Cryoablation Without Excision for Early-Stage Breast Cancer: ICE3 Trial 5-Year Follow-Up on Ipsilateral Breast Tumor Recurrence.

Autor: Fine RE; Margaret West Comprehensive Breast Center, West Cancer Center and Research Institute, Germantown, TN, USA. rfine@westclinic.com., Gilmore RC; Margaret West Comprehensive Breast Center, West Cancer Center and Research Institute, Germantown, TN, USA., Tomkovich KR; CentraState Medical Center, Freehold, NJ, USA., Dietz JR; University Hospital Cleveland Medical Center, Cleveland, OH, USA.; Cleveland, OH, USA., Berry MP; Margaret West Comprehensive Breast Center, West Cancer Center and Research Institute, Germantown, TN, USA., Hernandez LE; Cincinnati Breast Surgeons Inc, Cincinnati, OH, USA., Columbus KS; Cincinnati Breast Surgeons Inc, Cincinnati, OH, USA., Seedman SA; Presbyterian Cancer Center, Rio Rancho, NM, USA., Fisher CS; Indiana University IU Health Hospital-University Hospital, Indianapolis, IN, USA., Han LK; Indiana University IU Health Hospital-University Hospital, Indianapolis, IN, USA., Manahan ER; Dalton Surgical Group, Dalton, GA, USA., Hicks RD; Regional Medical Imaging, Flint, MI, USA., Vaidya RP; Ironwood Cancer and Research Centers, Glendale, AZ, USA., Curcio LD; BreastLink Laguna Hills, Laguna Hills, CA, USA., Sevrukov AB; Thomas Jefferson University Hospital, Philadelphia, PA, USA., Kenler AS; Bridgeport Hospital, Bridgeport, CT, USA., Taback B; Columbia University Medical Center, New York, NY, USA., Chen M; Columbia University Medical Center, New York, NY, USA., Miller ME; University Hospital Cleveland Medical Center, Cleveland, OH, USA., Gold L; Comprehensive Breast Care, Troy, MI, USA., Anglin BV; Complete Breast Care, Plano, TX, USA., Aoun HD; Karmanos Cancer Institute, Detroit, MI, USA., Simmons RM; Weill Cornell Weill Medical College, Cornell University, New York, NY, USA., Feldman SM; Montefiore-Einstein Center for Cancer Care, New York, NY, USA., Boolbol SK; Mount Sinai Beth Israel, New York, NY, USA.; Nuvance Health System, Poughkeepsie, NY, USA.

Publikováno v: Annals of surgical oncology [Ann Surg Oncol] 2024 Oct; Vol. 31 (11), pp. 7273-7283. Date of Electronic Publication: 2024 Sep 16.

Proximal and Distal Bronchioles Contribute to the Pathogenesis of Non-Cystic Fibrosis Bronchiectasis.

