The Platform Trial In COVID-19 priming and BOOsting (PICOBOO): the immunogenicity, reactogenicity, and safety of licensed COVID-19 vaccinations administered as a second booster in BNT162b2 primed individuals aged 18-<50 and 50-<70 years old.

Autor: McLeod C; Wesfarmers Centre of Vaccines and Infectious Diseases, The Kids Research Institute of AustraliavAustralia; Infectious Diseases Department, Perth Children's Hospital, Nedlands, Australia; Centre for Child Health Research, University of Western Australia, Crawley, Australia. Electronic address: charlie.mcleod@health.wa.gov.au., Dymock M; Wesfarmers Centre of Vaccines and Infectious Diseases, The Kids Research Institute of AustraliavAustralia; School of Population and Global Health, University of Western Australia, Nedlands, Australia., Flanagan KL; Tasmanian Vaccine Trial Centre, Clifford Craig Foundation, Launceston General Hospital, Tasmania, Australia; School of Health Sciences, College of Health and Medicine, University of Tasmania, Launceston, Tasmania, Australia; School of Health and Biomedical Sciences, Royal Melbourne Institute of Technology University (RMIT), Melbourne, Australia., Plebanski M; School of Health and Biomedical Sciences, Royal Melbourne Institute of Technology University (RMIT), Melbourne, Australia., Marshall HS; Women's and Children's Health Network, North Adelaide, Australia; Robinson Research Institute and Adelaide Medical School, The University of Adelaide, Australia., Estcourt MJ; Sydney School of Public Health, Faculty of Medicine and Health, University of Sydney, Australia., Wadia U; Wesfarmers Centre of Vaccines and Infectious Diseases, The Kids Research Institute of AustraliavAustralia; Infectious Diseases Department, Perth Children's Hospital, Nedlands, Australia; Centre for Child Health Research, University of Western Australia, Crawley, Australia., Tjiam MC; Wesfarmers Centre of Vaccines and Infectious Diseases, The Kids Research Institute of AustraliavAustralia., Blyth CC; Wesfarmers Centre of Vaccines and Infectious Diseases, The Kids Research Institute of AustraliavAustralia; Infectious Diseases Department, Perth Children's Hospital, Nedlands, Australia; Centre for Child Health Research, University of Western Australia, Crawley, Australia; Department of Microbiology, Pathwest Laboratory Medicine WA, QEII Medical Centre, Nedlands, Australia., Subbarao K; WHO Collaborating Centre for Reference and Research on Influenza, University of Melbourne, Parkville, Victoria; Department of Microbiology and Immunology, University of Melbourne at the Peter Doherty Institute for Infection and Immunity, Melbourne, Australia., Mordant FL; Department of Microbiology and Immunology, University of Melbourne at the Peter Doherty Institute for Infection and Immunity, Melbourne, Australia., Nicholson S; Victorian Infectious Diseases Reference Laboratory, The Royal Melbourne Hospital at the Peter Doherty Institute for Infection and Immunity, Melbourne, Australia; Department of Infectious Diseases, University of Melbourne at the Peter Doherty Institute for Infection and Immunity, Melbourne, Australia., Cain N; Department of Microbiology and Immunology, University of Melbourne at the Peter Doherty Institute for Infection and Immunity, Melbourne, Australia., Brizuela R; Department of Microbiology and Immunology, University of Melbourne at the Peter Doherty Institute for Infection and Immunity, Melbourne, Australia., Faust SN; National Institute of Health Research Southampton Clinical Research Facility and Biomedical Research Centre, University Hospital Southampton NHS Foundation Trust, Southampton, United Kingdom; Faculty of Medicine and Institute for Life Sciences, University of Southampton, United Kingdom., Thornton RB; Wesfarmers Centre of Vaccines and Infectious Diseases, The Kids Research Institute of AustraliavAustralia; Centre for Child Health Research, University of Western Australia, Crawley, Australia., Ellis Z; Wesfarmers Centre of Vaccines and Infectious Diseases, The Kids Research Institute of AustraliavAustralia., Mckenzie A; The Kids Research Institute of Australia, Nedlands, Australia., Marsh JA; Wesfarmers Centre of Vaccines and Infectious Diseases, The Kids Research Institute of AustraliavAustralia; Centre for Child Health Research, University of Western Australia, Crawley, Australia., Snelling TL; Sydney School of Public Health, Faculty of Medicine and Health, University of Sydney, Australia., Richmond PC; Wesfarmers Centre of Vaccines and Infectious Diseases, The Kids Research Institute of AustraliavAustralia; Centre for Child Health Research, University of Western Australia, Crawley, Australia; Centre for Child Health Research, University of Western Australia, Crawley, Australia; General Paediatrics and Immunology Departments, Perth Children's Hospital, Nedlands, Australia.

Publikováno v: The Journal of infection [J Infect] 2024 Nov 14, pp. 106346. Date of Electronic Publication: 2024 Nov 14.

Safety, tolerability, and effect of a single aural dose of Dornase alfa at the time of ventilation tube surgery for otitis media: A Phase 1b double randomized control trial.

