Zobrazeno 1 - 10
of 67
pro vyhledávání: '"RICHARD E. MORRISSEY"'
Publikováno v:
Reproductive Toxicology. 17:691-697
Normal pre- and postnatal male reproductive development and function is dependent upon testicular androgen production and is sensitive to antiandrogenic perturbations. It was of interest to determine if the H(1) histamine antagonist loratadine had th
Autor:
James E. Patrick, Christopher Horvath, Richard E. Morrissey, Eileen A. Snyder, James S. MacDonald
Publikováno v:
Toxicological Sciences. 65:266-275
SCH 58500 is a replication-defective recombinant adenoviral vector containing the cloned human wild-type (normal) tumor suppressor gene p53. SCH 58500 is in trials to evaluate potential clinical utility. A series of toxicology studies in rats and mic
Autor:
Howard Y. Chen, Chennekatu P. Peter, Lea G. Stabinski, Dan Holder, Darryl H. Patrick, Srinivasa Prahalada, Richard E. Morrissey, Matthew J. van Zwieten, Georges De Burlet
Publikováno v:
Toxicologic Pathology. 26:185-200
The purpose of this study was to evaluate the pharmacological and toxicological effects of exogenous GH administration in normal adult dogs. Because porcine GH (pGH) is structurally identical to canine GH, pGH was selected for a 14-wk study in dogs.
Autor:
Melissa C. Marr, Christina B. Myers, Catherine J. Price, Bernard A. Schwetz, Richard E. Morrissey, Randolph B. Sleet, Elizabeth A. Field, Julia D. George
Publikováno v:
Teratology. 48:33-44
Diethyl phthalate (DEP) and dimethyl phthalate (DMP), phthalic acid ester (PAE) plasticizers, were evaluated for developmental toxicity because of reports in the literature that some PAE were embryotoxic and teratogenic. A previous study (Singh et al
Autor:
Susan A. Russell, Richard E. Morrissey, Sarah R. Kennedy, Dushyant K. Gulati, Leta H. Barnes, Esther Hope, Robert E. Chapin
Publikováno v:
Toxicological Sciences. 21:8-14
Are Mouse Strains Differentially Susceptible to the Reproductive Toxicity of Ethylene Glycol Monomethyl Ether? A Study of Three Strains. Chapin, R. E., Morrissey, R. E., Gulati, D. K., Hope, E., Barnes, L. H., Russell, S. A., and Kennedy, S. R. (1993
Publikováno v:
Teratology. 46:169-181
Ethylene glycol (EG), a chemical which causes skeletal malformations in rats, was administered by gavage to sperm positive CD® rats on gestational days (gd) 6 through 15 at doses of 0 or 2,500 mg/kg/day to assess its effects on the pre- and postnata
Autor:
Richard E. Morrissey, Melissa C. Marr, Carole A. Dr. Kimmel, Bernard A. Schwetz, Julia D. George, Catherine J. Price
Publikováno v:
Fundamental and Applied Toxicology. 19:238-245
Diethylene glycol dimethyl ether (diEGdiME) and triethylene glycol dimethyl ether (triEGdiME), widely used organic solvents, are structurally related to several compounds that produce reproductive and developmental toxicity, including teratogenicity
Autor:
Richard E. Morrissey, Julia D. George, Bernard A. Schwetz, Catherine J. Price, Carole A. Kimmel, Melissa C. Marr
Publikováno v:
Fundamental and Applied Toxicology. 19:15-25
Timed-pregnant CD-1 outbred Albino Swiss mice and New Zealand White rabbits were dosed by gavage with ethylene glycol diethyl ether (EGdiEE) in distilled water during major organogenesis. Mice were dosed on Gestational Days (gd) 6 through 15 (0, 50,
Autor:
Richard E. Morrissey, Catherine J. Price, Bernard A. Schwetz, Jerrold J. Heindel, Elizabeth A. Field, Melissa C. Marr, Christina B. Myers
Publikováno v:
Fundamental and Applied Toxicology. 18:266-277
Boric acid (BORA), an ingredient of many cosmetics, pharmaceuticals, and pesticides, was tested for developmental toxicity in timed-pregnant Swiss mice and Sprague-Dawley rats (n = 26-28/group). BORA (0, 0.1, 0.2, or 0.4% in feed) was provided throug
Autor:
BERNARD A. SCHWETZ, CATHERINE E. PRICE, JULIA D. GEORGE, CAROLE A. KIMMEL, RICHARD E. MORRISSEY, MELISSA C. MARR
Publikováno v:
Toxicological Sciences. 19:238-245