Zobrazeno 1 - 10
of 408
pro vyhledávání: '"RICHARD J. BAROHN"'
Autor:
Omar Jawdat, Jason Rucker, Tomoki Nakano, Kotaro Takeno, Jeffery Statland, Mamatha Pasnoor, Mazen M. Dimachkie, Carla Sabus, Yomna Badawi, Suzanne L. Hunt, Naoko H. Tomioka, Sumedha Gunewardena, Clark Bloomer, Heather M. Wilkins, Laura Herbelin, Richard J. Barohn, Hiroshi Nishimune
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract Amyotrophic lateral sclerosis (ALS) patients lack effective treatments to maintain motor and neuromuscular function. This study aimed to evaluate the effect of a home-based exercise program on muscle strength, ALS scores, and transcriptome i
Externí odkaz:
https://doaj.org/article/e3237184e1bb4c6f98062c0787594ebf
Autor:
Alexandra R. Brown, Byron J. Gajewski, Dinesh Pal Mudaranthakam, Mamatha Pasnoor, Mazen M. Dimachkie, Omar Jawdat, Laura Herbelin, Matthew S. Mayo, Richard J. Barohn
Publikováno v:
Contemporary Clinical Trials Communications, Vol 36, Iss , Pp 101220- (2023)
Background: Response adaptive randomization is popular in adaptive trial designs, but the literature detailing its execution is lacking. These designs are desirable for patients/stakeholders, particularly in comparative effectiveness research, due to
Externí odkaz:
https://doaj.org/article/b52e6d82e8a64ea2a96d8818dd50de39
Autor:
Alexander A. Brown, Bradley J. Ferguson, Vovanti Jones, Bruce E. Green, Justin D. Pearre, Ifeoma A. Anunoby, David Q. Beversdorf, Richard J. Barohn, Carmen M. Cirstea
Publikováno v:
Frontiers in Artificial Intelligence, Vol 5 (2022)
AimsCardiovascular dysautonomia may impact the quality of life and survival in amyotrophic lateral sclerosis (ALS). Such dysfunction is not systematically assessed in these patients. Wearable devices could help. The feasibility of a wearable biosenso
Externí odkaz:
https://doaj.org/article/fa24ce23e85b494399f41c001e1cdbe2
Autor:
Sudheer K. Tungtur, Heather M. Wilkins, Robert S. Rogers, Yomna Badawi, Jessica M. Sage, Abdulbaki Agbas, Omar Jawdat, Richard J. Barohn, Russell H. Swerdlow, Hiroshi Nishimune
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract Amyotrophic lateral sclerosis (ALS) remains a devastating motor neuron disease with limited treatment options. Oxaloacetate treatment has a neuroprotective effect in rodent models of seizure and neurodegeneration. Therefore, we treated the A
Externí odkaz:
https://doaj.org/article/38dec4f7c64841b98b4be34960b67c6f
Autor:
Alex G. Karanevich, Luke J. Weisbrod, Omar Jawdat, Richard J. Barohn, Byron J. Gajewski, Jianghua He, Jeffrey M. Statland
Publikováno v:
BMC Neurology, Vol 18, Iss 1, Pp 1-7 (2018)
Abstract Background To assess the feasibility of using automated capture of Electronic Medical Record (EMR) data to build predictive models for amyotrophic lateral sclerosis (ALS) outcomes. Methods We used an Informatics for Integrating Biology and t
Externí odkaz:
https://doaj.org/article/4e6a36e0d80343fca800074767fe6433
Autor:
Rebecca A. Crow, Kimberly A. Hart, Michael P. McDermott, Rabi Tawil, William B. Martens, Barbara E. Herr, Elaine McColl, Jennifer Wilkinson, Janbernd Kirschner, Wendy M. King, Michele Eagle, Mary W. Brown, Deborah Hirtz, Hanns Lochmuller, Volker Straub, Emma Ciafaloni, Perry B. Shieh, Stefan Spinty, Anne-Marie Childs, Adnan Y. Manzur, Lucia Morandi, Russell J. Butterfield, Iain Horrocks, Helen Roper, Kevin M. Flanigan, Nancy L. Kuntz, Jean K. Mah, Leslie Morrison, Basil T. Darras, Maja von der Hagen, Ulrike Schara, Ekkehard Wilichowski, Tiziana Mongini, Craig M. McDonald, Giuseppe Vita, Richard J. Barohn, Richard S. Finkel, Matthew Wicklund, Hugh J. McMillan, Imelda Hughes, Elena Pegoraro, W. Bryan Burnette, James F. Howard, Mathula Thangarajh, Craig Campbell, Robert C. Griggs, Kate Bushby, Michela Guglieri
