Zobrazeno 1 - 6
of 6
pro vyhledávání: '"RIP, Rat insulin promoter"'
Autor:
Nada Mohamed, Ting Zhang, Justin Molitoris, Krishna Prasadan, Mohamed Saleh, Yan Wang, Anuradha Sehrawat, Ranjeet Kalsi, Madison Thomas, George K. Gittes
Publikováno v:
The Journal of Biological Chemistry
Understanding signaling pathways that regulate pancreatic β-cell function to produce, store, and release insulin, as well as pathways that control β-cell proliferation, is vital to find new treatments for diabetes mellitus. Transforming growth fact
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9bf2363f38cde8af23f109fca39a28ff
https://pubmed.ncbi.nlm.nih.gov/34582892
https://pubmed.ncbi.nlm.nih.gov/34582892
Autor:
Kyle S. McCommis, Jerry R. Colca, Dakota R. Kamm, Laura N. Healy, Martin C. Sharpe, Kelly D. Pyles
Publikováno v:
The Journal of Biological Chemistry
Insulin sensitizers and incretin mimetics are antidiabetic agents with vastly different mechanisms of action. Thiazolidinedione (TZD) insulin sensitizers are associated with weight gain, whereas glucagon-like peptide-1 receptor agonists can induce we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be842022a0f9bc0e85ea8d47048c5426
https://pubmed.ncbi.nlm.nih.gov/34022222
https://pubmed.ncbi.nlm.nih.gov/34022222
Publikováno v:
Molecular Metabolism
Molecular Metabolism, Vol 11, Iss, Pp 212-217 (2018)
Molecular Metabolism, Vol 11, Iss, Pp 212-217 (2018)
Objective Both Type I and Type II diabetes mellitus result from insufficient functional β-cell mass. Efforts to increase β-cell proliferation as a means to restore β-cell mass have been met with limited success. Suppression of Tumorigenicity 5 (ST
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6cb32edef3707abead555b72e794c88
http://europepmc.org/articles/PMC6001393
http://europepmc.org/articles/PMC6001393
Autor:
Per Olof Berggren, Shao-Nian Yang
Publikováno v:
Pharmacology & Therapeutics
Diabetes develops due to deficient functional β cell mass, insulin resistance, or both. Yet, various challenges in understanding the mechanisms underlying diabetes development in vivo remain to be overcome owing to the lack of appropriate intravital
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6fa0cc54977ee585479065e69678f400
https://pubmed.ncbi.nlm.nih.gov/30677477
https://pubmed.ncbi.nlm.nih.gov/30677477
Publikováno v:
Current Opinion in Immunology
The breaking of tolerance or unresponsiveness to self-antigens, involving the activation of autoreactive lymphocytes, is a critical event leading to autoimmune diseases. The precise mechanisms by which this can occur are mostly unknown. Viruses have
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db8592fdc5456a7ca32319ef6df8336a
http://europepmc.org/articles/PMC7134972
http://europepmc.org/articles/PMC7134972
Autor:
Shamsi F; a Max-Planck Institute for Biophysical Chemistry ; Department of Molecular Cell Biology ; RG Molecular Cell Differentiation ; Goettingen , Germany., Parlato R, Collombat P, Mansouri A
Publikováno v:
Cell cycle (Georgetown, Tex.) [Cell Cycle] 2014; Vol. 13 (24), pp. 3948-57.