Zobrazeno 1 - 10
of 1 021
pro vyhledávání: '"RGD motif"'
Publikováno v:
International Journal Bioautomation, Vol 28, Iss 1, Pp 59-67 (2024)
In the present work, we have investigated a novel recombinant cystatin dgECP1 and its mutant form, dgECP1m1, focused on their impact on the adhesive behaviour of two breast cell lines: the cancerous, MDA-MB-231, and the normal, MCF-10A. DgECP1 cystat
Externí odkaz:
https://doaj.org/article/279eeb0b30894848b7103e5c0fe3f2d7
Publikováno v:
Iranian Journal of Basic Medical Sciences, Vol 24, Iss 6, Pp 734-743 (2021)
Objective(s): Fibrosis is the major cause of chronic kidney injury and the primary etiology in diabetic glomerulosclerosis. The initial study of protein hydrolysate of green peas hydrolyzed by bromelain (PHGPB) considered it to improve kidney functio
Externí odkaz:
https://doaj.org/article/ac2e961e13124590bfbb0f89dd00e456
Autor:
Christopher A. Beaudoin, Emmanouela Petsolari, Samir W. Hamaia, Sharif Hala, Fadwa S. Alofi, Arun P. Pandurangan, Tom L. Blundell, Sundeep Chaitanya Vedithi, Christopher L.-H. Huang, Antony P. Jackson
Publikováno v:
Biochemical and Biophysical Research Communications. 666:61-67
The RGD motif on the SARS-CoV-2 spike protein has been suggested to interact with RGD-binding integrins αVβ3 and α5β1 to enhance viral cell entry and alter downstream signaling cascades. The D405N mutation on the Omicron subvariant spike proteins
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33106946ebb34dbf0d56168230eb7b09
https://doi.org/10.1016/j.bbrc.2023.04.088
https://doi.org/10.1016/j.bbrc.2023.04.088
Autor:
Cristina Manferdini, Diego Trucco, Yasmin Saleh, Elena Gabusi, Paolo Dolzani, Enrico Lenzi, Lorenzo Vannozzi, Leonardo Ricotti, Gina Lisignoli
Publikováno v:
Gels, Vol 8, Iss 6, p 382 (2022)
Articular cartilage is known to have limited intrinsic self-healing capacity when a defect or a degeneration process occurs. Hydrogels represent promising biomaterials for cell encapsulation and injection in cartilage defects by creating an environme
Externí odkaz:
https://doaj.org/article/14e668506ef1488281c467583133013a
Autor:
Gitanjali Asampille, Brijesh Kumar Verma, Monalisa Swain, Abhijith Shettar, Steven A. Rosenzweig, Paturu Kondaiah, Hanudatta S. Atreya
Publikováno v:
Journal of Nanobiotechnology, Vol 16, Iss 1, Pp 1-14 (2018)
Abstract We introduce a self-assembling polypeptide-based nanotube system having the ability to specifically target cancer cells. The nanotubes target the cancer cell surface through integrin engagement with the help of multiple RGD units present alo
Externí odkaz:
https://doaj.org/article/270270e956a64bf39492e5c382795da6
Autor:
Danielle Nader, Steve W. Kerrigan
Publikováno v:
Viruses, Vol 14, Iss 5, p 891 (2022)
The vascular barrier is heavily injured following SARS-CoV-2 infection and contributes enormously to life-threatening complications in COVID-19. This endothelial dysfunction is associated with the phlogistic phenomenon of cytokine storms, thrombotic
Externí odkaz:
https://doaj.org/article/c7375034f8184eda9fa321ea7c1abf42
Autor:
Antonella Bugatti, Federica Filippini, Marta Bardelli, Alberto Zani, Paola Chiodelli, Serena Messali, Arnaldo Caruso, Francesca Caccuri
Publikováno v:
Viruses, Vol 14, Iss 4, p 705 (2022)
Integrins represent a gateway of entry for many viruses and the Arg-Gly-Asp (RGD) motif is the smallest sequence necessary for proteins to bind integrins. All Severe Acute Respiratory Syndrome Virus type 2 (SARS-CoV-2) lineages own an RGD motif (aa 4
Externí odkaz:
https://doaj.org/article/694de9f5b0214413a77964f098dc9d89
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