Loss-of-function FLG mutations are associated with reduced history of acne vulgaris in a cohort of patients with atopic eczema of Bangladeshi ancestry in East London.

Autor: Hughes AJ; Queen Mary University of London Centre for Cell Biology and Cutaneous Research, London, UK.; Department of Dermatology, Barts Health NHS Trust, London, UK., Barbosa E; Department of Dermatology, Barts Health NHS Trust, London, UK., Cernova J; Department of Dermatology, Barts Health NHS Trust, London, UK., Thomas BR; Queen Mary University of London Centre for Cell Biology and Cutaneous Research, London, UK., O'Shaughnessy RFL; Queen Mary University of London Centre for Cell Biology and Cutaneous Research, London, UK., O'Toole EA; Queen Mary University of London Centre for Cell Biology and Cutaneous Research, London, UK.; Department of Dermatology, Barts Health NHS Trust, London, UK.

Publikováno v: Clinical and experimental dermatology [Clin Exp Dermatol] 2024 Nov 22; Vol. 49 (12), pp. 1547-1553.

Chronic activation of Toll-like receptor 2 induces an ichthyotic skin phenotype.

Autor: Tagoe H; Centre for Cell Biology and Cutaneous Research, Queen Mary University of London, London, UK.; Livingstone Skin Research Centre., Hassan S; Centre for Cell Biology and Cutaneous Research, Queen Mary University of London, London, UK.; Livingstone Skin Research Centre., Bliss E; Department of Genetics and Genomic Medicine., Youssef G; Centre for Cell Biology and Cutaneous Research, Queen Mary University of London, London, UK.; Livingstone Skin Research Centre., Heywood W; Department of Genetics and Genomic Medicine., Mills K; Department of Genetics and Genomic Medicine., Harper JI; Livingstone Skin Research Centre.; Department of Immunobiology and Dermatology, UCL Great Ormond Street Institute of Child Health, London, UK., O'Shaughnessy RFL; Centre for Cell Biology and Cutaneous Research, Queen Mary University of London, London, UK.

Publikováno v: The British journal of dermatology [Br J Dermatol] 2023 Jul 07; Vol. 189 (1), pp. 91-102.

Ceramide kinase-like protein, 'the kinase that isn't', finds a role in skin cancer stress relief.

Autor: O'Shaughnessy RFL; Centre for Cell Biology and Cutaneous Research, Blizard Institute, Queen Mary University of London, London, UK.

Publikováno v: The British journal of dermatology [Br J Dermatol] 2021 Jul; Vol. 185 (1), pp. 14-15. Date of Electronic Publication: 2021 Mar 23.

Akt1-associated actomyosin remodelling is required for nuclear lamina dispersal and nuclear shrinkage in epidermal terminal differentiation.

Autor: Rogerson C; Centre for Cell Biology and Cutaneous Research, Blizard Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK., Wotherspoon DJ; Centre for Cell Biology and Cutaneous Research, Blizard Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK., Tommasi C; Immunobiology and Dermatology, UCL Great Ormond Street Institute of Child Health, London, UK.; School of Cellular & Molecular Medicine, University of Bristol, Bristol, UK., Button RW; Centre for Cell Biology and Cutaneous Research, Blizard Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK., O'Shaughnessy RFL; Centre for Cell Biology and Cutaneous Research, Blizard Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK. r.f.l.oshaughnessy@qmul.ac.uk.

Publikováno v: Cell death and differentiation [Cell Death Differ] 2021 Jun; Vol. 28 (6), pp. 1849-1864. Date of Electronic Publication: 2021 Jan 18.

Perspective: Controlling Epidermal Terminal Differentiation with Transcriptional Bursting and RNA Bodies.

Autor: Wotherspoon D; Centre for Cell Biology and Cutaneous Research, Blizard Institute, Queen Mary University of London, London E1 2AT, UK., Rogerson C; The Francis Crick Institute, London NW1 1AT, UK., O'Shaughnessy RFL; Centre for Cell Biology and Cutaneous Research, Blizard Institute, Queen Mary University of London, London E1 2AT, UK.

Publikováno v: Journal of developmental biology [J Dev Biol] 2020 Dec 04; Vol. 8 (4). Date of Electronic Publication: 2020 Dec 04.