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Cardiac complications associated with goal-directed therapy in high-risk surgical patients: a meta-analysis

Autor: N Arulkumaran, RM Grounds, Mark Hamilton, Andrew Rhodes, Jonathan Ball, Maurizio Cecconi, Carlos Corredor

Publikováno v: British Journal of Anaesthesia. 112:648-659

Patients with limited cardiopulmonary reserve are at risk of mortality and morbidity after major surgery. Augmentation of oxygen delivery index (DO2I) with i.v. fluids and inotropes (goal-directed therapy, GDT) has been shown to reduce postoperative

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df243c4f3c236e6f66addc4db55d3d13
https://doi.org/10.1093/bja/aet466

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Use of activated recombinant coagulation factor VII in patients undergoing reconstruction surgery for traumatic fracture of pelvis or pelvis and acetabulum: a double-blind, randomized, placebo-controlled trial † †This article is accompanied by the Editorial. ‡ ‡Declaration of interest. R. M. Grounds has worked in the past as a consultant for Novo Nordisk and has lectured at symposiums organized by Novo Nordisk. Novo Nordisk has given an unrestricted educational grant to St George’s Hospital Special Trustee’s. The trial was funded by Novo Nordisk, UK

Autor: Jonathan Ball, J. W. Redman, RM Grounds, G. Maloney, R Raobaikady

Publikováno v: British Journal of Anaesthesia. 94:586-591

Background Activated recombinant coagulation factor VII (rFVIIa) effectively prevents and controls bleeding in patients with coagulopathy. Data show that rFVIIa may reduce blood loss and eliminate the need for transfusion in patients with normal haem

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::163281f6e3e1d747906975997eb9c265
https://doi.org/10.1093/bja/aei102

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A prospective study into the use of NT-proBNP measurements in critically ill patients

Autor: F Boa, Andrew Rhodes, S Barnes, E. D. Bennett, RM Grounds, P. Collinson, R Tilley

Publikováno v: Clinical Intensive Care. 15:31-36

Objective: B-type natriuretic peptide (BNP) has been shown to be a sensitive marker of cardiac dysfunction and to increase in patients with septic shock. This study seeks to confirm these findings in a mixed group of critically ill patients.Design an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::45d14673f5fe0b45f6291da60dbd2b3a
https://doi.org/10.3109/09563070410001703923

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Calibration of three capnographs for use with helium and oxygen gas mixtures*

Autor: J. A. S. Ball, RM Grounds

Publikováno v: Anaesthesia. 58:156-160

Capnography is considered essential in the management of mechanically-ventilated patients. Helium, as an adjunct to mechanical ventilation, is the subject of renewed interest and used increasingly. However, helium affects the performance of infrared

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7dfb20f8877197a4bb87455cccdd07ca
https://doi.org/10.1046/j.1365-2044.2003.02963.x

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A phase II study to evaluate the efficacy of dexmedetomidine for sedation in the medical intensive care unit

Autor: R.M. Venn, RM Grounds, P. J. Newman

Publikováno v: Intensive Care Medicine. 29:201-207

Objective. To evaluate dexmedetomidine for sedation of patients in the medical ICU. Design and setting. Prospective observational study in an intensive care unit of a university hospital. Patients. Twelve ventilated patients with median APACHE II sco

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f04d75bb45c6fdcd9b2565e5ee458727
https://doi.org/10.1007/s00134-002-1579-9

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Improving post-operative morbidity and mortality

Autor: Andrews Rhodes, RM Grounds, Rebecca Cusack, J Ball

Publikováno v: Intensivmedizin und Notfallmedizin. 39:571-577

In certain groups of patients the risk of peri-operative death can be as high as 35% with up to 80% these deaths occurring in patients who develop post-operative multiple organ dysfunction syndrome (MODS). Patients at increased risk of death are easi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1c43f9301c591bce243550b6183802fa
https://doi.org/10.1007/s00390-002-0336-1

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The strong ion gap does not have prognostic value in critically ill patients in a mixed medical/surgical adult ICU

Autor: B Jordan, Andrew Rhodes, P Lochhead, Jonathan Ball, RM Grounds, Rebecca Cusack, E. D. Bennett, S Perry

Publikováno v: Intensive Care Medicine. 28:864-869

To examine whether the strong ion gap (SIG) or standard base excess corrected for abnormalities of serum chloride and albumin (BE(UA)) can predict outcome and to compare the prognostic abilities of these variables with standard base excess (SBE), ani

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2841bdf52238c9774f6447f6f5fd3a42
https://doi.org/10.1007/s00134-002-1318-2

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Comparison between dexmedetomidine and propofol for sedation in the intensive care unit: patient and clinician perceptions †

Autor: RM Grounds, R.M. Venn

Publikováno v: British Journal of Anaesthesia. 87:684-690

The alpha2 agonist dexmedetomidine is a new sedative and analgesic agent which is licensed in the USA for post-operative intensive care sedation. We compared dexmedetomidine with propofol in patients requiring sedation in intensive care. Twenty adult

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::158c5ca0b7003d6d4455a687de9f073c
https://doi.org/10.1093/bja/87.5.684

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A complicated case of myocardial rupture

Autor: S Brecker, RM Grounds, M Saha

Publikováno v: Clinical Intensive Care. 12:141-145

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f64c8f5370b34bb8adf83c42d81e1e08
https://doi.org/10.3109/tcic.12.3.141.145

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A review of the use of helium in the treatment of acute respiratory failure

Autor: J Ball, RM Grounds, Andrews Rhodes

Publikováno v: Clinical Intensive Care. 12:105-113

Helium was first isolated from the mineral cleavite in 1895. Its use, in place of nitrogen, as the carrier gas for oxygen was first described in the mid 1930s. It was recommended as an adjunct to the treatment of respiratory failure, in particular, f

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b059622224a6380b8e5f1d268cad6525
https://doi.org/10.3109/tcic.12.3.105.113

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