A prognostic model predicted deterioration in health-related quality of life in older patients with multimorbidity and polypharmacy

Autor: Paul Glasziou, Henrik Rudolf, Donna Bosch-Lenders, Walter E. Haefeli, Daniela Küllenberg de Gaudry, Ulrich Thiem, Ghainsom Kom, Ferdinand M. Gerlach, Hans J. Trampisch, Joerg J Meerpohl, Jeanet W. Blom, Petra J. M. Elders, Benno Flaig, Rafael Perera, Truc Sophia Dinh, Andreas D. Meid, Karin M A Swart, Kym I E Snell, Ana Isabel González-González, Christiane Muth, Marjan van den Akker

Publikováno v: González-González, A I, Meid, A D, Dinh, T S, Blom, J W, van den Akker, M, Elders, P J M, Thiem, U, De Gaudry, D K, Swart, K M A, Rudolf, H, Bosch-Lenders, D, Trampisch, H J, Meerpohl, J J, Gerlach, F M, Flaig, B, Kom, G, Snell, K I E, Perera, R, Haefeli, W E, Glasziou, P P & Muth, C 2021, ' A prognostic model predicted deterioration in health-related quality of life in older patients with multimorbidity and polypharmacy ', Journal of Clinical Epidemiology, vol. 130, pp. 1-12 . https://doi.org/10.1016/j.jclinepi.2020.10.006
Journal of Clinical Epidemiology
Journal of Clinical Epidemiology, 130, 1-12. Elsevier USA
Journal of Clinical Epidemiology, 130, 1-12. Elsevier Science
Journal of Clinical Epidemiology, 130, 1-12. ELSEVIER SCIENCE INC

Objectives: To develop and validate a prognostic model to predict deterioration in health-related quality of life (dHRQoL) in older general practice patients with at least one chronic condition and one chronic prescription. Study Design and Setting:

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::680ceb2f6964eef1272ef41a0bc31253
https://doi.org/10.1016/j.jclinepi.2020.10.006

Intermittent hypoxia treatment alleviates memory impairment in the 6-month-old APPswe/PS1dE9 mice and reduces amyloid beta accumulation and inflammation in the brain

Autor: Lingling Zhu, Xiangpei Yue, Tong Zhao, Ruoli Chen, Xin Huang, Meng Qiao, Yong-Qi Zhao, Yanzhao Zhou, Ming Fan, Xiang Cheng, Xingnan Zhao

Publikováno v: Alzheimer's Research & Therapy
Alzheimer’s Research & Therapy, Vol 13, Iss 1, Pp 1-16 (2021)

Background Alzheimer’s disease (AD) is a progressive, degenerative, and terminal disease without cure. There is an urgent need for a new strategy to treat AD. The aim of this study was to investigate the effects of intermittent hypoxic treatment (I

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b66e30f3e654a6287607fcc52ca2197a
https://pubmed.ncbi.nlm.nih.gov/34844651

Haemoglobin and transfusions in elderly patients with hip fractures: the effect of a dedicated orthogeriatrician

Autor: Marco Quaranta, Gabriela Pezzuti, Francesco Oliva, Nicola Maffulli, Filippo Migliorini, Luca Miranda

Publikováno v: Journal of Orthopaedic Surgery and Research
Journal of Orthopaedic Surgery and Research, Vol 16, Iss 1, Pp 1-8 (2021)

Background Hip fractures are common in elderly patients, in whom it is important to monitor blood loss; however, unnecessary transfusions should be avoided. The primary objective of this study was to assess whether the employment of a dedicated ortho

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d8c53e0b7d9b919da45c36684b2e592
http://hdl.handle.net/11386/4805137

Co-designing an Adaption of a Mobile App to Enhance Communication, Safety, and Well-being Among People Living at Home With Early-Stage Dementia: Protocol for an Exploratory Multiple Case Study

Autor: Karen Davies, Sudeh Cheraghi-Sohi, Bie Nio Ong, Katherine Perryman, Caroline Sanders

Publikováno v: JMIR Research Protocols

Background There is a growing interest in using mobile apps to support communication, safety, and well-being. Evidence directly from people with dementia regarding the usability, usefulness, and relevance of mobile apps is limited. Objective This pap

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::adf36dfe49df48e7363e609d6568d6aa
https://pubmed.ncbi.nlm.nih.gov/34932011

Community Ageing Research 75+ (CARE75+) REMOTE study: a remote model of recruitment and assessment of the health, well-being and social circumstances of older people

Autor: Elizabeth Teale, Kate E. Best, Sarah Hallas, Caroline Brundle, Tracey Young, Karen Spilsbury, Farhat Mahmood, Barbara Hanratty, Andrew Clegg, Rebecca Hawkins, Ikhlaq Jacob, Victoria A Goodwin, Carolyn Chew-Graham, Lesley Brown, Catherine Quinn, Amrit Daffu-O’Reilly, Anne Heaven

Publikováno v: BMJ Open, Vol 11, Iss 11 (2021)
BMJ Open

IntroductionThe Community Ageing Research 75+ (CARE75+) study is a longitudinal cohort study collecting extensive health and social data, with a focus on frailty, independence and quality of life in older age. CARE75+ was the first international expe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78e7f228f074d1da9a48957d7e24b3eb
https://doi.org/10.1136/bmjopen-2020-048524