Autor: Thornton RB; Centre for Child Health Research, University of Western Australia, Perth, Western Australia, Australia; Wesfarmers Centre of Vaccines and Infectious Diseases, Telethon Kids Institute, Perth, Western Australia, Australia. Electronic address: ruth.thornton@uwa.edu.au., Jeffares S; Wesfarmers Centre of Vaccines and Infectious Diseases, Telethon Kids Institute, Perth, Western Australia, Australia., Seppanen E; Wesfarmers Centre of Vaccines and Infectious Diseases, Telethon Kids Institute, Perth, Western Australia, Australia., Jacoby P; Wesfarmers Centre of Vaccines and Infectious Diseases, Telethon Kids Institute, Perth, Western Australia, Australia., Kirkham LS; Centre for Child Health Research, University of Western Australia, Perth, Western Australia, Australia; Wesfarmers Centre of Vaccines and Infectious Diseases, Telethon Kids Institute, Perth, Western Australia, Australia., Bennett H; Kids Hear Diagnostic Audiology, Perth, Western Australia, Australia., Coates HL; Wesfarmers Centre of Vaccines and Infectious Diseases, Telethon Kids Institute, Perth, Western Australia, Australia., Vijayasekaran S; Child Health Research Network, Perth Children's Hospital, Perth, Western Australia, Australia; School of Medicine, University of Western Australia, Perth, Western Australia, Australia., Brennan-Jones CG; Wesfarmers Centre of Vaccines and Infectious Diseases, Telethon Kids Institute, Perth, Western Australia, Australia; Child Health Research Network, Perth Children's Hospital, Perth, Western Australia, Australia; School of Allied Health, Faculty of Health Sciences, Curtin University, Perth, Australia., Richmond PC; Wesfarmers Centre of Vaccines and Infectious Diseases, Telethon Kids Institute, Perth, Western Australia, Australia; Child Health Research Network, Perth Children's Hospital, Perth, Western Australia, Australia; School of Medicine, University of Western Australia, Perth, Western Australia, Australia.

Publikováno v: International journal of pediatric otorhinolaryngology [Int J Pediatr Otorhinolaryngol] 2024 Feb; Vol. 177, pp. 111832. Date of Electronic Publication: 2023 Dec 21.

Core protocol for the adaptive Platform Trial In COVID-19 Vaccine priming and BOOsting (PICOBOO).

Autor: McLeod C; Wesfarmers Centre of Vaccines and Infectious Diseases, Telethon Kids Institute, Nedlands, Australia. charlie.mcleod@health.wa.gov.au.; Centre for Child Health Research, The University of Western Australia, Crawley, Australia. charlie.mcleod@health.wa.gov.au.; Infectious Diseases Department, Perth Children's Hospital, Nedlands, Australia. charlie.mcleod@health.wa.gov.au., Ramsay J; Wesfarmers Centre of Vaccines and Infectious Diseases, Telethon Kids Institute, Nedlands, Australia., Flanagan KL; Tasmanian Vaccine Trial Centre, Clifford Craig Foundation, Launceston General Hospital, Launceston, TAS, Australia.; School of Health Sciences, College of Health and Medicine, University of Tasmania, Launceston, TAS, Australia.; School of Health and Biomedical Sciences, Royal Melbourne Institute of Technology University (RMIT), Melbourne, VIC, Australia., Plebanski M; School of Health and Biomedical Sciences, Royal Melbourne Institute of Technology University (RMIT), Melbourne, VIC, Australia., Marshall H; Women's and Children's Health Network, North Adelaide, Australia.; Robinson Research Institute and Adelaide Medical School, The University of Adelaide, Adelaide, Australia., Dymock M; Wesfarmers Centre of Vaccines and Infectious Diseases, Telethon Kids Institute, Nedlands, Australia., Marsh J; Wesfarmers Centre of Vaccines and Infectious Diseases, Telethon Kids Institute, Nedlands, Australia., Estcourt MJ; Sydney School of Public Health, Faculty of Medicine and Health, University of Sydney, Camperdown, Australia., Wadia U; Wesfarmers Centre of Vaccines and Infectious Diseases, Telethon Kids Institute, Nedlands, Australia.; Centre for Child Health Research, The University of Western Australia, Crawley, Australia.; Infectious Diseases Department, Perth Children's Hospital, Nedlands, Australia., Williams PCM; Sydney School of Public Health, Faculty of Medicine and Health, University of Sydney, Camperdown, Australia.; Department of Immunology and Infectious Diseases, Sydney Children's Hospital Network, Westmead, Australia.; School of Women and Children's Health, UNSW, Kensington, Australia., Tjiam MC; Wesfarmers Centre of Vaccines and Infectious Diseases, Telethon Kids Institute, Nedlands, Australia.; Centre for Child Health Research, The University of Western Australia, Crawley, Australia., Blyth C; Wesfarmers Centre of Vaccines and Infectious Diseases, Telethon Kids Institute, Nedlands, Australia.; Centre for Child Health Research, The University of Western Australia, Crawley, Australia.; Infectious Diseases Department, Perth Children's Hospital, Nedlands, Australia.; Division of Paediatrics, School of Medicine, University of Western Australia, Crawley, Australia., Subbarao K; WHO Collaborating Centre for Reference and Research On Influenza, University of Melbourne, Parkville, VIC, Australia., Nicholson S; Serology Laboratory, Victorian Infectious Diseases Research Laboratory, Melbourne, Australia., Faust S; Southampton Clinical Research Facility and Biomedical Research Centre, National Institute of Health Research, University Hospital Southampton NHS Foundation Trust, Southampton, UK.; Faculty of Medicine and Institute for Life Sciences, University of Southampton, Southampton, UK., Thornton RB; Wesfarmers Centre of Vaccines and Infectious Diseases, Telethon Kids Institute, Nedlands, Australia.; Centre for Child Health Research, The University of Western Australia, Crawley, Australia., Mckenzie A; Wesfarmers Centre of Vaccines and Infectious Diseases, Telethon Kids Institute, Nedlands, Australia., Snelling TL; Sydney School of Public Health, Faculty of Medicine and Health, University of Sydney, Camperdown, Australia., Richmond P; Wesfarmers Centre of Vaccines and Infectious Diseases, Telethon Kids Institute, Nedlands, Australia.; Centre for Child Health Research, The University of Western Australia, Crawley, Australia.; Division of Paediatrics, School of Medicine, University of Western Australia, Crawley, Australia.; General Paediatrics and Immunology Departments, Perth Children's Hospital, Nedlands, Australia.

