Výsledky vyhledávání - "RES, reticuloendothelial system"

Delivery strategies of amphotericin B for invasive fungal infections

Autor: Jun Wu, Li-Fang Fan, Zongmin Zhao, Imran Shair Mohammad, Lifang Yin, Xiaochun Wang, Zhongjian Chen, Marwa Ahmed Sallam, Wei He, Nurunnabi

Publikováno v: Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica B, Vol 11, Iss 8, Pp 2585-2604 (2021)

Invasive fungal infections (IFIs) represent a growing public concern for clinicians to manage in many medical settings, with substantial associated morbidities and mortalities. Among many current therapeutic options for the treatment of IFIs, amphote

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::422a502aeaaad20f2253c2f7645ad654
https://doi.org/10.1016/j.apsb.2021.04.010

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Recent advances in nanomedicines for the treatment of ischemic stroke

Autor: Chao Li, Chen Jiang, Tao Sun

Publikováno v: Acta Pharmaceutica Sinica B, Vol 11, Iss 7, Pp 1767-1788 (2021)
Acta Pharmaceutica Sinica. B

Ischemic stroke is a cerebrovascular disease normally caused by interrupted blood supply to the brain. Ischemia would initiate the cascade reaction consisted of multiple biochemical events in the damaged areas of the brain, where the ischemic cascade

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f69f164eb91d122d8129e948fdf80fcb
http://www.sciencedirect.com/science/article/pii/S2211383520308194

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Receptor-mediated targeted drug delivery systems for treatment of inflammatory bowel disease: Opportunities and emerging strategies

Autor: Caifang Gao, Peng Liu, Hongguo Chen, Xu Wu, Xudong Tang, Yitao Wang, Chi Teng Vong, Shengpeng Wang

Publikováno v: Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica B, Vol 11, Iss 9, Pp 2798-2818 (2021)

Inflammatory bowel disease (IBD) is a chronic intestinal disease with painful clinical manifestations and high risks of cancerization. With no curative therapy for IBD at present, the development of effective therapeutics is highly advocated. Drug de

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::caf33f667c4f81b143c5ccef5cfb99fc
http://europepmc.org/articles/PMC8463263

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Biomimetic carbon nanotubes for neurological disease therapeutics as inherent medication

Autor: Chenyang Xiang, Weisheng Guo, Yuxuan Zhang, Xing-Jie Liang

Publikováno v: Acta Pharmaceutica Sinica B, Vol 10, Iss 2, Pp 239-248 (2020)
Acta Pharmaceutica Sinica. B

Nowadays, nanotechnology is revolutionizing the approaches to different fields from manufacture to health. Carbon nanotubes (CNTs) as promising candidates in nanomedicine have great potentials in developing novel entities for central nervous system p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::733fff34f30ef2de86219e20aec8517f
http://www.sciencedirect.com/science/article/pii/S2211383519306069

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Transformative hyaluronic acid-based active targeting supramolecular nanoplatform improves long circulation and enhances cellular uptake in cancer therapy

Autor: Qingsong Li, Yongjun Wang, Lu Zhong, Dongyang Zhao, Huicong Zhang, Haotian Zhang, Yanying Liu, Qiming Kan, Jin Sun, Zhonggui He, Zhenbao Li, Lu Xu

Publikováno v: Acta Pharmaceutica Sinica B, Vol 9, Iss 2, Pp 397-409 (2019)
Acta Pharmaceutica Sinica. B

Hyaluronic acid (HA) is a natural ligand of tumor-targeted drug delivery systems (DDS) due to the relevant CD44 receptor overexpressed on tumor cell membranes. However, other HA receptors (HARE and LYVE-1) are also overexpressing in the reticuloendot

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d47596fcd524f1ecab41039b61b1e10
http://www.sciencedirect.com/science/article/pii/S2211383518306841

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Red blood cell membrane-camouflaged nanoparticles: a novel drug delivery system for antitumor application

Autor: Xuefeng Hou, Nianping Feng, Zhe Li, Qing Xia, Yongtai Zhang

Publikováno v: Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica B, Vol 9, Iss 4, Pp 675-689 (2019)

Erythrocytes (red blood cells, RBCs) are the most abundant circulating cells in the blood and have been widely used in drug delivery systems (DDS) because of their features of biocompatibility, biodegradability, and long circulating half-life. Accord

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0114f126bb7f05846b43a30dd847397c
http://europepmc.org/articles/PMC6663920

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A review of existing strategies for designing long-acting parenteral formulations: Focus on underlying mechanisms, and future perspectives

Autor: Xiangyu Wang, An Lu, Qiang Zhang, Zakia Belhadj, Yujie Shi, Jiancheng Wang

Publikováno v: Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica B, Vol 11, Iss 8, Pp 2396-2415 (2021)

The need for long-term treatments of chronic diseases has motivated the widespread development of long-acting parenteral formulations (LAPFs) with the aim of improving drug pharmacokinetics and therapeutic efficacy. LAPFs have been proven to extend t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68ae988908ab95b495e6190ff9a49114
https://pubmed.ncbi.nlm.nih.gov/34522592

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Small interfering RNA for cancer treatment: overcoming hurdles in delivery

Autor: Alaa A. A. Aljabali, Nitin Charbe, Poonam Negi, Nikhil D. Amnerkar, Gaurav Gupta, B. Ramesh, Meenu Metha, Hamid A. Bakshi, Dinesh Kumar Chellappan, Saurabh C. Khadse, Garima Shrivastava, Saurabh Satija, Kamal Dua, Flavia C. Zacconi, Murtaza M. Tambuwala, Rajendran Satheeshkumar

Publikováno v: Acta Pharmaceutica Sinica. B

In many ways, cancer cells are different from healthy cells. A lot of tactical nano-based drug delivery systems are based on the difference between cancer and healthy cells. Currently, nanotechnology-based delivery systems are the most promising tool

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2071f422f1c1f8a688b18780d3afbc9c
https://pubmed.ncbi.nlm.nih.gov/33304780

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Biomacromolecules as carriers in drug delivery and tissue engineering

Autor: Chen Jiang, Yujie Zhang, Tao Sun

Publikováno v: Acta Pharmaceutica Sinica B, Vol 8, Iss 1, Pp 34-50 (2018)
Acta Pharmaceutica Sinica. B

Natural biomacromolecules have attracted increased attention as carriers in biomedicine in recent years because of their inherent biochemical and biophysical properties including renewability, nontoxicity, biocompatibility, biodegradability, long blo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7426b5efae73e9c0099c0a65c0e2aa0
http://www.sciencedirect.com/science/article/pii/S2211383517302812

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