Zobrazeno 1 - 7
of 7
pro vyhledávání: '"REIJA RANDÉN-BRADY"'
Autor:
Reija Randén-Brady, Timo Carpén, Laura C. Hautala, Tuomas Tolvanen, Caj Haglund, Sakari Joenväärä, Petri Mattila, Antti Mäkitie, Sanna Lehtonen, Jaana Hagström, Suvi Silén
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract The increasing incidence of oropharyngeal squamous cell carcinoma (OPSCC) is primarily due to human papillomavirus, and understanding the tumor biology caused by the virus is crucial. Our goal was to investigate the proteins present in the s
Externí odkaz:
https://doaj.org/article/e6c8f9fd31ce44a6ac369bb73e9689a6
Autor:
Amy Dickinson, Mayank Saraswat, Stina Syrjänen, Tiialotta Tohmola, Robert Silén, Reija Randén-Brady, Timo Carpén, Jaana Hagström, Caj Haglund, Petri Mattila, Antti Mäkitie, Sakari Joenväärä, Suvi Silén
Publikováno v:
PLoS ONE, Vol 15, Iss 6, p e0233974 (2020)
BackgroundThe surrogate immunohistochemical marker, p16INK4a, is used in clinical practice to determine the high-risk human papillomavirus (HPV) status of oropharyngeal squamous cell carcinomas (OPSCC). With a specificity of 83%, this will misclassif
Externí odkaz:
https://doaj.org/article/3102e6c378c849ca9c6bfa6b280948e7
Autor:
ANNA KAISA KYLMÄ, TIMO SORSA, LAURI JOUHI, HARRI K. MUSTONEN, HESHAM MOHAMED, REIJA RANDÉN-BRADY, ANTTI MÄKITIE, TIMO ATULA, JAANA HAGSTRÖM, CAJ HAGLUND
Publikováno v:
Anticancer Research. 42:5415-5430
Background/Aim: The oral bacteria involved in the development of periodontitis alter the tissue conditions and modify immune responses in a way that may also influence tumor development. We investigated the prevalence of R gingipain (Rgp), a key viru
Autor:
Anna Kaisa, Kylmä, Timo, Sorsa, Lauri, Jouhi, Harri K, Mustonen, Hesham, Mohamed, Reija, Randén-Brady, Antti, Mäkitie, Timo, Atula, Jaana, Hagström, Caj, Haglund
Publikováno v:
Anticancer research. 42(11)
The oral bacteria involved in the development of periodontitis alter the tissue conditions and modify immune responses in a way that may also influence tumor development. We investigated the prevalence of R gingipain (Rgp), a key virulence factor of
Autor:
Lauri Jouhi, Timo Sorsa, Jaana Hagström, Reija Randén-Brady, Caj Haglund, Timo Atula, Hesham Mohamed, Anna Kaisa Kylmä, Antti Mäkitie
Objectives: In oropharyngeal squamous cell carcinoma (OPSCC), toll-like receptors (TLR) 5 and 7 associate with the tumor's human papilloma virus (HPV) status (Jouhi et al., 2017). TLR 2, on the other hand, has been linked to head and neck squamous ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46477ea0ff09ec32512f91a83bdc409e
http://hdl.handle.net/10138/329757
http://hdl.handle.net/10138/329757
Autor:
Jaana Hagström, Lauri Jouhi, Antti Mäkitie, Petri S. Mattila, Caj Haglund, Timo Carpén, Stina Syrjänen, Reija Randén-Brady
Publikováno v:
Cancer Immunology, Immunotherapy
Background The etiological role of human papillomavirus (HPV) in oropharyngeal squamous cell carcinoma (OPSCC) is confirmed. However, the role of other oncoviruses in OPSCC is unknown. Materials and methods A total of 158 consecutive OPSCC patients t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac1acf81bc1da7c2c076fa7da2f6b2f3
http://hdl.handle.net/10138/318893
http://hdl.handle.net/10138/318893
Autor:
Timo Carpén, Antti Mäkitie, Caj Haglund, Suvi Silén, Jaana Hagström, Reija Randén-Brady, Satu Maria Remes, Lauri Jouhi, Petri S. Mattila, Jussi Tarkkanen, Stina Syrjänen
Publikováno v:
Human pathology. 90
Current human papillomavirus (HPV) detection methods in oropharyngeal squamous cell carcinoma (OPSCC) have varying sensitivity and specificity. We aimed to compare different HPV-detection methods against the test used in clinical practice, ie, p16 im