The impact of methodology on the reproducibility and rigor of DNA methylation data

Autor: Detlev Boison, Susan A. Masino, Farah D. Lubin, Kai Guo, Theresa Lusardi, Richard Sanchez, David N. Ruskin, Joyce Ohm, Jonathan D. Geiger, Junguk Hur

Publikováno v: Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)

Abstract Epigenetic modifications are crucial for normal development and implicated in disease pathogenesis. While epigenetics continues to be a burgeoning research area in neuroscience, unaddressed issues related to data reproducibility across labor

Externí odkaz: https://doaj.org/article/07e8511c0c8240bcb8721f26619b6d55

Analysis of alpha modes in multigroup diffusion

Autor: Richard Sanchez, Daniele Tomatis, Igor Zmijarevic, Han Gyu Joo

Publikováno v: Nuclear Engineering and Technology, Vol 49, Iss 6, Pp 1259-1268 (2017)

The alpha eigenvalue problem in multigroup neutron diffusion is studied with particular attention to the theoretical analysis of the model. Contrary to previous literature results, the existence of eigenvalue and eigenflux clustering is investigated

Externí odkaz: https://doaj.org/article/88f8eca8d7814135afb0328ef707e63f

On SP theory

Autor: Richard Sanchez

Publikováno v: Annals of Nuclear Energy. 129:331-349

We have generalized Pomraning’s variational derivation of the Simplified PN (SPN) method and apply it to the first-order transport equation with anisotropic scattering and sources without restriction on the parity of N. The result is a new system o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::15542f6df1da8e8ca5309d7b5faece96
https://doi.org/10.1016/j.anucene.2019.01.044

A MOC-based neutron kinetics model for noise analysis

Autor: A. Gammicchia, Sandra Dulla, Simone Santandrea, Z. Stankovski, P. Mosca, Richard Sanchez, Igor Zmijarevic

Publikováno v: Annals of Nuclear Energy
Annals of Nuclear Energy, Elsevier Masson, 2020, 137, pp.107070-. ⟨10.1016/j.anucene.2019.107070⟩
Annals of Nuclear Energy, 2020, 137, pp.107070-. ⟨10.1016/j.anucene.2019.107070⟩

A 2-D noise model is implemented in the deterministic reactor code APOLLO3® to simulate a periodic oscillation of a structural component. The Two/Three Dimensional Transport (TDT) solver, using the Method of Characteristics, is adopted for the calcu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f2766411898a3a661ef1c27a2dad149
https://hal.archives-ouvertes.fr/hal-03488749

A reduced-basis element method for pin-by-pin reactor core calculations in diffusion andSP3approximations

Autor: Alexey Cherezov, Han Gyu Joo, Richard Sanchez

Publikováno v: Annals of Nuclear Energy. 116:195-209

The reduced order model (ROM) methods allow to significantly improve the computation time and memory usage. Therefore these methods are very useful for real-time or many-query reactor core simulation analysis. The ROM approach is based on the proper

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4b66111e74fcf916b3aafb7d502cd030
https://doi.org/10.1016/j.anucene.2018.02.013