE., Gray C; Division of Human Genetics/Roberts Individualized Medical Genetics Center, Children's Hospital of Philadelphia, Philadelphia, PA, 19104, USA., Towne MC; Ambry Genetics, Aliso Viejo, CA, 92656, USA., Radtke K; Ambry Genetics, Aliso Viejo, CA, 92656, USA., Normand EA; GeneDx, Gaithersburg, MD, 20877, USA., Rhodes L; GeneDx, Gaithersburg, MD, 20877, USA., Seiler C; Zebrafish Core, The Children's Hospital of Philadelphia, Philadelphia, PA, 19104, USA., Shirahige K; Laboratory of Genome Structure and Function, Institute for Quantitative Biosciences, The University of Tokyo, Tokyo, 113-0032, Japan., Izumi K; Division of Human Genetics/Roberts Individualized Medical Genetics Center, Children's Hospital of Philadelphia, Philadelphia, PA, 19104, USA. Kosuke.Izumi@UTsouthwestern.edu.; Department of Pediatrics, Perelman School of Medicine, The University of Pennsylvania, Philadelphia, PA, 19104, USA. Kosuke.Izumi@UTsouthwestern.edu.; Laboratory of Rare Disease Research, Institute for Quantitative Biosciences, The University of Tokyo, Tokyo, 113-0032, Japan. Kosuke.Izumi@UTsouthwestern.edu.; Division of Genetics and Metabolism, Department of Pediatrics, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd., Dallas, TX, 75390-8573, USA. Kosuke.Izumi@UTsouthwestern.edu.

Publikováno v: Human genetics [Hum Genet] 2024 Mar; Vol. 143 (3), pp. 437-453. Date of Electronic Publication: 2024 Mar 23.

Role of RNA polymerase III transcription and regulation in ischaemic stroke

Autor: Chi Kwan Tsang, X.F. Steven Zheng

Publikováno v: RNA Biology, Vol 21, Iss 1, Pp 1-10 (2024)

Ischaemic stroke is a leading cause of death and life-long disability due to neuronal cell death resulting from interruption of glucose and oxygen supplies. RNA polymerase III (Pol III)-dependent transcription plays a central role in protein synthesi

Externí odkaz: https://doaj.org/article/7bd1fca3d4a6429daf5dd082153a0184