Zobrazeno 1 - 10
of 3 673
pro vyhledávání: '"RIMAS"'
Autor:
Víctor A. Arrieta, Andrew Gould, Kwang-Soo Kim, Karl J. Habashy, Crismita Dmello, Gustavo I. Vázquez-Cervantes, Irina Palacín-Aliana, Graysen McManus, Christina Amidei, Cristal Gomez, Silpol Dhiantravan, Li Chen, Daniel Y. Zhang, Ruth Saganty, Meghan E. Cholak, Surya Pandey, Matthew McCord, Kathleen McCortney, Brandyn Castro, Rachel Ward, Miguel Muzzio, Guillaume Bouchoux, Carole Desseaux, Michael Canney, Alexandre Carpentier, Bin Zhang, Jason M. Miska, Maciej S. Lesniak, Craig M. Horbinski, Rimas V. Lukas, Roger Stupp, Catalina Lee-Chang, Adam M. Sonabend
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract Given the marginal penetration of most drugs across the blood-brain barrier, the efficacy of various agents remains limited for glioblastoma (GBM). Here we employ low-intensity pulsed ultrasound (LIPU) and intravenously administered microbub
Externí odkaz:
https://doaj.org/article/79679c002d644430b29884550815aa26
Autor:
Priya Kumthekar, Madison Lyleroehr, Leilani Lacson, Rimas V. Lukas, Karan Dixit, Roger Stupp, Timothy Kruser, Jeff Raizer, Alexander Hou, Sean Sachdev, Margaret Schwartz, Jessica Bajas PA, Ray Lezon, Karyn Schmidt, Christina Amidei, Karen Kaiser
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-11 (2024)
Abstract Background Tumor Treating Fields (TTFields) Therapy is an FDA-approved therapy in the first line and recurrent setting for glioblastoma. Despite Phase 3 evidence showing improved survival with TTFields, it is not uniformly utilized. We aimed
Externí odkaz:
https://doaj.org/article/d7895edb0e734564b205c572113db00c
Autor:
Erik E. Rabin, Jonathan Huang, Miri Kim, Andreas Mozny, Kristen L. Lauing, Manon Penco-Campillo, Lijie Zhai, Prashant Bommi, Xinlei Mi, Erica A. Power, Vikram C. Prabhu, Douglas E. Anderson, Kevin P. Barton, Theresa L. Walunas, Gary E. Schiltz, Christina Amidei, Pilar Sanchez-Gomez, Jigisha P. Thakkar, Rimas V. Lukas, Derek A. Wainwright
Publikováno v:
Brain, Behavior, & Immunity - Health, Vol 38, Iss , Pp 100753- (2024)
Background: Increased age is a strong and unfavorable prognostic factor for patients with glioblastoma (GBM). However, the relationships between stratified patient age, comorbidities, and medications have yet to be explored in GBM patient survival an
Externí odkaz:
https://doaj.org/article/841cdbd3c0e44477be3cf471311e57cb
Publikováno v:
Heliyon, Vol 10, Iss 11, Pp e31410- (2024)
A scrutiny analysis of the COVID-19 data is required to get insights into effective strategies for pandemic control. However, there is a gap between official data and methods used to assess the effectiveness of the potential measures, which was partl
Externí odkaz:
https://doaj.org/article/d19d4a0b800e482bbd87ac378c33f655
Autor:
Matthew McCord, Pouya Jamshidi, Vineeth Thirunavu, Lucas Santana-Santos, Erica Vormittag-Nocito, David Dittman, Stephanie Parker, Joseph Baczkowski, Lawrence Jennings, Jordain Walshon, Kathleen McCortney, Kristyn Galbraith, Hui Zhang, Rimas V. Lukas, Roger Stupp, Karan Dixit, Priya Kumthekar, Amy B. Heimberger, Matija Snuderl, Craig Horbinski
Publikováno v:
Acta Neuropathologica Communications, Vol 11, Iss 1, Pp 1-15 (2023)
Abstract MGMT promoter methylation testing is required for prognosis and predicting temozolomide response in gliomas. Accurate results depend on sufficient tumor cellularity, but histologic estimates of cellularity are subjective. We sought to determ
Externí odkaz:
https://doaj.org/article/c76fde180aa142ce9de66226ad2f660b
Autor:
Ruochen Du, Shashwat Tripathi, Hinda Najem, Daniel J. Brat, Rimas V. Lukas, Peng Zhang, Amy B. Heimberger
Publikováno v:
Cells, Vol 13, Iss 10, p 823 (2024)
Macrophages and microglia are professional phagocytes that sense and migrate toward “eat-me” signals. The role of phagocytic cells is to maintain homeostasis by engulfing senescent or apoptotic cells, debris, and abnormally aggregated macromolecu
Externí odkaz:
https://doaj.org/article/6bc6d5a7ca8d412085c42601a729f555
Autor:
Yang Liu, Rimas J Orentas, Ying Xiong, Zhongyu Zhu, Yanping Xie, Matthew Addington-Hall, Beatrix Ferencz, Tony Luo, Maggie Yates, Oxana Slessareva, Ibeawuchi Oparaocha, Boro Dropulić
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/2fa66efa34a54a469cddd61d64514e43
Autor:
Rimas Norvaiša
Publikováno v:
Lietuvos Matematikos Rinkinys, Vol 64, Iss B (2023)
The article discusses the problems of definitions of concepts of school mathematics in textbooks. Excerpts from textbooks show how interpretations of a fraction having no necessary properties of a mathematical definition have changed over the decades
Externí odkaz:
https://doaj.org/article/90595025b30b4b0093303559589be75b
Autor:
Ugne Kuliesiute, Rimas Prokopovicius, Ugne Kisieliute, Kajus Merkevicius, Gediminas Luksys, Saulius Rocka, Urte Neniskyte
Publikováno v:
IBRO Neuroscience Reports, Vol 15, Iss , Pp S111- (2023)
Externí odkaz:
https://doaj.org/article/16d82a9200d8421594b81263001e41d2
Autor:
Scott A Wu, Dan Tong Jia, Margaret Schwartz, Mary Mulcahy, Kuanghua Guo, Matthew C Tate, Sean Sachdev, Nicolas Kostelecky, David J Escobar, Daniel J Brat, Amy B Heimberger, Rimas V Lukas
Publikováno v:
CNS Oncology, Vol 12, Iss 3 (2023)
Materials & methods: We recently reported the largest trial of breast cancer patients with HER2 positive leptomeningeal metastases (LM) treated with trastuzumab. An additional treatment indication was explored as part of a single institution retrospe
Externí odkaz:
https://doaj.org/article/71908c412a07460c9e77e4e1c8dc9f98