Výsledky vyhledávání - "RNA, Bacterial/metabolism"

RISK6, a 6-gene transcriptomic signature of TB disease risk, diagnosis and treatment response

Autor: Penn-Nicholson, A, Mbandi, SK, Thompson, E, Mendelsohn, SC, Suliman, S, Chegou, NN, Malherbe, ST, Darboe, F, Erasmus, M, Hanekom, WA, Bilek, N, Fisher, M, Kaufmann, SHE, Winter, J, Murphy, M, Wood, R, Morrow, C, Van Rhijn, I, Moody, B, Murray, M, Andrade, BB, Sterling, TR, Sutherland, J, Naidoo, K, Padayatchi, N, Walzl, G, Hatherill, M, Zak, D, Scriba, TJ, Kafaar, F, Workman, L, Mulenga, H, Hughes, EJ, Xasa, O, Veldsman, A, Cloete, Y, Abrahams, D, Moyo, S, Gelderbloem, S, Tameris, M, Geldenhuys, H, Ehrlich, R, Verver, S, Geiter, L, Black, GF, van der Spuy, G, Stanley, K, Kriel, M, Du Plessis, N, Nene, N, Roberts, T, Kleynhans, L, Gutschmidt, A, Smith, B, Loxton, AG, Tromp, G, Tabb, D, Ottenhoff, THM, Klein, MR, Haks, MC, Franken, KLMC, Geluk, A, van Meijgaarden, KE, Joosten, SA, Boom, WH, Thiel, B, Mayanja-Kizza, H, Joloba, M, Zalwango, S, Nsereko, M, Okwera, B, Kisingo, H, Parida, SK, Golinski, R, Maertzdorf, J, Weiner, J, Jacobson, M, Dockrell, H, Smith, S, Gorak-Stolinska, P, Hur, YG, Lalor, M, Lee, JS, Crampin, AC, French, N, Ngwira, B, Ben-Smith, A, Watkins, K, Ambrose, L, Simukonda, F, Mvula, H, Chilongo, F, Saul, J, Branson, K, Mahomed, H, Downing, K

Publikováno v: Scientific reports
Scientific reports, vol 10, iss 1
Scientific Reports
Scientific reports, 10(1):8629. Nature Publishing Group
Scientific Reports, Vol 10, Iss 1, Pp 1-21 (2020)
Scientific Reports, 10(1). NATURE PUBLISHING GROUP
Scientific Reports, 10(1). NLM (Medline)
Scientific Reports, 10(1):8629. Nature Publishing Group

Improved tuberculosis diagnostics and tools for monitoring treatment response are urgently needed. We developed a robust and simple, PCR-based host-blood transcriptomic signature, RISK6, for multiple applications: identifying individuals at risk of i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b72b4b335a138b78e75f4f968504b069
https://researchonline.lshtm.ac.uk/id/eprint/4656993/1/s41598-020-65043-8.pdf

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Deep genome annotation of the opportunistic human pathogen Streptococcus pneumoniae D39

Autor: Jelle Slager, Rieza Aprianto, Jan-Willem Veening

Publikováno v: Nucleic Acids Research, 46(19), 9971-9989. Oxford University Press
Nucleic Acids Research
Nucleic acids research, vol. 46, no. 19, pp. 9971-9989

A precise understanding of the genomic organization into transcriptional units and their regulation is essential for our comprehension of opportunistic human pathogens and how they cause disease. Using single-molecule real-time (PacBio) sequencing we

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ea4944069da1f72f1851aa32c32236a

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Small RNAs in major foodborne pathogens: from novel regulatory activities to future applications

Autor: Mette Thorsing, Birgitte H. Kallipolitis, Patricia Teixeira Dos Santos

Publikováno v: Thorsing, M, Santos, P I T D & Kallipolitis, B H 2018, ' Small RNAs in major foodborne pathogens : from novel regulatory activities to future applications ', Current Opinion in Biotechnology, vol. 49, pp. 120-128 . https://doi.org/10.1016/j.copbio.2017.08.006
Current Opinion in Biotechnology

