Zobrazeno 1 - 10
of 282
pro vyhledávání: '"REINHARD G. BRETZEL"'
Publikováno v:
PLoS ONE, Vol 4, Iss 11 (2009)
Externí odkaz:
https://doaj.org/article/2ed390fc5edc4c0cb7eb6d79ecd49e3c
Autor:
André Kidszun, Darius Schneider, Doris Erb, Gundula Hertl, Veronika Schmidt, Michael Eckhard, Klaus T. Preissner, Georg Breier, Reinhard G. Bretzel, Thomas Linn M.D., Ph.D
Publikováno v:
Cell Transplantation, Vol 15 (2006)
The formation of a new microvasculature is essential for the long-term survival and function of the islet graft. In this study we examined endothelium of isolated pancreatic islets by stimulation with growth factors, different culture conditions, and
Externí odkaz:
https://doaj.org/article/5460bdfe645c45898d948433aad64cf1
Autor:
Daniel Brandhorst, Vidya Kumarasamy, Adel Maatoui, Alexandra Alt, Reinhard G. Bretzel, Heide Brandhorst
Publikováno v:
Cell Transplantation, Vol 15 (2006)
During the isolation procedure and after transplantation islets are subjected to numerous variables associated with the induction of apoptosis. The present study investigated the effect of transient pretreatment with caspase inhibitors on function an
Externí odkaz:
https://doaj.org/article/13149040483647e9aec9974b8d16e476
Autor:
Daniel Brandhorst Ph.D., Heide Brandhorst, Vidya Kumarasamy, Adel Maataoui, Alexandra Alt, Mathias D. Brendel, Reinhard G. Bretzel
Publikováno v:
Cell Transplantation, Vol 12 (2003)
The induction of heat shock proteins (HSP) protects isolated islet cells against the cytotoxicity of inflammatory mediators in vitro. Very little information is available about the effect of HSP overexpression on function of preconditioned islet graf
Externí odkaz:
https://doaj.org/article/ea7b4a317c8e44f5b7eb74da119fa440
Autor:
Thomas Linn M.D., Doris Erb, Darius Schneider, Andre Kidszun, A. Eser Elçin, Reinhard G. Bretzel, Y. Murat Elçin
Publikováno v:
Cell Transplantation, Vol 12 (2003)
One of the major obstacles in transplanting avascular tissue or metabolically active cells for ischemic diseases is the loss of transplanted cells due to lack of oxygen and nutrients in the early posttransplantation period. Biodegradable polymeric ti
Externí odkaz:
https://doaj.org/article/834bc795020d40169667f5fd8c1be99c
Publikováno v:
Cell Transplantation, Vol 11 (2002)
The objective of this study was to define pretransplant islet culture conditions for optimum tissue engraftment in the rat islet allotransplantation model. Lewis rat islets were cultured in TCM 199/5% fetal calf serum for 1 day at 37°C, followed by
Externí odkaz:
https://doaj.org/article/4c58b722df8f4633a5f20d44d08bc0c3
Autor:
Daniel Brandhorst Ph.D., Hans-Peter Hammes, Heide Brandhorst, Anke Zwolinski, Fariborz Nahidi, Alexandra Alt, Reinhard G. Bretzel
Publikováno v:
Cell Transplantation, Vol 9 (2000)
The heat-induced HSP-70 expression protects rat islet single cells against lysis mediated by nitric oxide (NO), reactive oxygen, and streptozotocin. The present study was performed to investigate the potential antiinflammatory effect of pretransplant
Externí odkaz:
https://doaj.org/article/ca7f120e767c4dd4b168ef2d8d84de63
Autor:
Heide Brandhorst, Daniel Brandhorst, Mathias D. Brendel, Bernhard J. Hering, Reinhard G. Bretzel
Publikováno v:
Cell Transplantation, Vol 7 (1998)
This study investigated the recovery of pancreatic insulin content during human islet isolation prior to and after digestion-filtration, continuous Hanks-Ficoll gradient purification ( n = 20), and 3–4 day culture at 22°C ( n = 6). The native insu
Externí odkaz:
https://doaj.org/article/3f943e53cac54cd0b0f0359174be733f
Autor:
Gerd Klöck, Matthias B. Kowalski, Bernhard J. Hering, Martin E. Eiden, Astrid Weidemann, Stefan Langer, Ulrich Zimmermann, Konrad Federlin, Reinhard G. Bretzel
Publikováno v:
Cell Transplantation, Vol 5 (1996)
Transplantation of isolated islets of Langerhans is an intriguing possibility for the treatment of diabetes mellitus. The isolation of islets from pancreata requires the specific dissociation of the tissue. Commercial collagenases from Clostridium hi
Externí odkaz:
https://doaj.org/article/382a4468e4fb47f89033831956f1da05
Autor:
Derek LeRoith, Luc Van Gaal, Guntram Schernthaner, Matthew C. Riddle, Stefano Del Prato, Clifford J. Bailey, Reinhard G. Bretzel, Itamar Raz, William T. Cefalu, Philip Home
Publikováno v:
Diabetes Care
Diabetes care
Diabetes care
Given the continued interest in defining the optimal management of individuals with type 2 diabetes, the Editor of Diabetes Care convened a working party of diabetes specialists to examine this topic in the context of insulin therapy. This was prompt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea48aecb0687db56b30878765bcdff8b
http://europepmc.org/articles/PMC5131884
http://europepmc.org/articles/PMC5131884