Enhanced methionine cycle suppresses naïve CD8+ T-cell maturation

Autor: A Saragovi, X Zheng, I Abramovich, L Cohen-Daniel, L Zhuoning, H Raifer, I Omar, A Swisa, M Kuchersky, A Drori, F Marini, O Toker, R Somech, Ch Schmidl, RC Hendrickson, E Gottlieb, M Huber, M Berger

The metabolic pathways controlling naive CD8+ T (Tn) cell maturation following thymic egress remain mostly undefined. This is important because immature Tn are a major component of peripheral immune tolerance in newborns and under lymphopenia. In thi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::efd02e04cf93a9d7a922b449e61d4acd
https://doi.org/10.1101/2022.08.16.504136

Changes to virus taxonomy and the ICTV Statutes ratified by the International Committee on Taxonomy of Viruses (2024).

Autor: Simmonds P; Nuffield Department of Medicine, University of Oxford, Peter Medawar Building, South Parks Road, Oxford, OX1 3SY, UK. Peter.Simmonds@ndm.ox.ac.uk., Adriaenssens EM; Quadram Institute Bioscience, Norwich Research Park, Norwich, NR4 7UQ, UK., Lefkowitz EJ; Department of Microbiology, University of Alabama at Birmingham, BBRB 276, 845 19th St South, Birmingham, AL, 35294-2170, USA., Oksanen HM; Molecular and Integrative Biosciences Research Programme, Faculty of Biological and Environmental Sciences, University of Helsinki, Viikinkaari 9, 00014, Helsinki, Finland., Siddell SG; School of Cellular and Molecular Medicine, Faculty of Life Sciences, University of Bristol, University Walk, Bristol, BS8 1TD, UK., Zerbini FM; Departamento de Fitopatologia/BIOAGRO, Universidade Federal de Viçosa, Viçosa, MG, 36570-900, Brazil., Alfenas-Zerbini P; Departamento de Microbiologia, Universidade Federal de Viçosa, Viçosa, MG, 36570-900, Brazil., Aylward FO; Department of Biological Sciences, Virginia Tech, Blacksburg, VA, USA., Dempsey DM; Department of Microbiology, University of Alabama at Birmingham, BBRB 276, 845 19th St South, Birmingham, AL, 35294-2170, USA., Dutilh BE; Institute of Biodiversity, Faculty of Biological Sciences, Cluster of Excellence Balance of the Microverse, Friedrich Schiller University, Fürstengraben 1, 07743, Jena, Germany.; Theoretical Biology and Bioinformatics, Department of Biology, Utrecht University, Padualaan 8, 3584 CH, Utrecht, The Netherlands., Freitas-Astúa J; Embrapa Cassava and Fruits, Brazilian Agricultural Research Corporation, Cruz das Almas, BA, 44380-000, Brazil., García ML; Instituto de Biotecnología y Biología Molecular, CCT-La Plata, CONICET-UNLP, Calles 47 y 115 (1900), La Plata, Buenos Aires, Argentina., Hendrickson RC; Department of Microbiology, University of Alabama at Birmingham, BBRB 276, 845 19th St South, Birmingham, AL, 35294-2170, USA., Hughes HR; Centers for Disease Control and Prevention, Fort Collins, Colorado, USA., Junglen S; Institute of Virology, Charité-Universitätsmedizin, Corporate Member of Free University Berlin, Humboldt-University Berlin, and Berlin Institute of Health, Berlin, Germany., Krupovic M; Archaeal Virology Unit, Institut Pasteur, Université Paris Cité, CNRS UMR6047, 25 rue du Dr Roux, 75015, Paris, France., Kuhn JH; Integrated Research Facility at Fort Detrick, Division of Clinical Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, B-8200 Research Plaza, Fort Detrick, Frederick, MD, 21702, USA., Lambert AJ; Division of Vector-Borne Diseases, Centers for Disease Control and Prevention, National Center for Emerging and Zoonotic Infectious Diseases, Fort Collins, CO, 80521, USA., Łobocka M; Institute of Biochemistry and Biophysics of the Polish Academy of Sciences, 02-106, Warsaw, Poland., Mushegian AR; Division of Molecular and Cellular Biosciences, National Science Foundation, 2415 Eisenhower Avenue, Alexandria, VA, 22314, USA., Penzes J; Institute for Quantitative Biomedicine, Rutgers University, Piscataway, New Jersey, USA., Muñoz AR; Departamento de Ciencias Biológicas, Universidad de los Andes, Bogotá, Colombia., Robertson DL; MRC-University of Glasgow Centre for Virus Research, Sir Michael Stoker Building, 464 Bearsden Road, Glasgow, G61 1QH, UK., Roux S; DOE Joint Genome Institute, Lawrence Berkeley National Laboratory, Berkeley, California, USA., Rubino L; Consiglio Nazionale delle Ricerche, Istituto per la Protezione Sostenibile delle Piante, Sede Secondaria di Bari, Via Amendola 165/A, 70126, Bari, Italy., Sabanadzovic S; Department of Agricultural Science and Plant Protection, Mississippi State University, Mississippi State, MS, 39762, USA.; Institute for Genomics, Biocomputing and Biotechnology, Mississippi State University, Mississippi State, MS, 39762, USA., Smith DB; Nuffield Department of Medicine, University of Oxford, Peter Medawar Building, South Parks Road, Oxford, OX1 3SY, UK., Suzuki N; Institute of Plant Science and Resources, Okayama University, Kurashiki, Okayama, 710-0046, Japan., Turner D; School of Applied Sciences, Faculty of Health, Science and Society, University of the West of England, Bristol, UK., Van Doorslaer K; Department of Immunobiology, School of Animal and Comparative Biomedical Sciences, BIO5 Institute, University of Arizona Cancer Center, Tucson, AZ, 85721, USA., Vandamme AM; Department of Microbiology, Immunology and Transplantation, Clinical and Epidemiological Virology, Rega Institute for Medical Research, KU Leuven, 3000, Leuven, Belgium.; Center for Global Health and Tropical Medicine, Instituto de Higiene e Medicina Tropical, Universidade Nova de Lisboa, Rua da Junqueira, 100, 1349-008, Lisbon, Portugal., Varsani A; The Biodesign Center for Fundamental and Applied Microbiomics, School of Life Sciences, Center for Evolution and Medicine, Arizona State University, Tempe, AZ, 85287-4701, USA.