Publikováno v: Trials [Trials] 2023 Mar 18; Vol. 24 (1), pp. 202. Date of Electronic Publication: 2023 Mar 18.

We should not underestimate the role of biofilms in persistent (chronic) bronchitis - Authors' reply.

Autor: Marsh RL; Child Health Division, Menzies School of Health Research, Charles Darwin University, Darwin, NT 0810, Australia. Electronic address: robyn.marsh@menzies.edu.au., Binks MJ; Child Health Division, Menzies School of Health Research, Charles Darwin University, Darwin, NT 0810, Australia., Smith-Vaughan HC; Child Health Division, Menzies School of Health Research, Charles Darwin University, Darwin, NT 0810, Australia; School of Medicine, Griffith University, Southport, QLD, Australia., Janka M; Wesfarmers Centre of Vaccines and Infectious Diseases, Telethon Kids Institute, Perth, WA, Australia., Clark S; Wesfarmers Centre of Vaccines and Infectious Diseases, Telethon Kids Institute, Perth, WA, Australia; School of Medicine, Division of Paediatrics, University of Western Australia, Perth, WA, Australia., Richmond P; Wesfarmers Centre of Vaccines and Infectious Diseases, Telethon Kids Institute, Perth, WA, Australia; School of Medicine, Division of Paediatrics, University of Western Australia, Perth, WA, Australia., Chang AB; Child Health Division, Menzies School of Health Research, Charles Darwin University, Darwin, NT 0810, Australia; Department of Respiratory and Sleep Medicine, Queensland Children's Hospital, Brisbane, QLD, Australia; Australian Centre for Health Services Innovation, Queensland University of Technology, Brisbane, QLD, Australia., Thornton RB; Wesfarmers Centre of Vaccines and Infectious Diseases, Telethon Kids Institute, Perth, WA, Australia; School of Biomedical Science, University of Western Australia, Perth, WA, Australia.

Publikováno v: The Lancet. Microbe [Lancet Microbe] 2022 Sep; Vol. 3 (9), pp. e648. Date of Electronic Publication: 2022 Jul 04.

Predominant Bacterial and Viral Otopathogens Identified Within the Respiratory Tract and Middle Ear of Urban Australian Children Experiencing Otitis Media Are Diversely Distributed.

Autor: Ngo CC; John Curtin School of Medical Research, College of Health and Medicine, Australian National University, Canberra, ACT, Australia., Massa HM; School of Pharmacy and Medical Sciences, Griffith University, Gold Coast, QLD, Australia., McMonagle BA; School of Medicine and Dentistry, Griffith University, Gold Coast, QLD, Australia.; Pindara Private Hospital, Ramsay Health Care, Gold Coast, QLD, Australia., Perry CF; School of Clinical Medicine, Faculty of Medicine, University of Queensland, Brisbane, QLD, Australia.; Otolaryngology, Head and Neck Surgery Department, Queensland Children's Hospital, Brisbane, QLD, Australia., Nissen MD; Child Health Research Centre, Faculty of Medicine, University of Queensland, Brisbane, QLD, Australia., Sloots TP; Child Health Research Centre, Faculty of Medicine, University of Queensland, Brisbane, QLD, Australia., Thornton RB; Centre for Child Health Research, University of Western Australia, Perth, WA, Australia.; Wesfarmers Centre of Vaccines and Infectious Disease, Telethon Kids Institute, Perth, WA, Australia., Cripps AW; School of Medicine and Dentistry, Griffith University, Gold Coast, QLD, Australia.

Publikováno v: Frontiers in cellular and infection microbiology [Front Cell Infect Microbiol] 2022 Mar 11; Vol. 12, pp. 775535. Date of Electronic Publication: 2022 Mar 11 (Print Publication: 2022).