Zobrazeno 1 - 10
of 248
pro vyhledávání: '"RICHARD CLARKSON"'
Publikováno v:
Molecular Cancer, Vol 23, Iss 1, Pp 1-17 (2024)
Abstract In the early 1990’s a group of unrelated genes were identified from the sites of recurring translocations in B-cell lymphomas. Despite sharing the nomenclature ‘Bcl’, and an association with blood-borne cancer, these genes have unrelat
Externí odkaz:
https://doaj.org/article/6707128c3c574f31b5771f3313c2724c
Autor:
Gareth D. Healey, Belen Pan-Castillo, Jezabel Garcia-Parra, Julia Davies, Shaun Roberts, Eilir Jones, Kalyan Dhar, Sarika Nandanan, Nasima Tofazzal, Luke Piggott, Richard Clarkson, Gillian Seaton, Asa Frostell, Tim Fagge, Colin McKee, Lavinia Margarit, R. Steven Conlan, Deyarina Gonzalez
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 7, Iss 1, Pp 1-18 (2019)
Abstract Background The treatment of endometrial cancer (EC), the most common gynecological cancer, is currently hampered by the toxicity of current cytotoxic agents, meaning novel therapeutic approaches are urgently required. Methods A cohort of 161
Externí odkaz:
https://doaj.org/article/8a6b676f57f741f9b1895a074cb50d87
Autor:
Richard Clarkson, Julia Gee, Robert B. Clarke, Maria dM. Vivanco, Marco Piva, Fouad Alchami, Peter Barrett-Lee, Christine Morris, Philippa Young, Ladislav Andera, Iduna Fichtner, Michael Becker, Bruno M. Simões, Angelica Santiago-Gómez, Timothy Robinson, Andreia Silva, Luke Piggott
Figure S1: Endocrine-resistant MCF-7 cells demonstrate sensitivity to TRAIL Figure S2: Endocrine-resistant CSCs demonstrate sensitivity to TRIAL. Figure S3: Primary-derived patient samples. Figure S4: Endocrine-resistant primary and PDX tumour cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e19b7dfd3d8857d41b3de881fc5f24e
https://doi.org/10.1158/1078-0432.22465277
https://doi.org/10.1158/1078-0432.22465277
Autor:
Richard Clarkson, Julia Gee, Robert B. Clarke, Maria dM. Vivanco, Marco Piva, Fouad Alchami, Peter Barrett-Lee, Christine Morris, Philippa Young, Ladislav Andera, Iduna Fichtner, Michael Becker, Bruno M. Simões, Angelica Santiago-Gómez, Timothy Robinson, Andreia Silva, Luke Piggott
Purpose: One third of ER-positive breast cancer patients who initially respond to endocrine therapy become resistant to treatment. Such treatment failure is associated with poor prognosis and remains an area of unmet clinical need. Here, we identify
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7526ee6a04e59ea6737bd64b7ddcc74a
https://doi.org/10.1158/1078-0432.c.6525980
https://doi.org/10.1158/1078-0432.c.6525980
Autor:
David W. Hedley, Lars-Christian Horn, Roya Navab, Nikolina Radulovich, Richard Clarkson, Jinzi Zheng, Mary Ping-Jiang Cao, Neesha Dhani, Joerg Schwock
Supplementary Information from Targeting Focal Adhesion Kinase with Dominant-Negative FRNK or Hsp90 Inhibitor 17-DMAG Suppresses Tumor Growth and Metastasis of SiHa Cervical Xenografts
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c0c53925a60a8fb127a2473447f85eb
https://doi.org/10.1158/0008-5472.22377104.v1
https://doi.org/10.1158/0008-5472.22377104.v1
Autor:
David W. Hedley, Lars-Christian Horn, Roya Navab, Nikolina Radulovich, Richard Clarkson, Jinzi Zheng, Mary Ping-Jiang Cao, Neesha Dhani, Joerg Schwock
Supplementary Figures 1-9 from Targeting Focal Adhesion Kinase with Dominant-Negative FRNK or Hsp90 Inhibitor 17-DMAG Suppresses Tumor Growth and Metastasis of SiHa Cervical Xenografts
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41bdc5de2f9e124fe115d4ea8744e724
https://doi.org/10.1158/0008-5472.22377107
https://doi.org/10.1158/0008-5472.22377107
Publikováno v:
Insurance Insider. 4/8/2024, pN.PAG-N.PAG. 1p.
Publikováno v:
Shoulder Elbow
Background Pectoralis minor syndrome involves pain, paraesthesia and weakness in the arm due to compression of the brachial plexus passing beneath pectoralis minor; this paper reports the results of a single centre’s treatment pathway in affected p
Autor:
Łukasz, Kiraga, Gabriele, Cerutti, Agata, Braniewska, Damian, Strzemecki, Zuzanna, Sas, Alberto, Boffi, Carmelinda, Savino, Linda Celeste, Montemiglio, Daniel, Turnham, Gillian, Seaton, Alessandra, Bonamore, Richard, Clarkson, Adam M, Dabkowski, Stephen J, Paisey, Bartłomiej, Taciak, Paulina, Kucharzewska, Tomasz P, Rygiel, Magdalena, Król
Publikováno v:
International Journal of Molecular Sciences
Proteins, as a major component of organisms, are considered the preferred biomaterials for drug delivery vehicles. Hemoglobin (Hb) has been recently rediscovered as a potential drug carrier, but its use for biomedical applications still lacks extensi
Autor:
Richard Clarkson
Publikováno v:
Breast Cancer Management. 3:237-240
ISSN 1758-1923 Breast Cancer Manage. (2014) 3(3), 237–240 Q What led you to specialize in the field of breast cancer stem cell research? It was almost by accident. Approximately 6 years ago, two of my graduate students, Alison Wakefield and Luke Pi