Immunological relationships of NGF, BDNF, and NT-3: recognition and functional inhibition by antibodies to NGF

Autor: RA Murphy, Robert S. Hodges, RF Alderson, Julie Haskins, Carl D. Richards, Vera Chlumecky, Ann Acheson, Philip A. Barker, RM Lindsay, E Reklow

Publikováno v: The Journal of Neuroscience. 13:2853-2862

Polyclonal antibodies raised against mouse 2.5S NGF (mNGF) and against synthetic peptides made from hydrophilic portions of mNGF have been used to compare the immunological properties of mNGF, human recombinant brain-derived neurotrophic factor (hrBD

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7aca069532ab0cbf8dc38707bbe681d
https://doi.org/10.1523/jneurosci.13-07-02853.1993

Engineering a long acting, non-biased relaxin agonist using Protein-in-Protein technology.

Autor: Agoulnik IU; Department of Human and Molecular Genetics, Herbert Wertheim College of Medicine, Florida International University, Miami, FL 33199, USA., Kaftanovskaya EM; Department of Human and Molecular Genetics, Herbert Wertheim College of Medicine, Florida International University, Miami, FL 33199, USA., Myhr C; Department of Human and Molecular Genetics, Herbert Wertheim College of Medicine, Florida International University, Miami, FL 33199, USA., Bathgate RAD; Florey Institute of Neuroscience and Mental Health, The University of Melbourne, Victoria 3010, Australia; Department of Biochemistry and Pharmacology, The University of Melbourne, Victoria 3010, Australia., Kocan M; Florey Institute of Neuroscience and Mental Health, The University of Melbourne, Victoria 3010, Australia., Peng Y; Scripps Research, 10550 N Torrey Pines Rd, La Jolla, CA 92037 USA., Lindsay RM; Zebra Biologics, Inc., 1041 Old Marlboro Road, Concord, MA 01742 USA., DiStefano PS; Zebra Biologics, Inc., 1041 Old Marlboro Road, Concord, MA 01742 USA. Electronic address: petedistefano88@gmail.com., Agoulnik AI; Department of Human and Molecular Genetics, Herbert Wertheim College of Medicine, Florida International University, Miami, FL 33199, USA. Electronic address: agoulniks@gmail.com.

Publikováno v: Biochemical pharmacology [Biochem Pharmacol] 2024 Sep; Vol. 227, pp. 116401. Date of Electronic Publication: 2024 Jun 28.

Selective activation and down-regulation of Trk receptors by neurotrophins in human neurons co-expressing TrkB and TrkC.

Autor: Ateaque S; School of Biosciences, Cardiff University, Cardiff, Wales, UK., Merkouris S; School of Biosciences, Cardiff University, Cardiff, Wales, UK., Wyatt S; School of Biosciences, Cardiff University, Cardiff, Wales, UK., Allen ND; School of Biosciences, Cardiff University, Cardiff, Wales, UK., Xie J; The Scripps Research Institute, La Jolla, California, USA., DiStefano PS; Zebra Biologics, Concord, Massachusetts, USA., Lindsay RM; Zebra Biologics, Concord, Massachusetts, USA., Barde YA; School of Biosciences, Cardiff University, Cardiff, Wales, UK.

Publikováno v: Journal of neurochemistry [J Neurochem] 2022 Jun; Vol. 161 (6), pp. 463-477. Date of Electronic Publication: 2022 May 10.

Using dalteparin in quotidian and nocturnal hemodialysis patients: A prospective study.

Autor: Huang SS; Department of Medicine, Division of Nephrology, Western University, London, Ontario, Canada.; Department of Medical Biophysics, Western University, London, Ontario, Canada.; Department of Paediatrics and Pathology and Laboratory Medicine, Western University, London, Ontario, Canada.; Kidney Clinical Research Unit, Lawson Research Institute, London, Ontario, Canada., Qi K; Department of Pharmacy, Western University, London, Ontario, Canada., Louzada M; Department of Medicine, Division of Hematology, Western University, London, Ontario, Canada., Lindsay RM; Department of Medicine, Division of Nephrology, Western University, London, Ontario, Canada.; Department of Medical Biophysics, Western University, London, Ontario, Canada.; Kidney Clinical Research Unit, Lawson Research Institute, London, Ontario, Canada., Rehman F; Department of Medicine, Division of Nephrology, Western University, London, Ontario, Canada.; Kidney Clinical Research Unit, Lawson Research Institute, London, Ontario, Canada., Ke H; Kidney Clinical Research Unit, Lawson Research Institute, London, Ontario, Canada., Muirhead N; Department of Medicine, Division of Nephrology, Western University, London, Ontario, Canada.

Publikováno v: Hemodialysis international. International Symposium on Home Hemodialysis [Hemodial Int] 2020 Apr; Vol. 24 (2), pp. 195-201. Date of Electronic Publication: 2019 Dec 05.

Fully human agonist antibodies to TrkB using autocrine cell-based selection from a combinatorial antibody library.

Autor: Merkouris S; School of Biosciences, Cardiff University, CF10 3AX Cardiff, United Kingdom., Barde YA; School of Biosciences, Cardiff University, CF10 3AX Cardiff, United Kingdom., Binley KE; School of Biosciences, Cardiff University, CF10 3AX Cardiff, United Kingdom., Allen ND; School of Biosciences, Cardiff University, CF10 3AX Cardiff, United Kingdom., Stepanov AV; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, 117997 Moscow, Russia., Wu NC; Department of Chemistry, The Scripps Research Institute, La Jolla, CA 92037., Grande G; Department of Chemistry, The Scripps Research Institute, La Jolla, CA 92037., Lin CW; Department of Chemistry, The Scripps Research Institute, La Jolla, CA 92037., Li M; School of Biosciences, Cardiff University, CF10 3AX Cardiff, United Kingdom., Nan X; School of Biosciences, Cardiff University, CF10 3AX Cardiff, United Kingdom., Chacon-Fernandez P; School of Biosciences, Cardiff University, CF10 3AX Cardiff, United Kingdom., DiStefano PS; Zebra Biologics, Concord, MA 01742., Lindsay RM; Zebra Biologics, Concord, MA 01742., Lerner RA; Department of Chemistry, The Scripps Research Institute, La Jolla, CA 92037; rlerner@scripps.edu jiaxie@scripps.edu., Xie J; Department of Chemistry, The Scripps Research Institute, La Jolla, CA 92037; rlerner@scripps.edu jiaxie@scripps.edu.

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2018 Jul 24; Vol. 115 (30), pp. E7023-E7032. Date of Electronic Publication: 2018 Jul 09.