Autor: Asakura T; Marsico Lung Institute/Cystic Fibrosis Research Center.; Department of Clinical Medicine, Laboratory of Bioregulatory Medicine, Kitasato University School of Pharmacy, Tokyo, Japan.; Department of Respiratory Medicine, Kitasato University, Kitasato Institute Hospital, Tokyo, Japan.; Division of Pulmonary Medicine, Department of Medicine., Okuda K; Marsico Lung Institute/Cystic Fibrosis Research Center., Chen G; Marsico Lung Institute/Cystic Fibrosis Research Center., Dang H; Marsico Lung Institute/Cystic Fibrosis Research Center., Kato T; Marsico Lung Institute/Cystic Fibrosis Research Center., Mikami Y; Marsico Lung Institute/Cystic Fibrosis Research Center., Schworer SA; Marsico Lung Institute/Cystic Fibrosis Research Center., Gilmore RC; Marsico Lung Institute/Cystic Fibrosis Research Center., Radicioni G; Marsico Lung Institute/Cystic Fibrosis Research Center., Hawkins P; Marsico Lung Institute/Cystic Fibrosis Research Center., Barbosa Cardenas SM; Marsico Lung Institute/Cystic Fibrosis Research Center., Saito M; Marsico Lung Institute/Cystic Fibrosis Research Center., Cawley AM; Marsico Lung Institute/Cystic Fibrosis Research Center., De la Cruz G; Pathology Services Core, Lineberger Comprehensive Cancer Center, and., Chua M; Marsico Lung Institute/Cystic Fibrosis Research Center., Alexis NE; Center for Environmental Medicine, Asthma, and Lung Biology, Division of Allergy and Immunology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina., Masugi Y; Department of Pathology, and., Noone PG; Marsico Lung Institute/Cystic Fibrosis Research Center., Ribeiro CMP; Marsico Lung Institute/Cystic Fibrosis Research Center., Kesimer M; Marsico Lung Institute/Cystic Fibrosis Research Center., Olivier KN; Marsico Lung Institute/Cystic Fibrosis Research Center.; Pulmonary Branch, National Heart, Lung, and Blood Institute, NIH, Bethesda, Maryland., Hasegawa N; Department of Infectious Diseases, Keio University School of Medicine, Tokyo, Japan; and., Randell SH; Marsico Lung Institute/Cystic Fibrosis Research Center., O'Neal WK; Marsico Lung Institute/Cystic Fibrosis Research Center., Boucher RC; Marsico Lung Institute/Cystic Fibrosis Research Center.

Publikováno v: American journal of respiratory and critical care medicine [Am J Respir Crit Care Med] 2024 Feb 15; Vol. 209 (4), pp. 374-389.

An epithelial-immune circuit amplifies inflammasome and IL-6 responses to SARS-CoV-2.

Autor: Barnett KC; Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA; Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA; Department of Microbiology and Immunology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA., Xie Y; Department of Computational Mathematics, Science and Engineering, Michigan State University, East Lansing, MI 48824, USA; Department of Statistics and Probability, Michigan State University, East Lansing, MI 48824, USA., Asakura T; Marsico Lung Institute, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA., Song D; Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA; Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA; Department of Microbiology and Immunology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA., Liang K; Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA; Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA; Department of Microbiology and Immunology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA; Oral and Craniofacial Biomedicine Program, Adams School of Dentistry, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA., Taft-Benz SA; Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA., Guo H; Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA; Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA; Department of Microbiology and Immunology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA., Yang S; Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA; Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA; Department of Microbiology and Immunology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA., Okuda K; Marsico Lung Institute, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA., Gilmore RC; Marsico Lung Institute, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA., Loome JF; Department of Microbiology and Immunology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA., Oguin Iii TH; Duke Human Vaccine Institute, Durham, NC 27701, USA., Sempowski GD; Duke Human Vaccine Institute, Durham, NC 27701, USA., Randell SH; Department of Statistics and Probability, Michigan State University, East Lansing, MI 48824, USA., Heise MT; Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA; Department of Microbiology and Immunology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA., Lei YL; Department of Periodontics and Oral Medicine, Rogel Cancer Center, University of Michigan, Ann Arbor, MI 48104, USA; Department of Otolaryngology-Head and Neck Surgery, Rogel Cancer Center, University of Michigan, Ann Arbor, MI 48109, USA., Boucher RC; Marsico Lung Institute, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA., Ting JP; Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA; Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA; Department of Microbiology and Immunology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA. Electronic address: jenny_ting@med.unc.edu.

Publikováno v: Cell host & microbe [Cell Host Microbe] 2023 Feb 08; Vol. 31 (2), pp. 243-259.e6. Date of Electronic Publication: 2022 Dec 09.

Prevalence and Mechanisms of Mucus Accumulation in COVID-19 Lung Disease.

