Zobrazeno 1 - 10
of 25
pro vyhledávání: '"RNA, Untranslated/genetics"'
Autor:
William P. Schreiner, Jacob M. Garrigues, Jerry S. Chen, Amy E. Pasquinelli, Delaney C Pagliuso, Antti P. Aalto
Publikováno v:
Schreiner, W P, Pagliuso, D C, Garrigues, J M, Chen, J S, Aalto, A P & Pasquinelli, A E 2019, ' Remodeling of the Caenorhabditis elegans non-coding RNA transcriptome by heat shock ', Nucleic Acids Research, vol. 47, no. 18, pp. 9829-9841 . https://doi.org/10.1093/nar/gkz693
Nucleic Acids Research
Nucleic Acids Research
Elevated temperatures activate a heat shock response (HSR) to protect cells from the pathological effects of protein mis-folding, cellular mis-organization, organelle dysfunction and altered membrane fluidity. This response includes activation of the
Autor:
Daniela Delneri, Soukaina Timouma, Marcin G. Fraczek, Raymond T. O'Keefe, Catherine B. Millar, Steven Parker, Ping Wang, Laura Natalia Balarezo-Cisneros
Publikováno v:
Balarezo-Cisneros, L N, Parker, S, Fraczek, M G, Timouma, S, Wang, P, O'Keefe, R T, Millar, C B & Delneri, D 2021, ' Functional and transcriptional profiling of non-coding RNAs in yeast reveal context-dependent phenotypes and in trans effects on the protein regulatory network ', PLoS Genetics, vol. 17, no. 1, e1008761 . https://doi.org/10.1371/journal.pgen.1008761
PLoS Genetics
PLoS Genetics, Vol 17, Iss 1, p e1008761 (2021)
PLoS Genetics
PLoS Genetics, Vol 17, Iss 1, p e1008761 (2021)
Non-coding RNAs (ncRNAs), including the more recently identified Stable Unannotated Transcripts (SUTs) and Cryptic Unstable Transcripts (CUTs), are increasingly being shown to play pivotal roles in the transcriptional and post-transcriptional regulat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5229b68a60ccbb802158bf2ff091d9f2
https://www.research.manchester.ac.uk/portal/en/publications/functional-and-transcriptional-profiling-of-noncoding-rnas-in-yeast-reveal-contextdependent-phenotypes-and-in-trans-effects-on-the-protein-regulatory-network(8b9cfaa5-7364-41ad-beaa-a805b5d78d30).html
https://www.research.manchester.ac.uk/portal/en/publications/functional-and-transcriptional-profiling-of-noncoding-rnas-in-yeast-reveal-contextdependent-phenotypes-and-in-trans-effects-on-the-protein-regulatory-network(8b9cfaa5-7364-41ad-beaa-a805b5d78d30).html
Autor:
Claudiane Guay, Adriana Rodriguez-Trejo, Cécile Jacovetti, Romano Regazzi, Kejing Wu, Mustafa Bilal Bayazit, Flora Brozzi
Publikováno v:
Comprehensive Physiology
Comprehensive Physiology, vol. 10, no. 3, pp. 893-932
Comprehensive Physiology, vol. 10, no. 3, pp. 893-932
The discovery that most mammalian genome sequences are transcribed to ribonucleic acids (RNA) has revolutionized our understanding of the mechanisms governing key cellular processes and of the causes of human diseases, including diabetes mellitus. Pa
Autor:
Emma C. Teeling, Michael Hiller, Angelique Corthals, Aris Katzourakis, Graham M. Hughes, Dina K. N. Dechmann, Roger D. Ransome, Ksenia Lavrichenko, Lars S. Jermiin, Bogdan M. Kirilenko, Emilia C. Skirmuntt, Sylke Winkler, Martin Pippel, David A. Ray, Sébastien J. Puechmaille, Megan L. Power, Olivier Fedrigo, Gareth Jones, Liliana M. Dávalos, Sonja C. Vernes, Kevin A.M. Sullivan, Erich D. Jarvis, Lucy Burkitt-Gray, Zixia Huang, Juliana G. Roscito, Paolo Devanna, David Jebb, Andrea G. Locatelli, Eugene W. Myers
Publikováno v:
Nature
Jebb, D, Jones, G, Teeling, E C & al., E 2020, ' Six reference-quality genomes reveal evolution of bat adaptations ', Nature, vol. 583, pp. 578-584 . https://doi.org/10.1038/s41586-020-2486-3
Jebb, D, Jones, G, Teeling, E C & al., E 2020, ' Six reference-quality genomes reveal evolution of bat adaptations ', Nature, vol. 583, pp. 578-584 . https://doi.org/10.1038/s41586-020-2486-3
Bats possess extraordinary adaptations, including flight, echolocation, extreme longevity and unique immunity. High-quality genomes are crucial for understanding the molecular basis and evolution of these traits. Here we incorporated long-read sequen
Autor:
Peter Mirtschink, Rahul Sharma, Geetha Rossi, Sanjay Khadayate, Corinne Berthonneche, Eman Hagag, Wilhelm Krek, Corinne Bischof, Jaya Krishnan, Thierry Pedrazzini, Samuel Sossalla, Phillip Grote, Shuyang Traub, Niklaus Fankhauser, Alexandre Sarre, Sebastian Stehr, Stefanie Dimmeler, Minh Duc Pham
Publikováno v:
Circulation, vol. 139, no. 24, pp. 2778-2792
Circulation
Circulation, 139 (24)
Circulation
Circulation, 139 (24)
Supplemental Digital Content is available in the text.