Publikováno v:
Trials, Vol 19, Iss 1, Pp 1-9 (2018)
Abstract Background Trials in rare diseases have many challenges, among which are the need to set up multiple sites in different countries to achieve recruitment targets and the divergent landscape of clinical trial regulations in those countries. Ov
Externí odkaz:
https://doaj.org/article/59fc2ba5f36543fab1efe37a189c7b3f
Publikováno v:
Communications in Statistics: Case Studies, Data Analysis and Applications. :1-18
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::343f1b948ec39ddc26704cfb32443370
https://doi.org/10.1080/23737484.2023.2212262
https://doi.org/10.1080/23737484.2023.2212262
Autor:
Mamatha Pasnoor, Vera Bril, Todd Levine, Jaya Trivedi, Nicholas J. Silvestri, Milind Phadnis, Hans D. Katzberg, David S. Saperstein, Gil I. Wolfe, Laura Herbelin, Kiley Higgs, Andrew J. Heim, Jeffrey M. Statland, Richard J. Barohn, Mazen M. Dimachkie
Publikováno v:
European Journal of Neurology. 30:1417-1424
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2b29a0e14f4f20d67e833fa00ad403e4
https://doi.org/10.1111/ene.15745
https://doi.org/10.1111/ene.15745
Autor:
Andrew L Mammen, Anthony A Amato, Mazen M Dimachkie, Hector Chinoy, Yessar Hussain, James B Lilleker, Iago Pinal-Fernandez, Yves Allenbach, Babak Boroojerdi, Mark Vanderkelen, Eumorphia Maria Delicha, Harold Koendgen, Ramin Farzaneh-Far, Petra W Duda, Camil Sayegh, Olivier Benveniste, Anthony A. Amato, Suur Biliciler, Mazen M. Dimachkie, Christyn Edmundson, Miriam Freimer, Anthony Geraci, Pedro Machado, Andrew L. Mammen, Tahseen Mozaffar, Payam Soltanzadeh, Niraja Suresh, Anneke van der Kooi, Matthew Appleby, Richard J Barohn, Nicolas Champtiaux, Christopher Doughty, Jerrica Farias, Constantine Farmakidis, Ali A. Habib, Chafic Karam, James Lilleker, Samantha Lorusso, Mamatha Pasnoor, Giorgia Querin, Joost Raaphorst, George Ransley, Sami Saba, Kazim Sheikh, Andrew Snedden, Jeffrey Statland, Tuan Vu
Publikováno v:
The Lancet Rheumatology, 5(2), e67-e76. Lancet Publishing Group
Background: Immune-mediated necrotising myopathy is an autoimmune myopathy characterised by proximal muscle weakness, high creatine kinase concentrations, and autoantibodies recognising 3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMGCR) or the s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::226dfb286f8e7e3dd1c850014b828f66
https://doi.org/10.1016/s2665-9913(23)00003-6
https://doi.org/10.1016/s2665-9913(23)00003-6
Autor:
Salman F, Bhai, Alexandra, Brown, Byron, Gajewski, Kim S, Kimminau, Lemuel R, Waitman, Mamatha, Pasnoor, Richard J, Barohn
Publikováno v:
Muscle & Nerve. 66:404-410
Peripheral neuropathies commonly affect quality of life of patients due to pain, sleep disturbances, and fatigue, although trials have not adequately explored these domains of care. The aim of this study was to assess the impact of nortriptyline, dul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1299d44f646330f452ae7ee497bcef39
https://doi.org/10.1002/mus.27637
https://doi.org/10.1002/mus.27637