Zobrazeno 1 - 2
of 2
pro vyhledávání: '"RHIM, RIP homotypic interaction motif"'
Publikováno v:
Seminars in Cell & Developmental Biology
Receptor Interacting Protein Kinases (RIPKs) are cellular signaling molecules that are critical for homeostatic signaling in both communicable and non-communicable disease processes. In particular, RIPK1, RIPK2, RIPK3 and RIPK7 have emerged as key me
Autor:
Ling Shao, Zhang-Xu Liu, Janet Kwok, Katherine Donovan, Brian T. Lee, Andrea Iorga, Layla Shojaie, Heather S. Johnson, Lily Dara, Mariam Aghajan, Jo Suda
Publikováno v:
The Journal of Biological Chemistry
Acetaminophen (APAP)-induced liver necrosis is a form of regulated cell death (RCD) in which APAP activates the mitogen-activated protein kinases (MAPKs) and specifically the c-Jun-N-terminal kinase (JNK) pathway, leading to necrotic cell death. Prev