Zobrazeno 1 - 10
of 2 458
pro vyhledávání: '"RIPK1"'
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-14 (2024)
Abstract Background Gasdermin D (GSDMD) mediated pyroptosis plays a significant role in the pathophysiology of myocardial ischemia/reperfusion (I/R) injury. However, the precise mechanisms regulating pyroptosis remain unclear. In the study, we aimed
Externí odkaz:
https://doaj.org/article/eb4c0f7c7629491c8ed000db7ef3a490
Autor:
Qichao Gong, Tahir Ali, Yue Hu, Ruyan Gao, Shengnan Mou, Yanhua Luo, Canyu Yang, Axiang Li, Tao Li, Liang Liang Hao, Liufang He, Xiaoming Yu, Shupeng Li
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-17 (2024)
Abstract Background Depression is often linked to inflammation in the brain. Researchers have been exploring ways to reduce this inflammation to improve depression symptoms. One potential target is a protein called RIPK1, which is known to contribute
Externí odkaz:
https://doaj.org/article/05d6e7b5926b4d0aa5771b8c232f6a3f
Autor:
Xianya Cao, Junlan Tan, Runxiu Zheng, Feiying Wang, Lingling Zhou, Jian Yi, Rong Yuan, Qin Dai, Lan Song, Aiguo Dai
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-23 (2024)
Abstract Respiratory diseases are a growing concern in public health because of their potential to endanger the global community. Cell death contributes critically to the pathophysiology of respiratory diseases. Recent evidence indicates that necropt
Externí odkaz:
https://doaj.org/article/d333c47f4bab4e69a72ade8720521950
Publikováno v:
Cell Regeneration, Vol 13, Iss 1, Pp 1-15 (2024)
Abstract Intestinal epithelial cells (IECs) are pivotal for maintaining intestinal homeostasis through self-renewal, proliferation, differentiation, and regulated cell death. While apoptosis and necroptosis are recognized as distinct pathways, their
Externí odkaz:
https://doaj.org/article/e63cbb41294e4a50bfd44d742a16ece9
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-19 (2024)
Abstract Many DNA viruses develop various strategies to inhibit cell death to facilitate their replication. However, whether influenza A virus (IAV), a fast-replicating RNA virus, attenuates cell death remains unknown. Here, we report that IAV infect
Externí odkaz:
https://doaj.org/article/2ab463230aee4676807d10cad6331be4
Publikováno v:
Shanghai Jiaotong Daxue xuebao. Yixue ban, Vol 44, Iss 6, Pp 788-794 (2024)
Receptor-interacting protein kinase 1 (RIPK1) is a multi-domain serine/threonine protein kinase that causes downstream signal transduction and biological effects by phosphorylating specific proteins. In recent years, with the in-depth study of RIPK1,
Externí odkaz:
https://doaj.org/article/faf8e0e8eefc4d98ac3efeafe0afc881
Publikováno v:
Biology Direct, Vol 19, Iss 1, Pp 1-17 (2024)
Abstract Background There is growing evidence indicating that deubiquitinating enzymes may contribute to tumor progression and can serve as promising therapeutic targets. Methods The overexpression of deubiquitinase OTUD6B in lung adenocarcinoma (LUA
Externí odkaz:
https://doaj.org/article/47f6750ee0324ada80b0f18e8659c34b
Autor:
Limeng Wang, Zehua Shao, Ning Wang, Wenna Liu, Lina Zhang, Yanliang Wang, Jing Tan, Xiaojing Jiao, Lu Liu, Lei Yan, Song Chen, Huixia Cao, Fengmin Shao
Publikováno v:
Ecotoxicology and Environmental Safety, Vol 284, Iss , Pp 116944- (2024)
Aristolochic acid (AA) exposure is a severe public health concern worldwide. AAs damage the kidney with an inevitable acute phase that is similar to acute kidney injury (AKI). Gasdermin E (GSDME) is abundant in the kidney; thus; it-mediated pyroptosi
Externí odkaz:
https://doaj.org/article/a774fa99b9894252afe05eeb9383c897
Autor:
Önay Veli, Öykü Kaya, Ana Beatriz Varanda, Ximena Hildebrandt, Peng Xiao, Yann Estornes, Matea Poggenberg, Yuan Wang, Manolis Pasparakis, Mathieu J.M. Bertrand, Henning Walczak, Alessandro Annibaldi, Alessandra K. Cardozo, Nieves Peltzer
Publikováno v:
Molecular Metabolism, Vol 87, Iss , Pp 101988- (2024)
Objective: Receptor-interacting protein kinase 1 (RIPK1) orchestrates the decision between cell survival and cell death in response to tumor necrosis factor (TNF) and other cytokines. Whereas the scaffolding function of RIPK1 is crucial to prevent TN
Externí odkaz:
https://doaj.org/article/cbfaa1b06b424a17bd878d06feedd620
Autor:
Ratnakar R. Bynigeri, R. K. Subbarao Malireddi, Raghvendra Mall, Jon P. Connelly, Shondra M. Pruett-Miller, Thirumala-Devi Kanneganti
Publikováno v:
BMC Biology, Vol 22, Iss 1, Pp 1-11 (2024)
Abstract Background The innate immune system serves as the first line of host defense. Transforming growth factor-β–activated kinase 1 (TAK1) is a key regulator of innate immunity, cell survival, and cellular homeostasis. Because of its importance
Externí odkaz:
https://doaj.org/article/6c8aa98cb49f4dbe90bd184bed5e3736