Zobrazeno 1 - 10
of 807
pro vyhledávání: '"RICHARD J. ROMAN"'
Autor:
Yang Ou, Brad A Clifton, Jinghui Li, David Sandlin, Na Li, Li Wu, Chunming Zhang, Tianwen Chen, Jun Huang, Yue Yu, Jerome Allison, Fan Fan, Richard J Roman, James Shaffery, Wu Zhou, Yi Pang, Hong Zhu
Publikováno v:
Neural Regeneration Research, Vol 17, Iss 1, Pp 115-121 (2022)
Exposure to explosive shockwave often leads to blast-induced traumatic brain injury in military and civilian populations. Unprotected ears are most often damaged following exposure to blasts. Although there is an association between tympanic membrane
Externí odkaz:
https://doaj.org/article/05be1555da474807b4d407d95446238d
Publikováno v:
Frontiers in Aging, Vol 3 (2022)
Although the causes of cognitive impairment are multifactorial, emerging evidence indicates that cerebrovascular dysfunction plays an essential role in dementia. One of the most critical aspects of cerebrovascular dysfunction is autoregulation of cer
Externí odkaz:
https://doaj.org/article/bef8919a9b214ddbbdc65b9a4ecda7a2
Autor:
Junie P. Warrington, Fan Fan, Jeremy Duncan, Mark W. Cunningham, Babette B. LaMarca, Ralf Dechend, Gerd Wallukat, Richard J. Roman, Heather A. Drummond, Joey P. Granger, Michael J. Ryan
Publikováno v:
Biology of Sex Differences, Vol 10, Iss 1, Pp 1-8 (2019)
Abstract Background Placental ischemia and hypertension, characteristic features of preeclampsia, are associated with impaired cerebral blood flow (CBF) autoregulation and cerebral edema. However, the factors that contribute to these cerebral abnorma
Externí odkaz:
https://doaj.org/article/3faa9b7e7c044e9e8fbb15617256efe5
Autor:
Ezekiel Gonzalez-Fernandez, Daniel Staursky, Kathryn Lucas, Bond V. Nguyen, Man Li, Yedan Liu, Chad Washington, Lique M. Coolen, Fan Fan, Richard J. Roman
Publikováno v:
Frontiers in Neurology, Vol 11 (2020)
20-HETE is a potent vasoconstrictor that is implicated in the regulation of blood pressure, cerebral blood flow and neuronal death following ischemia. Numerous human genetic studies have shown that inactivating variants in the cytochrome P450 enzymes
Externí odkaz:
https://doaj.org/article/1ef8b5704a394a9c9240143c37a0137d
Autor:
Huawei Zhang, Chao Zhang, Yedan Liu, Wenjun Gao, Shaoxun Wang, Xing Fang, Ya Guo, Man Li, Ruen Liu, Richard J. Roman, Peng Sun, Fan Fan
Publikováno v:
Physiological Reports, Vol 8, Iss 2, Pp n/a-n/a (2020)
Abstract We recently reported that KO of Dual‐specificity protein phosphatase 5 (Dusp5) enhances myogenic reactivity and blood flow autoregulation in the cerebral and renal circulations in association with increased levels of pPKC and pERK1/2 in th
Externí odkaz:
https://doaj.org/article/9f34c41df2414f319e7936b45ad178f9
Publikováno v:
Chinese Medical Journal, Vol 131, Iss 1, Pp 63-68 (2018)
Background: Intervertebral disc degeneration (IDD) is a major cause of disc protrusion, likely to be associated with decrease of water content. This research aimed to evaluate IDD by diffusion-weighted imaging (DWI) with a 7.0 Tesla (T) magnetic reso
Externí odkaz:
https://doaj.org/article/0e439de0e8c5408390bc19a2af11bd82
Publikováno v:
Journal of Cardiovascular Pharmacology. 80:206-209
Septic shock is life-threatening organ dysfunction due to a dysregulated response to infection. It is a leading cause of death caused by the excessive release of cytokines and inflammatory mediators in response to bacterial endotoxins. It produces hy
Autor:
Letao Fan, Shaoxun Wang, Xiaochen He, Ezekiel Gonzalez‐Fernandez, Claude Lechene, Fan Fan, Richard J. Roman
Publikováno v:
Physiological Reports, Vol 7, Iss 8, Pp n/a-n/a (2019)
Abstract This study describes a modified technique to fill the renal vasculature with a silicon rubber (Microfil) compound and obtain morphologic information about the intrarenal distribution of capillary blood flow under a variety of conditions. Kid
Externí odkaz:
https://doaj.org/article/2f21f99aa78246ff8039ae69afcdac78
Akademický článek
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Publikováno v:
ASPET 2023 Annual Meeting Abstract - Drug Discovery and Development.