Zobrazeno 1 - 10
of 169
pro vyhledávání: '"RET-rearrangement"'
Autor:
Chunyue Wang, Zhenlong Zhang, Yulan Sun, Song Wang, Mengmeng Wu, Qiuxiang Ou, Yang Xu, Zhiming Chen, Yang Shao, Hong Liu, Peifeng Hou
Publikováno v:
Journal of Translational Medicine, Vol 20, Iss 1, Pp 1-13 (2022)
Abstract Background RET fusions are rare oncogenic drivers in non-small cell lung cancer (NSCLC). While activating RET rearrangements are found in NSCLC patients harboring epidermal growth factor receptor (EGFR) genetic alterations at resistance to E
Externí odkaz:
https://doaj.org/article/600f7d90e0714d1baf7455f341e10ef6
Autor:
Qing-Yun Gao, Fa-Man Xiao, Xiao-Cheng Lin, Yu-Qing Chen, Yu-Fa Li, Chang Lu, Jun-Wei Su, Quan-Quan Tan, Chan-Yuan Zhang, Jiao Yang, Yi-Long Wu, Hua-Jun Chen, Jin-Ji Yang
Publikováno v:
Cancer Treatment and Research Communications, Vol 35, Iss , Pp 100707- (2023)
Background: For patients with lung malignancies with RET rearrangement, the efficacy of immune checkpoint inhibitors is limited. The characteristics of the tumour immune microenvironment (TIME) and molecular pathological features of these patients ha
Externí odkaz:
https://doaj.org/article/023d31908c7f494ca5ccddf450d9803c
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
PurposeTo create an ultrasound -based deep learning radiomics nomogram (DLRN) for preoperatively predicting the presence of RET rearrangement among patients with papillary thyroid carcinoma (PTC).MethodsWe retrospectively enrolled 650 patients with P
Externí odkaz:
https://doaj.org/article/1de21bbcc31742e28de729b1803eb5fb
Autor:
Margherita Nannini, Andrea Repaci, Gianluca Ricco, Manuela Ianni, Arber Golemi, Vincenzo Maiolo, Marco Ferrari, Filippo Natali, Elisa Lodi Rizzini, Fabio Monari, Erica Solaroli, Antonio De Leo, Thais Maloberti, Maria A. Pantaleo, Dario De Biase, Giovanni Tallini
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
We are recently faced with a progressive evolution of the therapeutic paradigm for radioiodine refractory differentiated thyroid cancer (RAI-R DTC), since the advent of tissue agnostic inhibitors. Thus, tumor genotype assessment is always more releva
Externí odkaz:
https://doaj.org/article/49cd3f8164ad45bf8f469eaab1aeaaa6
Akademický článek
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Autor:
Chang Lu, Xiao-Rong Dong, Jun Zhao, Xu-Chao Zhang, Hua-Jun Chen, Qing Zhou, Hai-Yan Tu, Xing-Hao Ai, Xiao-Feng Chen, Gai-Li An, Jun Bai, Jin-Lu Shan, Yi-Na Wang, Shuan-Ying Yang, Xiang Liu, Wu Zhuang, Hui-Ta Wu, Bo Zhu, Xue-Feng Xia, Rong-Rong Chen, De-Jian Gu, Hua-Min Xu, Yi-Long Wu, Jin-Ji Yang
Publikováno v:
Journal of Hematology & Oncology, Vol 13, Iss 1, Pp 1-12 (2020)
Abstract Background Rearranged during transfection (RET) has been proven to be a tumorigenic target in non-small cell lung cancers (NSCLCs). In RET-rearranged NSCLCs, molecular features and their impact on prognosis were not well illustrated, and the
Externí odkaz:
https://doaj.org/article/65892830cd4a4799975b53c363390d15
Akademický článek
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Akademický článek
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Publikováno v:
The Oncologist. 28:402-413
The objective of this narrative review is to summarize the efficacy and safety of available therapies for rearranged during transfection (RET) fusion-positive non-small cell lung cancer (NSCLC), including in patients with central nervous system (CNS)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4320214acf4bc18a9598481627651b2
https://doi.org/10.1093/oncolo/oyac264
https://doi.org/10.1093/oncolo/oyac264
Autor:
Luis Mendoza
Publikováno v:
Oncology Reviews, Vol 12, Iss 2 (2018)
Precision oncology is now the evidence-based standard of care for the management of many advanced non-small cell lung cancers (NSCLC). Notably, new molecular profiling technologies have permitted dynamic growth in the identification of actionable dri
Externí odkaz:
https://doaj.org/article/e00317a8531945d3b1fa478ff3d6827f