Zobrazeno 1 - 10
of 17 164
pro vyhledávání: '"RECOMBINANT PROTEIN"'
Publikováno v:
Microbial Cell Factories, Vol 23, Iss 1, Pp 1-22 (2024)
Abstract Background Engineering bacteria with the purpose of optimizing the production of interesting molecules often leads to a decrease in growth due to metabolic burden or toxicity. By delaying the production in time, these negative effects on the
Externí odkaz:
https://doaj.org/article/bac85fa2d2de450cbbed44deed2a5c51
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract At present, biopharmaceuticals have received extensive attention from the society, among which recombinant proteins have a good growth trend and a large market share. Chinese hamster ovary (CHO) cells are the preferred mammalian system to pr
Externí odkaz:
https://doaj.org/article/c72c68b4d12a415083d7243c8a7ce8be
Publikováno v:
Current Issues in Molecular Biology, Vol 46, Iss 8, Pp 8958-8968 (2024)
The L-gulonolactone oxidase enzyme (GULO) catalyzes the last step of L-ascorbic acid (vitamin C) biosynthesis. This enzymatic activity is lost in primates. The full-length rat GULO has been previously produced in plants and demonstrated to be active.
Externí odkaz:
https://doaj.org/article/c7b3924a09014b4c93ec2935148257c2
Publikováno v:
Shipin Kexue, Vol 45, Iss 13, Pp 89-95 (2024)
To explore substitutes for natural tropomyosin as basic materials for the diagnosis and treatment of shrimp allergy, total RNA was extracted from Macrobrachium nipponense, and the full-length sequence of the tropomyosin gene was cloned by rapid ampli
Externí odkaz:
https://doaj.org/article/0b99905bc9a14a99b289bd97986cb001
Autor:
Matthew Smith, José Sánchez Hernández, Simon Messing, Nitya Ramakrishnan, Brianna Higgins, Jennifer Mehalko, Shelley Perkins, Vanessa E. Wall, Carissa Grose, Peter H. Frank, Julia Cregger, Phuong Vi Le, Adam Johnson, Mukul Sherekar, Morgan Pagonis, Matt Drew, Min Hong, Stephanie R. T. Widmeyer, John-Paul Denson, Kelly Snead, Ivy Poon, Timothy Waybright, Allison Champagne, Dominic Esposito, Jane Jones, Troy Taylor, William Gillette
Publikováno v:
Microbial Cell Factories, Vol 23, Iss 1, Pp 1-17 (2024)
Abstract The diversity of chemical and structural attributes of proteins makes it inherently difficult to produce a wide range of proteins in a single recombinant protein production system. The nature of the target proteins themselves, along with cos
Externí odkaz:
https://doaj.org/article/d73bb5aac7c74a0792d3cbf25a30ef55
Autor:
Lu Liu, Peng Cai, Weifang Gu, Xingxun Duan, Shiwen Gao, Xuelian Ma, Yuhui Ma, Siyuan Ma, Guoqing Li, Xiangyu Wang, Kuojun Cai, Yanfeng Wang, Tao Cai, Hongqiong Zhao
Publikováno v:
BMC Microbiology, Vol 24, Iss 1, Pp 1-14 (2024)
Abstract Rhodococcus equi (R. equi) is a zoonotic opportunistic pathogen that mainly causes fatal lung and extrapulmonary abscesses in foals and immunocompromised individuals. To date, no commercial vaccine against R. equi exists. We previously scree
Externí odkaz:
https://doaj.org/article/0f06b5e8b1d2403493feb76104731704
Autor:
Rong Tang, Ying Zeng, Yu Zhou, Qi Liang, Wei Kang, Zhonghua Yang, Xiaoxiang Zheng, Xia Zang, Hongxing Pan, Jing Jin, Fengcai Zhu
Publikováno v:
Expert Review of Vaccines, Vol 23, Iss 1, Pp 498-509 (2024)
ABSTRACTBackground Vaccination remains the cornerstone of defense against COVID-19 globally. This study aims to assess the safety and immunogenicity profile of innovative vaccines LYB001.Research design and methods This was a randomized, double-blind
Externí odkaz:
https://doaj.org/article/37e9274838794de8853f72ec7ac8733e
Autor:
Fateme Hasheminejad, Amir Amiri-Yekta
Publikováno v:
West Kazakhstan Medical Journal, Vol 66, Iss 2, Pp 137-145 (2024)
Abstract The rapid growth of the global biopharmaceutical market in recent years indicates its importance in the biotechnology industry. The production of these medicinal products is one of the fastest-growing industries in the patient treatment fiel
Externí odkaz:
https://doaj.org/article/1dc128163b6b46fcb5c667385ff19a09
Autor:
Mihail Besleaga, Christian Zimmermann, Katharina Ebner, Robert L. Mach, Astrid R. Mach-Aigner, Martina Geier, Anton Glieder, Oliver Spadiut, Julian Kopp
Publikováno v:
Microbial Cell Factories, Vol 23, Iss 1, Pp 1-14 (2024)
Abstract Background Heme-incorporating peroxygenases are responsible for electron transport in a multitude of organisms. Yet their application in biocatalysis is hindered due to their challenging recombinant production. Previous studies suggest Komag
Externí odkaz:
https://doaj.org/article/59820955ea6f4b18a7aabf9052b1dd80