Zobrazeno 1 - 10
of 455
pro vyhledávání: '"RNA Conformation"'
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 2003 Nov . 100(24), 13904-13909.
Externí odkaz:
https://www.jstor.org/stable/3148885
Akademický článek
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Publikováno v:
The Journal of Physical Chemistry. B
Understanding the dynamics of the SARS CoV-2 RNA genome and its dependence on temperature is necessary to fight the current COVID-19 crisis. Computationally, the handling of large data is a major challenge in the elucidation of the structures of RNA.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::172b44f6863ea92faef556c1f69927e5
https://doi.org/10.1021/acs.jpcb.1c05795
https://doi.org/10.1021/acs.jpcb.1c05795
Publikováno v:
J Phys Chem B
Accurate prediction of RNA structure and folding stability has a far-reaching impact on our understanding of RNA functions. Here we develop Vfold2D-MC, a new physics-based model, to predict RNA structure and folding thermodynamics from the sequence.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1585e3d0bded312b2cad2325bd218131
https://doi.org/10.1021/acs.jpcb.1c04731
https://doi.org/10.1021/acs.jpcb.1c04731
Autor:
Stella M. Lai, Vicki H. Wysocki, Ila A Marathe, Walter J. Zahurancik, Michael G. Poirier, Venkat Gopalan
Publikováno v:
Nucleic Acids Research
The ribonucleoprotein (RNP) form of archaeal RNase P comprises one catalytic RNA and five protein cofactors. To catalyze Mg2+-dependent cleavage of the 5′ leader from pre-tRNAs, the catalytic (C) and specificity (S) domains of the RNase P RNA (RPR)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d8f6ee716051189ffbcca751e329eeb
https://doi.org/10.1093/nar/gkab655
https://doi.org/10.1093/nar/gkab655
Autor:
Scott A. Showalter, Lois Pollack, Suzette A. Pabit, Erik C. Cook, Emery T. Usher, Yen-Lin Chen
Publikováno v:
Biophys J
Although conformational dynamics of RNA molecules are potentially important in microRNA (miRNA) processing, the role of the protein binding partners in facilitating the requisite structural changes is not well understood. In previous work, we and oth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c754a63a389997d69c303afdca44b1f8
https://doi.org/10.1016/j.bpj.2020.10.038
https://doi.org/10.1016/j.bpj.2020.10.038
Publikováno v:
Genes and Diseases, Vol 7, Iss 4, Pp 585-597 (2020)
Genes & Diseases
Genes & Diseases
N6-methyladenosine (m6A) is the most abundant inner RNA modification in eukaryotes. Due to the development of RNA sequencing technology, the distribution pattern of m6A in the transcriptome has been uncovered. Dynamically, the reversible N6-methylati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68374b8586162005f43ca7f2e4e3699f
https://doi.org/10.1016/j.gendis.2020.06.011
https://doi.org/10.1016/j.gendis.2020.06.011
Publikováno v:
Annu Rev Genet
Recent advances in pseudouridine detection reveal a complex pseudouridine landscape that includes messenger RNA and diverse classes of noncoding RNA in human cells. The known molecular functions of pseudouridine, which include stabilizing RNA conform
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5714b8168673a0cddae2f9df51d2c02
https://doi.org/10.1146/annurev-genet-112618-043830
https://doi.org/10.1146/annurev-genet-112618-043830
Publikováno v:
J Chem Theory Comput
The ability to accurately predict the binding site, binding pose, and binding affinity for ligand-RNA binding is important for RNA-targeted drug design. Here, we describe a new computational method, RLDOCK, for predicting the binding site and binding
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c945601001e03ef32a58c56159b6b2b7
https://doi.org/10.1021/acs.jctc.0c00798
https://doi.org/10.1021/acs.jctc.0c00798
Autor:
Ronald Swanstrom, Trinity Zang, Daniel R. Kuritzkes, Athe M. N. Tsibris, Phillip J. Tomezsko, Anthony T. Papenfuss, Ann Emery, Matthew D. Edwards, Tammy C. T. Lan, Paromita Gupta, Harish Swaminathan, Paul D. Bieniasz, Sitara Persad, Lachlan McIntosh, Vincent Corbin, Silvi Rouskin, Margalit Glasgow
Publikováno v:
Nature
Human immunodeficiency virus 1 (HIV-1) is a retrovirus with a ten-kilobase single-stranded RNA genome. HIV-1 must express all of its gene products from a single primary transcript, which undergoes alternative splicing to produce diverse protein produ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ada02574b201f96085c349314b09362f
http://europepmc.org/articles/PMC7310298
http://europepmc.org/articles/PMC7310298