Background: Enhancers are genomic regulatory elements conferring spatiotemporal and signal-dependent control of gene expression. Recent evidence suggests that enhancers can generate noncodin
Background: Enhancers are genomic regulatory elements conferring spatiotemporal and signal-dependent control of gene expression. Recent evidence suggests that enhancers can generate noncodin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6d25d4a747aa8a59989af7a0718498f
https://serval.unil.ch/resource/serval:BIB_BAE7C7F2C66F.P001/REF.pdf
https://serval.unil.ch/resource/serval:BIB_BAE7C7F2C66F.P001/REF.pdf
Autor:
Shu-Yun Le, Zhi-Ming Zheng, Vladimir Majerciak, David J. Liewehr, Maria J. Massimelli, Jeong-Gu Kang, Seth M. Steinberg
Publikováno v:
International Journal of Biological Sciences
International journal of biological sciences, vol 7, iss 8
International Journal of Biological Sciences, 7(8), 1145-60. Ivyspring International Publisher
International journal of biological sciences, vol 7, iss 8
International Journal of Biological Sciences, 7(8), 1145-60. Ivyspring International Publisher
Kaposi sarcoma-associated herpesvirus (KSHV) ORF57, also known as Mta (mRNA transcript accumulation), enhances viral intron-less transcript accumulation and promotes splicing of intron-containing viral RNA transcripts. In this study, we identified KS
Autor:
Pedrazzini, T.
Publikováno v:
Médecine Sciences : M/s, vol. 31, no. 3, pp. 261-267
The identification and characterization of long noncoding RNA in a variety of tissues represent major achievements that contribute to our understanding of the molecular mechanisms controlling gene expression. In particular, long noncoding RNA play cr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______1900::9cbbf1a7d2797b6744a8330d3135c5d1
https://serval.unil.ch/notice/serval:BIB_B2CD2BE286E3
https://serval.unil.ch/notice/serval:BIB_B2CD2BE286E3
Autor:
Stylianos E. Antonarakis, C. Victor Jongeneel, Samuel Deutsch, Volker Flegel, Philipp Bucher, Nathalie Scamuffa, Brian Stevenson, Emmanouil T. Dermitzakis, Catherine Ucla, Robert Lyle, Alexandre Reymond
Publikováno v:
Nature, Vol. 420, No 6915 (2002) pp. 578-582
The use of comparative genomics to infer genome function relies on the understanding of how different components of the genome change over evolutionary time. The aim of such comparative analysis is to identify conserved, functionally transcribed sequ
Autor:
Mizielinska, Sarah, Isaacs, Adrian M.
Publikováno v:
Mizielinska, S & Isaacs, A M 2014, ' C9orf72 amyotrophic lateral sclerosis and frontotemporal dementia : gain or loss of function? ', Current Opinion in Neurology, vol. 27, no. 5, pp. 515-23 . https://doi.org/10.1097/WCO.0000000000000130
Current Opinion in Neurology
Current Opinion in Neurology
PURPOSE OF REVIEW: The molecular mechanisms that underlie chromosome 9 open reading frame 72 (C9orf72)-associated amyotrophic lateral sclerosis and frontotemporal dementia are rapidly emerging. Two potential disease mechanisms have been postulated -
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::ec25303fb82f712bee11b222055be5cb
https://kclpure.kcl.ac.uk/ws/files/122368921/C9orf72_amyotrophic_lateral_sclerosis_MIZIELINSKA_PubOct2014_GOLD_VoR_CC_BY_.pdf
https://kclpure.kcl.ac.uk/ws/files/122368921/C9orf72_amyotrophic_lateral_sclerosis_MIZIELINSKA_PubOct2014_GOLD_VoR_CC_BY_.pdf
Autor:
Claudio Forcato, Claudio Bonghi, Rosanna Zimbello, Michela D'Angelo, Massimiliano Corso, Alessandro Vannozzi, Margherita Lucchin, Nicola Vitulo, Giorgio Valle, Davide Campagna, Andrea Telatin, Elisa Corteggiani Carpinelli
Publikováno v:
BMC Plant Biology
BMC Plant Biology, BioMed Central, 2014, 14 (1), pp.99. ⟨10.1186/1471-2229-14-99⟩
BMC plant biology, 14
BMC Plant Biology, BioMed Central, 2014, 14 (1), pp.99. ⟨10.1186/1471-2229-14-99⟩
BMC plant biology, 14
Alternative splicing (AS) significantly enhances transcriptome complexity. It is differentially regulated in a wide variety of cell types and plays a role in several cellular processes. Here we describe a detailed survey of alternative splicing in gr