Autor: Kato T; Marsico Lung Institute., Asakura T; Marsico Lung Institute., Edwards CE; Department of Epidemiology., Dang H; Marsico Lung Institute., Mikami Y; Marsico Lung Institute., Okuda K; Marsico Lung Institute., Chen G; Marsico Lung Institute., Sun L; Marsico Lung Institute., Gilmore RC; Marsico Lung Institute., Hawkins P; Marsico Lung Institute., De la Cruz G; Pathology Services Core, Lineberger Comprehensive Cancer Center, and., Cooley MR; Department of Epidemiology., Bailey AB; Department of Epidemiology., Hewitt SM; Laboratory of Pathology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland., Chertow DS; Critical Care Medicine Department, National Institutes of Health Clinical Center, Bethesda, Maryland; and., Borczuk AC; Department of Pathology and Laboratory Medicine and., Salvatore S; Department of Pathology and Laboratory Medicine and., Martinez FJ; Pulmonary Critical Care Medicine, Weill Cornell Medicine, New York, New York., Thorne LB; Department of Pathology and Laboratory Medicine, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina., Askin FB; Department of Pathology and Laboratory Medicine, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina., Ehre C; Marsico Lung Institute., Randell SH; Marsico Lung Institute., O'Neal WK; Marsico Lung Institute., Baric RS; Department of Epidemiology., Boucher RC; Marsico Lung Institute.

Publikováno v: American journal of respiratory and critical care medicine [Am J Respir Crit Care Med] 2022 Dec 01; Vol. 206 (11), pp. 1336-1352.

Genome-wide bidirectional CRISPR screens identify mucins as host factors modulating SARS-CoV-2 infection.

