Zobrazeno 1 - 5
of 5
pro vyhledávání: '"REI-TSANG SHIAO"'
Publikováno v:
Blood. 87:314-323
Interleukin-6 (IL-6)/IL-6 receptor (IL-6R) plays a major role in autocrine/paracrine growth regulation of myeloma cells. We investigated the effect of dexamethasone and all-trans retinoic acid, previously shown to modulate IL-6/IL-6R, on the in vitro
Publikováno v:
Leukemia & Lymphoma. 21:293-303
The cytokine IL-6 has been proposed as an autocrine growth factor in multiple myeloma, and is also required for stimulation of immunoglobulin production and secretion in normal plasma cells and myeloma cells. In this study, we showed that secreted IL
Publikováno v:
Leukemialymphoma. 17(5-6)
Uncontrolled growth of neoplastic cells and unregulated production of immunoglobulin are major components of the morbidity and mortality of multiple myeloma. Suramin, a polysulfonated napthylurea, has antitumor activity in a number of malignancies, b
Publikováno v:
The American journal of physiology. 259(6 Pt 1)
Chronic hypoxia causes polyamine-dependent hypertensive pulmonary vascular remodeling (J. E. Atkinson. J. W. Olson, R. J. Altierre, and M. N. Gillespie, J. Appl. Physiol. 62: 1562–1568, 1987), but mechanisms by which lung polyamine contents are ele
Autor:
Urszula Orlinska, Rei-Tsang Shiao, Cheryl A. Haven, Jack W. Olson, Patricia E. Rippetoe, Mark N. Gillespie, Bruce E. Maley
Publikováno v:
The American review of respiratory disease. 140(5)
Multiple lines of evidence suggest that the polyamines, a family of low-molecular-weight organic cations with documented regulatory note in cell growth and differentiation, are involved with hyperplastic and hypertrophic responses of lung cells under