Zobrazeno 1 - 10
of 4 718 215
pro vyhledávání: '"RICHARD A."'
Autor:
Michiel Vanneste, Hanne Hoskens, Seppe Goovaerts, Harold Matthews, Jay Devine, Jose D. Aponte, Joanne Cole, Mark Shriver, Mary L. Marazita, Seth M. Weinberg, Susan Walsh, Stephen Richmond, Ophir D. Klein, Richard A. Spritz, Hilde Peeters, Benedikt Hallgrímsson, Peter Claes
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract Human craniofacial shape is highly variable yet highly heritable with numerous genetic variants interacting through multiple layers of development. Here, we hypothesize that Mendelian phenotypes represent the extremes of a phenotypic spectru
Externí odkaz:
https://doaj.org/article/53249a4e52054d56af916527ff5bdc39
Autor:
Moez Dawood, Shawn Fayer, Sriram Pendyala, Mason Post, Divya Kalra, Karynne Patterson, Eric Venner, Lara A. Muffley, Douglas M. Fowler, Alan F. Rubin, Jennifer E. Posey, Sharon E. Plon, James R. Lupski, Richard A. Gibbs, Lea M. Starita, Carla Daniela Robles-Espinoza, Willow Coyote-Maestas, Irene Gallego Romero
Publikováno v:
Genome Medicine, Vol 16, Iss 1, Pp 1-16 (2024)
Abstract Background Multiplexed Assays of Variant Effects (MAVEs) can test all possible single variants in a gene of interest. The resulting saturation-style functional data may help resolve variant classification disparities between populations, esp
Externí odkaz:
https://doaj.org/article/7bb11a609b814018b3cd0242b8aad730
Autor:
Beth E. Meyerson, Linnea B. Linde-Krieger, Gregory A. Carter, Allison J. Huff, Benjamin R. Brady, Richard A. Crosby, Jennifer De La Rosa, Allie Allison, Mohammad Barakat, Michael Pava, Mark Schaefer
Publikováno v:
Addiction Science & Clinical Practice, Vol 19, Iss 1, Pp 1-14 (2024)
Abstract Background U.S. policy intervention to increase methadone treatment accommodations during COVID did not result in national adoption of the new patient-centered treatment practices. Staff-level interventions may facilitate adoption of these t
Externí odkaz:
https://doaj.org/article/5f76d2993c7e4eb3908b369eaf3e9dd0
Autor:
Thu T. Tran, Jonathan Davies, Richard A. Johnston, Harry Karmouty-Quintana, Huiling Li, Caroline E. Crocker, Amir M. Khan, Joseph L. Alcorn
Publikováno v:
BMC Pulmonary Medicine, Vol 24, Iss 1, Pp 1-17 (2024)
Abstract Background Prolonged exposure to hyperoxia can lead to hyperoxic acute lung injury (HALI) in preterm neonates. Vitamin D (VitD) stimulates lung maturation and acts as an anti-inflammatory agent. Our objective was to determine if VitD provide
Externí odkaz:
https://doaj.org/article/801a9597a68b4ebfa2bb329ddd5ab9c6
Autor:
Rachel F. Ainsworth, Lauren H. Vickers, Jonathan D. Bolland, Marie J. Taylor, Jon P. Harvey, Richard A. A. Noble, Ian G. Cowx, Andy D. Nunn
Publikováno v:
Scientific Data, Vol 11, Iss 1, Pp 1-7 (2024)
Abstract Long-term datasets provide context and understanding of complex ecological processes, including temporal variations in species diversity and ecosystem dynamics. This dataset is comprised of body length measurements (mm) of more than 380,000
Externí odkaz:
https://doaj.org/article/f7d47231a9ce4e54af91d83065bb1f09
Autor:
Bin Wan, Amin Saberi, Casey Paquola, H. Lina Schaare, Meike D. Hettwer, Jessica Royer, Alexandra John, Lena Dorfschmidt, Şeyma Bayrak, Richard A. I. Bethlehem, Simon B. Eickhoff, Boris C. Bernhardt, Sofie L. Valk
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract The human cerebral cortex shows hemispheric asymmetry, yet the microstructural basis of this asymmetry remains incompletely understood. Here, we probe layer-specific microstructural asymmetry using one post-mortem male brain. Overall, anteri
Externí odkaz:
https://doaj.org/article/e06149ddaf824232bd40b434b10e857d
