Prognostic importance of mutations in the ras proto-oncogenes in de novo acute myeloid leukemia

Autor: A Neubauer, RK Dodge, SL George, FR Davey, RT Silver, CA Schiffer, RJ Mayer, ED Ball, D Wurster-Hill, CD Bloomfield

Publikováno v: Blood. 83(6)

Mutations of the N- and K-ras genes are the most frequent genetic aberrations in acute myeloid leukemia (AML) and their detection in preleukemic conditions such as the myelodysplastic syndrome (MDS) suggests a role in the earliest phases of leukemoge

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c4d6bc634d9f0d5f182c8c43bc51483
https://pubmed.ncbi.nlm.nih.gov/8123851

Nonrandom abnormalities of chromosome 9p in childhood acute lymphoblastic leukemia: association with high-risk clinical features

Autor: SB Murphy, SC Raimondi, GK Rivera, M Crone, RK Dodge, FG Behm, CH Pui, DL Williams

Publikováno v: Blood. 74(1)

To assess the frequency and significance of nonrandom abnormalities of chromosome 9p in childhood acute lymphoblastic leukemia (ALL), we analyzed our experience with 398 consecutive cases with completely banded karyotypes. Forty cases (10%) with abno

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06d04d1d5829df26a35de4c81d062263
https://pubmed.ncbi.nlm.nih.gov/2752120

Prognostic importance of structural chromosomal abnormalities in children with hyperdiploid (greater than 50 chromosomes) acute lymphoblastic leukemia

Autor: CH Pui, SC Raimondi, RK Dodge, GK Rivera, LA Fuchs, M Abromowitch, AT Look, WL Furman, WM Crist, DL Williams

Publikováno v: Blood. 73(7)

Approximately one fourth of children with newly diagnosed acute lymphoblastic leukemia (ALL) have hyperdiploid (greater than 50 chromosomes) blasts and a relatively favorable prognosis. Nonetheless, a substantial proportion of these patients fail the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28b3acdf003f06e38d2a4c8620206359
https://pubmed.ncbi.nlm.nih.gov/2713510

Sequential multiagent chemotherapy is not superior to high-dose cytarabine alone as postremission intensification therapy for acute myeloid leukemia in adults under 60 years of age: Cancer and Leukemia Group B Study 9222.

Autor: Moore JO; University of Chicago, MC-2115, 5841 S Maryland Ave, Chicago, IL 60637, USA., George SL, Dodge RK, Amrein PC, Powell BL, Kolitz JE, Baer MR, Davey FR, Bloomfield CD, Larson RA, Schiffer CA

Publikováno v: Blood [Blood] 2005 May 01; Vol. 105 (9), pp. 3420-7. Date of Electronic Publication: 2004 Nov 30.

Differences in prognostic factors and outcomes in African Americans and whites with acute myeloid leukemia.

Autor: Sekeres MA; Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Department of Hematology and Medical Oncology, The Cleveland Clinic Foundation, Desk R35, 9500 Euclid Ave, Cleveland, OH 44195, USA. sekerem@ccf.org, Peterson B, Dodge RK, Mayer RJ, Moore JO, Lee EJ, Kolitz J, Baer MR, Schiffer CA, Carroll AJ, Vardiman JW, Davey FR, Bloomfield CD, Larson RA, Stone RM

Publikováno v: Blood [Blood] 2004 Jun 01; Vol. 103 (11), pp. 4036-42. Date of Electronic Publication: 2004 Feb 19.