Zobrazeno 1 - 10
of 724
pro vyhledávání: '"RE Champlin"'
Autor:
E Gluckman, AD Auerbach, MM Horowitz, KA Sobocinski, RC Ash, MM Bortin, A Butturini, BM Camitta, RE Champlin, W Friedrich
Publikováno v:
Blood. 86:2856-2862
Fanconi anemia is a genetic disorder associated with diverse congenital abnormalities, progressive bone marrow failure, and increased risk of leukemia and other cancers. Affected persons often die before 30 years of age. Bone marrow transplantation i
Autor:
MM Horowitz, D Przepiorka, RE Champlin, RP Gale, A Gratwohl, RH Herzig, HG Prentice, AA Rimm, O Ringden, MM Bortin
Publikováno v:
Blood. 79:2771-2774
There is substantial evidence that the volume of medical procedures in a hospital has an inverse relationship with mortality. We analyzed data for 1313 recipients of HLA-identical sibling bone marrow transplants for early leukemia (acute leukemia in
Autor:
E Gluckman, MM Horowitz, RE Champlin, JM Hows, A Bacigalupo, JC Biggs, BM Camitta, RP Gale, EC Gordon-Smith, AM Marmont
Publikováno v:
Blood. 79(1)
Data for 595 patients with severe aplastic anemia receiving HLA- identical sibling bone marrow transplants were analyzed to determine the effect of pretransplant conditioning and graft-versus-host disease (GVHD) prophylaxis on outcome. Transplants we
Autor:
AM Marmont, MM Horowitz, RP Gale, K Sobocinski, RC Ash, DW van Bekkum, RE Champlin, KA Dicke, JM Goldman, RA Good
Publikováno v:
Blood. 78(8)
We analyzed the effects of T-cell depletion on the outcome of HLA- identical sibling bone marrow transplants for leukemia by comparing 731 T-cell-depleted transplants with 2,480 non-T-cell-depleted transplants. T-cell depletion decreased acute graft-
Publikováno v:
Blood. 77(7)
We combined the polymerase chain reaction (PCR) with oligonucleotide hybridization as a novel and sensitive technique to evaluate posttransplant chimerism. Specific oligonucleotides for hybridization were synthesized homologous to tandemly repetitive
Publikováno v:
Blood. 66(1)
We analyzed the effect of antithymocyte globulin (ATG) with or without androgens in 121 patients with aplastic anemia. Fifty-three patients with moderate to severe aplastic anemia were prospectively randomized to receive ATG with or without oral andr
Autor:
RE Champlin, MM Horowitz, DW van Bekkum, BM Camitta, GE Elfenbein, RP Gale, E Gluckman, RA Good, AA Rimm, C Rozman
Publikováno v:
Blood. 73(2)
Graft failure was analyzed in 625 patients receiving allogeneic bone marrow transplants from HLA-identical sibling donors as treatment for severe aplastic anemia. Sixty-eight (11%) had no or only transient engraftment. Second bone marrow transplants
Publikováno v:
Blood. 73(3)
Fifteen patients with refractory aplastic anemia or agranulocytosis received treatment with recombinant human granulocyte-macrophage-colony- stimulating factor (rhGM-CSF) in doses from 4 to 64 micrograms/kg/d by continuous intravenous (IV) infusion.
Publikováno v:
Blood. 65(4)
Twenty-two patients with hairy cell leukemia were treated with biosynthetic (recombinant) alpha-2-interferon in an open-label, single- arm efficacy study. Patients received 2 X 10(6) U/m2 recombinant alpha- 2-interferon three times weekly. Therapy wa