Zobrazeno 1 - 10
of 477
pro vyhledávání: '"RICHARD E. PRATLEY"'
Autor:
Laura M. Jacobsen, Jennifer L. Sherr, Elizabeth Considine, Angela Chen, Sarah M. Peeling, Margo Hulsmans, Sara Charleer, Marzhan Urazbayeva, Mustafa Tosur, Selma Alamarie, Maria J. Redondo, Korey K. Hood, Peter A. Gottlieb, Pieter Gillard, Jessie J. Wong, Irl B. Hirsch, Richard E. Pratley, Lori M. Laffel, Chantal Mathieu, ADA/EASD PMDI
Publikováno v:
Communications Medicine, Vol 3, Iss 1, Pp 1-24 (2023)
Abstract Background The greatest change in the treatment of people living with type 1 diabetes in the last decade has been the explosion of technology assisting in all aspects of diabetes therapy, from glucose monitoring to insulin delivery and decis
Externí odkaz:
https://doaj.org/article/58b9c96d2c334d6da4dd72be5fec5eec
Autor:
Karen D. Corbin, Elvis A. Carnero, Blake Dirks, Daria Igudesman, Fanchao Yi, Andrew Marcus, Taylor L. Davis, Richard E. Pratley, Bruce E. Rittmann, Rosa Krajmalnik-Brown, Steven R. Smith
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Abstract The gut microbiome is emerging as a key modulator of human energy balance. Prior studies in humans lacked the environmental and dietary controls and precision required to quantitatively evaluate the contributions of the gut microbiome. Using
Externí odkaz:
https://doaj.org/article/8895c80e640d4708af1ef33f4c92caed
Autor:
Anna Casu, Yury O. Nunez Lopez, Gongxin Yu, Christopher Clifford, Anika Bilal, Alejandra M. Petrilli, Heather Cornnell, Elvis Alvarez Carnero, Ananya Bhatheja, Karen D. Corbin, Anton Iliuk, David M. Maahs, Richard E. Pratley
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2023)
IntroductionThere are no validated clinical or laboratory biomarkers to identify and differentiate endotypes of type 1 diabetes (T1D) or the risk of progression to chronic complications. Extracellular vesicles (EVs) have been studied as biomarkers in
Externí odkaz:
https://doaj.org/article/8c965ea96b4345fca91e6b64f3d26101
Autor:
Yury O. Nunez Lopez, Anna Casu, Zuzana Kovacova, Alejandra M. Petrilli, Olga Sideleva, William G. Tharp, Richard E. Pratley
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
Pioglitazone, a PPARγ agonist, is used to treat type 2 diabetes (T2D). PPARγ is highly expressed in adipose tissue (AT), however the effects of pioglitazone to improve insulin sensitivity are also evident in other tissues and PPARγ agonism has bee
Externí odkaz:
https://doaj.org/article/fdfc0e0b0b624c89a1fbb9eb2320c5cf
Autor:
Franziska K. Bishop, Ananta Addala, Karen D. Corbin, Franklin R. Muntis, Richard E. Pratley, Michael C. Riddell, Elizabeth J. Mayer-Davis, David M. Maahs, Dessi P. Zaharieva
Publikováno v:
Nutrients, Vol 15, Iss 11, p 2500 (2023)
The prevalence of overweight and obesity in young people with type 1 diabetes (T1D) now parallels that of the general population. Excess adiposity increases the risk of cardiovascular disease, which is already elevated up to 10-fold in T1D, underscor
Externí odkaz:
https://doaj.org/article/3037f688b29f4ce693a292b353b09e85
Publikováno v:
Frontiers in Nutrition, Vol 9 (2022)
The Ile191Val variant of the TAS1R2 gene of sweet taste receptors causes a partial loss-of-function and is associated with reduced glucose excursions in a healthy lean cohort. However, it is unclear whether this polymorphism contributes to the regula
Externí odkaz:
https://doaj.org/article/8c5042e5607e459bba5bf54cc98881ba
Autor:
Joan Serrano, Kathleen R. Smith, Audra L. Crouch, Vandana Sharma, Fanchao Yi, Veronika Vargova, Traci E. LaMoia, Lydia M. Dupont, Vanida Serna, Fenfen Tang, Laisa Gomes-Dias, Joshua J. Blakeslee, Emmanuel Hatzakis, Scott N. Peterson, Matthew Anderson, Richard E. Pratley, George A. Kyriazis
Publikováno v:
Microbiome, Vol 9, Iss 1, Pp 1-18 (2021)
Abstract Background Non-caloric artificial sweeteners (NCAS) are widely used as a substitute for dietary sugars to control body weight or glycemia. Paradoxically, some interventional studies in humans and rodents have shown unfavorable changes in glu
Externí odkaz:
https://doaj.org/article/fd0e743042a248bcaf59acc1822c7f2d
Autor:
Richard E. Pratley, Mansoor Husain, Ildiko Lingvay, Thomas R. Pieber, Thomas Mark, Hans A. Saevereid, Daniel Vega Møller, Bernard Zinman, the DEVOTE Study Group
Publikováno v:
Cardiovascular Diabetology, Vol 18, Iss 1, Pp 1-11 (2019)
Abstract Background Heart failure (HF) is a common cardiovascular complication of type 2 diabetes (T2D). This secondary analysis investigated baseline factors and treatment differences associated with risk of hospitalization for HF (hHF), and the pos
Externí odkaz:
https://doaj.org/article/a1749550eef4462cae1c6531320271cc
Autor:
Joan Serrano, Jaroslava Seflova, Jihye Park, Marsha Pribadi, Keisuke Sanematsu, Noriatsu Shigemura, Vanida Serna, Fanchao Yi, Andrea Mari, Erik Procko, Richard E. Pratley, Seth L. Robia, George A. Kyriazis
Publikováno v:
Molecular Metabolism, Vol 54, Iss , Pp 101339- (2021)
Objective: Sweet taste receptors (STR) are expressed in the gut and other extra-oral tissues, suggesting that STR-mediated nutrient sensing may contribute to human physiology beyond taste. A common variant (Ile191Val) in the TAS1R2 gene of STR is ass
Externí odkaz:
https://doaj.org/article/1acbd0e244fc4d53855f831ccf780d78
Publikováno v:
Molecular Metabolism, Vol 20, Iss , Pp 63-78 (2019)
Objective: Short-term intensive insulin therapy (IIT) early in the course of type 2 diabetes acutely improves beta-cell function with long-lasting effects on glycemic control. However, conventional measures cannot determine which patients are better
Externí odkaz:
https://doaj.org/article/a369a9cf9b9c4ee6abbe0ae2deb82333