Small regulatory RNAs (sRNAs) are involved in post-transcriptional control of important cellular processes and contribute to the success of a pathogen. Here, we use studies primarily selected from Salmonella enterica and Listeria monocytogenes to ill

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b8e530ae1363930d50803c49bb8ad65
https://pubmed.ncbi.nlm.nih.gov/28865341

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The structure of an E. coli tRNA f Met A 1-U 72 variant shows an unusual conformation of the A 1-U 72 base pair

Autor: Alexey Aleksandrov, Auriane Monestier, Pierre-Damien Coureux, Yves Mechulam, Emmanuelle Schmitt, Michel Panvert

Publikováno v: RNA
RNA, Cold Spring Harbor Laboratory Press, 2017, 23 (5), pp.673-682. ⟨10.1261/rna.057877.116⟩

Translation initiation in eukaryotes and archaea involves a methionylated initiator tRNA delivered to the ribosome in a ternary complex with e/aIF2 and GTP. Eukaryotic and archaeal initiator tRNAs contain a highly conserved A1–U72 base pair at the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ddc2c96f6476d95f0ed8cfac9e98107f
https://hal-polytechnique.archives-ouvertes.fr/hal-01961641/document

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Deep sequencing defines the transcriptional map ofL. pneumophilaand identifies growth phase-dependent regulated ncRNAs implicated in virulence

Autor: Odile Sismeiro, Carmen Buchrieser, Delphine Dervins-Ravault, Tobias Sahr, Christophe Rusniok, Jean-Yves Coppée

Publikováno v: RNA Biology
RNA Biology, 2012, 9 (4), pp.503-519. ⟨10.4161/rna.20270⟩
RNA Biology, Taylor & Francis, 2012, 9 (4), pp.503-519. ⟨10.4161/rna.20270⟩

International audience; The bacterium Legionella pneumophila is found ubiquitously in aquatic environments and can cause a severe pneumonia in humans called Legionnaires' disease. How this bacterium switches from intracellular to extracellular life a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ddc05d092ccdf3779cb5012957aa2da2
https://doi.org/10.4161/rna.20270

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Pleiotropic role of the RNA chaperone protein Hfq in the human pathogen Clostridium difficile

Autor: Olga Soutourina, Marc Monot, Bruno Dupuy, Isabelle Martin-Verstraete, Laure Saujet, Eliane Hajnsdorf, Pierre Boudry, Joël Caillet, Céline Gracia

Publikováno v: Journal of Bacteriology
Journal of Bacteriology, 2014, 196 (18), pp.3234-3248. ⟨10.1128/JB.01923-14⟩
Journal of Bacteriology, American Society for Microbiology, 2014, 196 (18), pp.3234-3248. ⟨10.1128/JB.01923-14⟩
Journal of Bacteriology, American Society for Microbiology, 2014, 196 (18), pp.3234-48. ⟨10.1128/JB.01923-14⟩

Clostridium difficile is an emergent human pathogen and the most common cause of nosocomial diarrhea. Our recent data strongly suggest the importance of RNA-based mechanisms for the control of gene expression in C. difficile . In an effort to underst

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8fbbd081bd82c114df38b363f02fad51
https://pubmed.ncbi.nlm.nih.gov/24982306

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Transcriptomic and metabolic responses of Staphylococcus aureus exposed to supra-physiological temperatures

Autor: Richard A. Proctor, Daniel Lew, Bénédicte Fleury, William L. Kelley, Friedrich Götz, Pierre Vaudaux

Publikováno v: BMC Microbiology, Vol. 9 (2009) P. 76
BMC Microbiology, Vol 9, Iss 1, p 76 (2009)
BMC Microbiology

Background Previous evaluation by different molecular and physiological assays of Staphylococcus aureus (S. aureus) responses to heat shock exposure yielded a still fragmentary view of the mechanisms determining bacterial survival or death at supra-p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c748c038ae77446bd2efe5a5735edcf
https://archive-ouverte.unige.ch/unige:9321

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