Autor: Biering SB; Division of Infectious Diseases and Vaccinology, School of Public Health, University of California, Berkeley, Berkeley, CA, USA., Sarnik SA; Department of Bioengineering, University of California, Berkeley, Berkeley, CA, USA.; Innovative Genomics Institute, University of California, Berkeley, Berkeley, CA, USA., Wang E; Department of Bioengineering, University of California, Berkeley, Berkeley, CA, USA.; Innovative Genomics Institute, University of California, Berkeley, Berkeley, CA, USA., Zengel JR; Department of Microbiology and Immunology, Stanford University School of Medicine, Stanford, CA, USA., Leist SR; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Schäfer A; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Sathyan V; Department of Bioengineering, University of California, Berkeley, Berkeley, CA, USA.; Innovative Genomics Institute, University of California, Berkeley, Berkeley, CA, USA., Hawkins P; Marsico Lung Institute and Cystic Fibrosis Research Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Okuda K; Marsico Lung Institute and Cystic Fibrosis Research Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Tau C; Department of Bioengineering, University of California, Berkeley, Berkeley, CA, USA.; Innovative Genomics Institute, University of California, Berkeley, Berkeley, CA, USA., Jangid AR; Department of Bioengineering, University of California, Berkeley, Berkeley, CA, USA.; Innovative Genomics Institute, University of California, Berkeley, Berkeley, CA, USA., Duffy CV; Department of Biochemistry, Stanford University School of Medicine, Stanford, CA, USA., Wei J; Department of Laboratory Medicine, Yale School of Medicine, New Haven, CT, USA.; Department of Immunobiology, Yale School of Medicine, New Haven, CT, USA., Gilmore RC; Marsico Lung Institute and Cystic Fibrosis Research Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Alfajaro MM; Department of Laboratory Medicine, Yale School of Medicine, New Haven, CT, USA.; Department of Immunobiology, Yale School of Medicine, New Haven, CT, USA., Strine MS; Department of Laboratory Medicine, Yale School of Medicine, New Haven, CT, USA.; Department of Immunobiology, Yale School of Medicine, New Haven, CT, USA., Nguyenla X; Division of Infectious Diseases and Vaccinology, School of Public Health, University of California, Berkeley, Berkeley, CA, USA., Van Dis E; Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA, USA., Catamura C; Center for Computational Biology, University of California, Berkeley, Berkeley, CA, USA., Yamashiro LH; Division of Infectious Diseases and Vaccinology, School of Public Health, University of California, Berkeley, Berkeley, CA, USA.; Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA, USA., Belk JA; Department of Biochemistry, Stanford University School of Medicine, Stanford, CA, USA., Begeman A; Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA, USA., Stark JC; Department of Chemistry and Stanford ChEM-H, Stanford University, Stanford, CA, USA., Shon DJ; Department of Chemistry and Stanford ChEM-H, Stanford University, Stanford, CA, USA., Fox DM; Division of Infectious Diseases and Vaccinology, School of Public Health, University of California, Berkeley, Berkeley, CA, USA.; Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA, USA., Ezzatpour S; Department of Microbiology and Immunology, College of Veterinary Medicine, Cornell University, Ithaca, NY, USA., Huang E; Marsico Lung Institute and Cystic Fibrosis Research Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.; Department of Biochemistry and Biophysics, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Olegario N; Marsico Lung Institute and Cystic Fibrosis Research Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.; Department of Biochemistry and Biophysics, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Rustagi A; Department of Medicine, Division of Infectious Diseases and Geographic Medicine, Stanford University School of Medicine, Stanford, CA, USA., Volmer AS; Marsico Lung Institute and Cystic Fibrosis Research Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Livraghi-Butrico A; Marsico Lung Institute and Cystic Fibrosis Research Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Wehri E; The Henry Wheeler Center for Emerging and Neglected Diseases, Berkeley, CA, USA., Behringer RR; Department of Genetics, University of Texas MD Anderson Cancer Center, Houston, TX, USA., Cheon DJ; Department of Regenerative and Cancer Cell Biology, Albany Medical College, Albany, NY, USA., Schaletzky J; The Henry Wheeler Center for Emerging and Neglected Diseases, Berkeley, CA, USA., Aguilar HC; Department of Microbiology and Immunology, College of Veterinary Medicine, Cornell University, Ithaca, NY, USA., Puschnik AS; Chan Zuckerberg Biohub, San Francisco, CA, USA., Button B; Marsico Lung Institute and Cystic Fibrosis Research Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.; Department of Biochemistry and Biophysics, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Pinsky BA; Department of Medicine, Division of Infectious Diseases and Geographic Medicine, Stanford University School of Medicine, Stanford, CA, USA.; Department of Pathology, Stanford University School of Medicine, Stanford, CA, USA., Blish CA; Department of Medicine, Division of Infectious Diseases and Geographic Medicine, Stanford University School of Medicine, Stanford, CA, USA.; Chan Zuckerberg Biohub, San Francisco, CA, USA., Baric RS; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., O'Neal WK; Marsico Lung Institute and Cystic Fibrosis Research Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Bertozzi CR; Department of Chemistry and Stanford ChEM-H, Stanford University, Stanford, CA, USA.; Howard Hughes Medical Institute, Stanford University, Stanford, CA, USA., Wilen CB; Department of Laboratory Medicine, Yale School of Medicine, New Haven, CT, USA.; Department of Immunobiology, Yale School of Medicine, New Haven, CT, USA.; Yale Cancer Center, Yale School of Medicine, New Haven, CT, USA., Boucher RC; Marsico Lung Institute and Cystic Fibrosis Research Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Carette JE; Department of Microbiology and Immunology, Stanford University School of Medicine, Stanford, CA, USA., Stanley SA; Division of Infectious Diseases and Vaccinology, School of Public Health, University of California, Berkeley, Berkeley, CA, USA.; Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA, USA., Harris E; Division of Infectious Diseases and Vaccinology, School of Public Health, University of California, Berkeley, Berkeley, CA, USA. eharris@berkeley.edu., Konermann S; Department of Biochemistry, Stanford University School of Medicine, Stanford, CA, USA. silvanak@stanford.edu.; Arc Institute, Palo Alto, CA, USA. silvanak@stanford.edu., Hsu PD; Department of Bioengineering, University of California, Berkeley, Berkeley, CA, USA. pdhsu@berkeley.edu.; Innovative Genomics Institute, University of California, Berkeley, Berkeley, CA, USA. pdhsu@berkeley.edu.; Center for Computational Biology, University of California, Berkeley, Berkeley, CA, USA. pdhsu@berkeley.edu.; Arc Institute, Palo Alto, CA, USA. pdhsu@berkeley.edu.

Publikováno v: Nature genetics [Nat Genet] 2022 Aug; Vol. 54 (8), pp. 1078-1089. Date of Electronic Publication: 2022 Jul 25.