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pro vyhledávání: '"RBD, Receptor Binding Domain"'
Akademický článek
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Autor:
Max Luedemann, Daniela Stadler, Cho-Chin Cheng, Ulrike Protzer, Percy A. Knolle, Sainitin Donakonda
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 20, Iss, Pp 799-811 (2022)
Computational and Structural Biotechnology Journal
Comp. Struc. Biotech. J. 20, 799-811 (2022)
Computational and Structural Biotechnology Journal
Comp. Struc. Biotech. J. 20, 799-811 (2022)
Graphical abstract
Drug-repurposing has been instrumental to identify drugs preventing SARS-CoV-2 replication or attenuating the disease course of COVID-19. Here, we identify through structure-based drug-repurposing a dual-purpose inhibitor of S
Drug-repurposing has been instrumental to identify drugs preventing SARS-CoV-2 replication or attenuating the disease course of COVID-19. Here, we identify through structure-based drug-repurposing a dual-purpose inhibitor of S
Autor:
Kai Wu, Carole Henry, Charis Palandjian, Sarah O’Connell, Angela Woods, Darin K. Edwards, Anna Hill, Hamilton Bennett, Naveen Nunna, Elisabeth Narayanan, Samantha Falcone, Matthew A. Koch, Andrea Carfi, Robert A. Seder, Diana Lee, Guillaume Stewart-Jones, LingZhi Ma, Barney S. Graham, Angela Choi, Tonya M. Colpitts, Kizzmekia S. Corbett, Adrian B. McDermott, Sayda Elbashir, Julian Quinones, Hardik Jani
Publikováno v:
bioRxiv
Vaccine
Vaccine
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative agent of a global pandemic that has led to more than 2.8 million deaths worldwide. Safe and effective vaccines are now available, including Moderna’s COVID-19 vaccine (mR
Autor:
C. Caffau, Agostino Steffan, Maria Rita Cozzi, Elena Muraro, Chiara Corso, Mariateresa Casarotto, Marcella Montico, Federico Ronchese, Stefania Zanussi, Roberto Vettori, Chiara Evangelista, Matteo Turetta, Giulia Brisotto
Publikováno v:
Clinica Chimica Acta; International Journal of Clinical Chemistry
Background and aims Monitoring the immune response against SARS-CoV-2 is pivotal in the evaluation of long-term vaccine efficacy. Immunoglobulin G (IgG) antibodies represent an advisable tool to reach this goal, especially for the still poorly define
Autor:
Eric Destexhe, Sarah Paris-Robidas, Charlotte Dubé, Nathalie Landry, Sonia Trépanier, Iryna Primakova, Brian J. Ward
Publikováno v:
Reproductive Toxicology (Elmsford, N.y.)
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection resulting in the coronavirus disease 2019 (COVID-19) has afflicted tens of millions of people in a worldwide pandemic. A recently developed recombinant Plant-Derived Virus-Like Pa
Autor:
Jamil Yousef, Malin Jönsson, My Hedhammar, Sara Mravinacova, Anna Månberg, Peter Nilsson, Elisa Pin, Sebastian Havervall, Sophia Hober, Jonas Klingström, Wanda Christ, Cecilia Hellström, Charlotte Thålin, Hanna Tegel
Publikováno v:
New Biotechnology
Highly accurate serological tests are key to assessing the prevalence of SARS-CoV-2 antibodies and the level of immunity in the population. This is important to predict the current and future status of the pandemic. With the recent emergence of new a
Autor:
Almas Hanif Mulla, Jonaid Ahmad Malik, Turki Al Hagbani, Saleh Alghamdi, Sirajudheen Anwar, Mohammed Abrar Ubaid, Khaled Almansour, Tahmeena Farooqi
Publikováno v:
Journal of Infection and Public Health
Journal of Infection and Public Health, Vol 14, Iss 10, Pp 1299-1312 (2021)
Journal of Infection and Public Health, Vol 14, Iss 10, Pp 1299-1312 (2021)
Background: Over the last two decades, humanity has observed the extraordinary anomaly caused by novel, weird coronavirus strains, such as severe acute respiratory syndrome (SARS) and Middle East respiratory syndrome (MERS). As the severe acute respi
Autor:
Jin Gyu Jung, Sunghyun Kim, Bum Soo Kim, Anca Streinu-Cercel, Oana Săndulescu, Da Bee Jeon, Adrian Streinu-Cercel, Seul Gi Lee, Sang Joon Lee, Yeon Sook Kim, Yeo Jin Lee, Jin Yong Kim, Yeon Mi Lee, Min Kyung Kim, Jae-Hyeong Park, Jang Hee Hong, Jeong Eun Park, Young Rock Jang, Na Hyun Jung
Publikováno v:
Clinical Therapeutics
PURPOSE: Neutralizing antibodies can reduce SARS-CoV-2 cellular entry, viral titers, and pathologic damage. CT-P59 (regdanvimab), a SARS-CoV-2 neutralizing monoclonal antibody, was examined in 2 randomized, double-blind, placebo-controlled, single as
Publikováno v:
Progress in Biophysics and Molecular Biology
The coronavirus disease (COVID-19) arises from the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) which is an enveloped RNA virus. COVID-19 has rapidly spread throughout the world by infecting more than 143 million people and causing 3.
Autor:
Pratool Bharti, Prajkta Chivte, Elizabeth R. Gaillard, Venkata Devesh Reddy Seethi, Shrihari S. Kadkol, Zane LaCasse, Joshua Bland
Publikováno v:
Journal of Mass Spectrometry and Advances in the Clinical Lab
Journal of Mass Spectrometry and Advances in the Clinical Lab, Vol 21, Iss, Pp 31-41 (2021)
Journal of Mass Spectrometry and Advances in the Clinical Lab, Vol 21, Iss, Pp 31-41 (2021)
More than a year after the COVID-19 pandemic was declared, the need still exists for accurate, rapid, inexpensive and non-invasive diagnostic methods that yield high specificity and sensitivity towards the current and newly emerging SARS-CoV-2 strain