Publikováno v: Archives of virology [Arch Virol] 2024 Nov 03; Vol. 169 (11), pp. 236. Date of Electronic Publication: 2024 Nov 03.

Proteomic basis for pancreatic acinar cell carcinoma and pancreatoblastoma as similar yet distinct entities.

Autor: Tanaka A; Department of Pathology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.; Department of Pathology and Laboratory Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Ogawa M; Department of Pathology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.; Department of Pathology and Laboratory Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Zhou Y; Department of Pathology and Laboratory Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; ICU Department, Second Affiliated Hospital of Nanchang University, Nanchang, Jiangxi, China., Hendrickson RC; Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Miele MM; Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Li Z; Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Klimstra DS; Department of Pathology and Laboratory Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Paige.AI, New York, NY, USA., Wang JY; Curandis Biomedical, Chestnut Hill, MA, USA. julia@curandis.com., Roehrl MHA; Department of Pathology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA. michael_roehrl@bidmc.harvard.edu.; Department of Pathology and Laboratory Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA. michael_roehrl@bidmc.harvard.edu.

Publikováno v: NPJ precision oncology [NPJ Precis Oncol] 2024 Oct 03; Vol. 8 (1), pp. 221. Date of Electronic Publication: 2024 Oct 03.

β2 integrins impose a mechanical checkpoint on macrophage phagocytosis.

Autor: Settle AH; Louis V. Gerstner, Jr., Graduate School of Biomedical Sciences, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Immunology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Winer BY; Immunology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA., de Jesus MM; Louis V. Gerstner, Jr., Graduate School of Biomedical Sciences, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Immunology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Seeman L; Immunology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Wang Z; Immunology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Immunology & Molecular Pathogenesis Program, Weill Cornell Graduate School of Medical Sciences, New York, NY, USA., Chan E; Molecular Cytology Core Facility, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Romin Y; Molecular Cytology Core Facility, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Li Z; Proteomics Core Facility, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Miele MM; Proteomics Core Facility, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Hendrickson RC; Proteomics Core Facility, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Molecular Pharmacology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Department of Biochemistry and Molecular Biology, University of Miami School of Medicine, Miami, FL, USA., Vorselen D; Cell Biology and Immunology, Wageningen University & Research, Wageningen, The Netherlands., Perry JSA; Louis V. Gerstner, Jr., Graduate School of Biomedical Sciences, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Immunology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Immunology & Molecular Pathogenesis Program, Weill Cornell Graduate School of Medical Sciences, New York, NY, USA., Huse M; Louis V. Gerstner, Jr., Graduate School of Biomedical Sciences, Memorial Sloan Kettering Cancer Center, New York, NY, USA. husem@mskcc.org.; Immunology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA. husem@mskcc.org.; Immunology & Molecular Pathogenesis Program, Weill Cornell Graduate School of Medical Sciences, New York, NY, USA. husem@mskcc.org.

Publikováno v: Nature communications [Nat Commun] 2024 Sep 18; Vol. 15 (1), pp. 8182. Date of Electronic Publication: 2024 Sep 18.

Protocol for the quantitative identification of endogenously ISGylated proteins from mammalian cell lines.

Autor: Wardlaw CP; Molecular Biology Program, Memorial Sloan-Kettering Cancer Center, New York, NY 10065, USA. Electronic address: wardlawc@mskcc.org., Miele MM; Proteomics Core Facility, Memorial Sloan-Kettering Cancer Center, New York, NY 10065, USA., Li Z; Proteomics Core Facility, Memorial Sloan-Kettering Cancer Center, New York, NY 10065, USA., Hendrickson RC; Proteomics Core Facility, Memorial Sloan-Kettering Cancer Center, New York, NY 10065, USA., Petrini JHJ; Molecular Biology Program, Memorial Sloan-Kettering Cancer Center, New York, NY 10065, USA. Electronic address: petrinij@mskcc.org.

Publikováno v: STAR protocols [STAR Protoc] 2024 Mar 15; Vol. 5 (1), pp. 102843. Date of Electronic Publication: 2024 Jan 29.