Zobrazeno 1 - 4
of 4
pro vyhledávání: '"RASSF, RAS association domain family"'
Autor:
Christoph Wittich, Claus A. M. Seidel, Radovan Dvorsky, Soheila Rezaei Adariani, Farhad Bazgir, Ehsan Amin, Mohammad Reza Ahmadian, Neda S. Kazemein Jasemi
Publikováno v:
The Journal of Biological Chemistry
RAS effectors specifically interact with GTP-bound RAS proteins to link extracellular signals to downstream signaling pathways. These interactions rely on two types of domains, called RAS-binding (RB) and RAS association (RA) domains, which share com
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c908bf66f01ab88e26b2531338812873
http://europepmc.org/articles/PMC8163975
http://europepmc.org/articles/PMC8163975
Publikováno v:
The Journal of Biological Chemistry
Ras-association domain family (RASSF) proteins are encoded by numerous tumor suppressor genes that frequently become silenced in human cancers. RASSF10 is downregulated by promoter hypermethylation in cancers and has been shown to inhibit cell prolif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29d5f6290d3c05db565036ae36f08109
https://doi.org/10.1016/j.jbc.2021.100935
https://doi.org/10.1016/j.jbc.2021.100935
Autor:
David J. Adams, Louise van der Weyden
Publikováno v:
Biochimica et Biophysica Acta
Ras proteins play a direct causal role in human cancer with activating mutations in Ras occurring in approximately 30% of tumours. Ras effectors also contribute to cancer, as mutations occur in Ras effectors, notably B-Raf and PI3-K, and drugs blocki
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3df35b2ad3b4fa28754482b44e21731
Autor:
Victoria Sherwood, Andrew Ward, Amy Flaxman, Andrew D. Chalmers, Farida Latif, Asha Recino, Wendy N. Cooper
Publikováno v:
Recino, A, Sherwood, V, Flaxman, A, Cooper, WN, Latif, F, Ward, A & Chalmers, A D 2010, ' Human RASSF7 regulates the microtubule cytoskeleton and is required for spindle formation, Aurora B activation and chromosomal congression during mitosis ' Biochemical Journal, vol. 430, no. 2, pp. 207-213 . https://doi.org/10.1042/BJ20100883
Biochemical Journal
Biochemical Journal
RASSF7, a member of the N-terminal Ras association domain family, has increased expression in various cancers and, on the basis of our previous work in Xenopus embryos, may be a regulator of mitosis. In the present study, we address, for the first ti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ca9de14a9faae70c536fed79d1ee658
https://purehost.bath.ac.uk/ws/files/45393414/Recino_et_al_2010.pdf
https://purehost.bath.ac.uk/ws/files/45393414/Recino_et_al_2010.pdf
