RANTES- and interleukin-8-induced responses in normal human eosinophils: effects of priming with interleukin-5

Autor: RC Schweizer, BA Welmers, JA Raaijmakers, P Zanen, JW Lammers, L Koenderman

Publikováno v: Blood. 83(12)

We report that responses of normal human eosinophils toward the chemokines RANTES and interleukin-8 (IL-8) are modulated and upregulated by priming with IL-5. In a modified Boyden chamber assay, we studied migratory responses toward the members of th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::903a2851a88f97af0505533a15495046
https://pubmed.ncbi.nlm.nih.gov/7515718

Diagnosing eosinophilic asthma using a multivariate prediction model based on blood granulocyte responsiveness.

Autor: Hilvering B; Department of Respiratory Medicine, Laboratory of Translational Immunology, University Medical Centre Utrecht, Utrecht, The Netherlands.; Nuffield Department of Medicine, Oxford University, Oxford, UK., Vijverberg SJH; Department of Respiratory Medicine, Laboratory of Translational Immunology, University Medical Centre Utrecht, Utrecht, The Netherlands.; Division of Pharmacoepidemiology & Clinical Pharmacology, Utrecht Institute for Pharmaceutical Sciences (UIPS), Faculty of Science, Utrecht University, Utrecht, The Netherlands., Jansen J; Institute for Molecules and Materials, Radboud Universiteit Nijmegen, Nijmegen, The Netherlands., Houben L; Department of Respiratory Medicine, Laboratory of Translational Immunology, University Medical Centre Utrecht, Utrecht, The Netherlands., Schweizer RC; Department of Respiratory Medicine, Laboratory of Translational Immunology, University Medical Centre Utrecht, Utrecht, The Netherlands., Go S; Nuffield Department of Medicine, Oxford University, Oxford, UK., Xue L; Nuffield Department of Medicine, Oxford University, Oxford, UK., Pavord ID; Nuffield Department of Medicine, Oxford University, Oxford, UK., Lammers JJ; Department of Respiratory Medicine, Laboratory of Translational Immunology, University Medical Centre Utrecht, Utrecht, The Netherlands., Koenderman L; Department of Respiratory Medicine, Laboratory of Translational Immunology, University Medical Centre Utrecht, Utrecht, The Netherlands.

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Steroids induce a disequilibrium of secreted interleukin-1 receptor antagonist and interleukin-1β synthesis by human neutrophils.

Autor: Langereis JD; Dept of Respiratory Medicine, University Medical Center Utrecht, Utrecht, The Netherlands. l.ulfman@umcutrecht.nl, Oudijk EJ, Schweizer RC, Lammers JW, Koenderman L, Ulfman LH

Publikováno v: The European respiratory journal [Eur Respir J] 2011 Feb; Vol. 37 (2), pp. 406-15. Date of Electronic Publication: 2010 Jul 22.

Effects of glucocorticoids on the neutrophil count: a cohort study among hospitalized patients.

Autor: Velthove KJ; Faculty of Science, Division of Pharmacoepidemiology and Pharmacotherapy, Utrecht Institute of Pharmaceutical Sciences, Utrecht University, P.O. Box 80082, 3508 TB Utrecht, The Netherlands., Leufkens HG, Souverein PC, Schweizer RC, Bracke M, van Solinge WW

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Identification of exacerbations in obstructive lung disease through biomarkers.

Autor: Velthove KJ; Faculty of Science, Division of Pharmacoepidemiology and Pharmacotherapy, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, The Netherlands., Bracke M, Souverein PC, Schweizer RC, Ten Berg MJ, Leufkens HG, van Solinge WW

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