Autor:
Yuka Takemon, Erin D. Pleasance, Alessia Gagliardi, Christopher S. Hughes, Veronika Csizmok, Kathleen Wee, Diane L. Trinh, Ryan D. Huff, Andrew J. Mungall, Richard A. Moore, Eric Chuah, Karen L. Mungall, Eleanor Lewis, Jessica Nelson, Howard J. Lim, Daniel J. Renouf, Steven JM. Jones, Janessa Laskin, Marco A. Marra
Publikováno v:
Genome Medicine, Vol 16, Iss 1, Pp 1-31 (2024)
Abstract Background Loss-of-function (LOF) alterations in tumour suppressor genes cannot be directly targeted. Approaches characterising gene function and vulnerabilities conferred by such mutations are required. Methods Here, we computationally map
Externí odkaz:
https://doaj.org/article/2954f6a10f424393a3fd559481966131
Autor:
Melissa A. Greenwald, Hussein Ezzeldin, Emily A. Blumberg, Barbee I. Whitaker, Richard A. Forshee
Publikováno v:
Health Research Policy and Systems, Vol 22, Iss 1, Pp 1-13 (2024)
Abstract Background The transplantation of human organs, and some human tissues, is often the only life-saving therapy available for serious and life-threatening congenital, inherited or acquired diseases. However, it is associated with a risk of tra
Externí odkaz:
https://doaj.org/article/3116c84a2d2642c0bc51caef1d5aa522
Autor:
Lindsay N. Carpp, Ollivier Hyrien, Youyi Fong, David Benkeser, Sanne Roels, Daniel J. Stieh, Ilse Van Dromme, Griet A. Van Roey, Avi Kenny, Ying Huang, Marco Carone, Adrian B. McDermott, Christopher R. Houchens, Karen Martins, Lakshmi Jayashankar, Flora Castellino, Obrimpong Amoa-Awua, Manjula Basappa, Britta Flach, Bob C. Lin, Christopher Moore, Mursal Naisan, Muhammed Naqvi, Sandeep Narpala, Sarah O’Connell, Allen Mueller, Leo Serebryannyy, Mike Castro, Jennifer Wang, Christos J. Petropoulos, Alex Luedtke, Yiwen Lu, Chenchen Yu, Michal Juraska, Nima S. Hejazi, Daniel N. Wolfe, Jerald Sadoff, Glenda E. Gray, Beatriz Grinsztejn, Paul A. Goepfert, Linda-Gail Bekker, Aditya H. Gaur, Valdilea G. Veloso, April K. Randhawa, Michele P. Andrasik, Jenny Hendriks, Carla Truyers, An Vandebosch, Frank Struyf, Hanneke Schuitemaker, Macaya Douoguih, James G. Kublin, Lawrence Corey, Kathleen M. Neuzil, Dean Follmann, Richard A. Koup, Ruben O. Donis, Peter B. Gilbert, On behalf of the Immune Assays Team, the Coronavirus Vaccine Prevention Network (CoVPN)/ENSEMBLE Team, the United States Government (USG)/CoVPN Biostatistics Team
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract Assessment of immune correlates of severe COVID-19 has been hampered by the low numbers of severe cases in COVID-19 vaccine efficacy (VE) trials. We assess neutralizing and binding antibody levels at 4 weeks post-Ad26.COV2.S vaccination as c
Externí odkaz:
https://doaj.org/article/e3fbd928bb5b421b95c9d27047187105
Autor:
Michael O’Sullivan, Stephen Sitch, Pierre Friedlingstein, Ingrid T. Luijkx, Wouter Peters, Thais M. Rosan, Almut Arneth, Vivek K. Arora, Naveen Chandra, Frédéric Chevallier, Philippe Ciais, Stefanie Falk, Liang Feng, Thomas Gasser, Richard A. Houghton, Atul K. Jain, Etsushi Kato, Daniel Kennedy, Jürgen Knauer, Matthew J. McGrath, Yosuke Niwa, Paul I. Palmer, Prabir K. Patra, Julia Pongratz, Benjamin Poulter, Christian Rödenbeck, Clemens Schwingshackl, Qing Sun, Hanqin Tian, Anthony P. Walker, Dongxu Yang, Wenping Yuan, Xu Yue, Sönke Zaehle
Publikováno v:
Communications Earth & Environment, Vol 5, Iss 1, Pp 1-10 (2024)
Abstract Northern forests are an important carbon sink, but our understanding of the driving factors is limited due to discrepancies between dynamic global vegetation models (DGVMs) and atmospheric inversions. We show that DGVMs simulate a 50% lower
Externí odkaz:
https://doaj.org/article/6cb79a6d3efd4c0ebb93f32fee4b6109