Zobrazeno 1 - 10
of 70
pro vyhledávání: '"RASHEEBA NIZAM"'
Autor:
Mohammed Dashti, Naser M. Ali, Hussain Alsaleh, Sumi Elsa John, Rasheeba Nizam, Fahd Al-Mulla, Thangavel Alphonse Thanaraj
Publikováno v:
Frontiers in Endocrinology, Vol 15 (2024)
BackgroundThe Kuwaiti and Qatari populations have a high prevalence of obesity, a major risk factor for various metabolic disorders. Previous studies have independently explored mitochondrial DNA (mtDNA) variations and their association with obesity
Externí odkaz:
https://doaj.org/article/92b674ae9c274b6d89347513b9c5fc19
Autor:
Rasheeba Nizam, Md Zubbair Malik, Sindhu Jacob, Osama Alsmadi, Heikki A. Koistinen, Jaakko Tuomilehto, Hessa Alkandari, Fahd Al-Mulla, Thangavel Alphonse Thanaraj
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionIncreasing evidence from human and animal model studies indicates the significant role of microRNAs (miRNAs) in pancreatic beta cell function, insulin signaling, immune responses, and pathogenesis of type 1 diabetes (T1D).MethodsWe aimed,
Externí odkaz:
https://doaj.org/article/4ee63224ae1a42cbb189ece9cb942b84
Autor:
Mohammed Dashti, Md Zubbair Malik, Abdullah Al-Matrouk, Saeeda Bhatti, Rasheeba Nizam, Sindhu Jacob, Fahd Al-Mulla, Thangavel Alphonse Thanaraj
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Objective: This study explores the frequency of human leukocyte antigen (HLA) genes, particularly HLA-B alleles, within the Kuwaiti population. We aim to identify alleles with known associations to adverse drug reactions (ADRs) based on existing lite
Externí odkaz:
https://doaj.org/article/52d1ea68d68e4045bef5926ea7ca5cad
Autor:
Texy Jacob, Sardar Sindhu, Amal Hasan, Md. Zubbair Malik, Hossein Arefanian, Fatema Al-Rashed, Rasheeba Nizam, Shihab Kochumon, Reeby Thomas, Fatemah Bahman, Steve Shenouda, Ajit Wilson, Nadeem Akther, Areej Al-Roub, Nermeen Abukhalaf, Shaima Albeloushi, Mohamed Abu-Farha, Ashraf Al Madhoun, Fawaz Alzaid, Thangavel Alphonse Thanaraj, Heikki A. Koistinen, Jaakko Tuomilehto, Fahd Al-Mulla, Rasheed Ahmad
Publikováno v:
Frontiers in Microbiology, Vol 15 (2024)
High-fat diets (HFDs) shape the gut microbiome and promote obesity, inflammation, and liver steatosis. Fish and soybean are part of a healthy diet; however, the impact of these fats, in the absence of sucrose, on gut microbial dysbiosis and its assoc
Externí odkaz:
https://doaj.org/article/d3ab3726b78f47ddbc7105c15171b775
Autor:
Mohammed Dashti, Md Zubbair Malik, Rasheeba Nizam, Sindhu Jacob, Fahd Al-Mulla, Thangavel Alphonse Thanaraj
Publikováno v:
Frontiers in Genetics, Vol 15 (2024)
Introduction: HLA typing is a critical tool in both clinical and research applications at the individual and population levels. Benchmarking studies have indicated HLA-HD as the preferred tool for accurate and comprehensive HLA allele calling. The ad
Externí odkaz:
https://doaj.org/article/f17211757f174d96acbe76b890d8b8ef
Autor:
Prashantha Hebbar, Rasheeba Nizam, Sumi Elsa John, Dinu Antony, Mohammad Dashti, Arshad Channanath, Azza Shaltout, Hessa Al-Khandari, Heikki A. Koistinen, Jaakko Tuomilehto, Osama Alsmadi, Thangavel Alphonse Thanaraj, Fahd Al-Mulla
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-16 (2023)
Abstract Type 1 diabetes (T1D) is characterized by the progressive destruction of pancreatic β-cells, leading to insulin deficiency and lifelong dependency on exogenous insulin. Higher estimates of heritability rates in monozygotic twins, followed b
Externí odkaz:
https://doaj.org/article/eb2a643ae53743f9b4beaaeb1e0a62cf
Autor:
Shihab Kochumon, Md. Zubbair Malik, Sardar Sindhu, Hossein Arefanian, Texy Jacob, Fatemah Bahman, Rasheeba Nizam, Amal Hasan, Reeby Thomas, Fatema Al-Rashed, Steve Shenouda, Ajit Wilson, Shaima Albeloushi, Nourah Almansour, Ghadeer Alhamar, Ashraf Al Madhoun, Fawaz Alzaid, Thangavel Alphonse Thanaraj, Heikki A. Koistinen, Jaakko Tuomilehto, Fahd Al-Mulla, Rasheed Ahmad
Publikováno v:
Nutrients, Vol 16, Iss 12, p 1929 (2024)
Background: High-fat diets cause gut dysbiosis and promote triglyceride accumulation, obesity, gut permeability changes, inflammation, and insulin resistance. Both cocoa butter and fish oil are considered to be a part of healthy diets. However, their
Externí odkaz:
https://doaj.org/article/c0a5b45d853f49d2b47ebc0a3c550022
Autor:
Hossein Arefanian, Ashraf Al Madhoun, Fatema Al-Rashed, Fawaz Alzaid, Fatemah Bahman, Rasheeba Nizam, Mohammed Alhusayan, Sumi John, Sindhu Jacob, Michayla R. Williams, Nermeen Abukhalaf, Steve Shenouda, Shibu Joseph, Halemah AlSaeed, Shihab Kochumon, Anwar Mohammad, Lubaina Koti, Sardar Sindhu, Mohamed Abu-Farha, Jehad Abubaker, Thangavel Alphonse Thanaraj, Rasheed Ahmad, Fahd Al-Mulla
Publikováno v:
Cells, Vol 13, Iss 11, p 949 (2024)
This study unveils verapamil’s compelling cytoprotective and proliferative effects on pancreatic β-cells amidst diabetic stressors, spotlighting its unforeseen role in augmenting cholecystokinin (CCK) expression. Through rigorous investigations em
Externí odkaz:
https://doaj.org/article/d5c54f4e6884425089959cb62cb3ac2c
Autor:
Fatema Al-Rashed, Hossein Arefanian, Ashraf Al Madhoun, Fatemah Bahman, Sardar Sindhu, Halemah AlSaeed, Texy Jacob, Reeby Thomas, Areej Al-Roub, Fawaz Alzaid, MD Zubbair Malik, Rasheeba Nizam, Thangavel Alphonse Thanaraj, Fahd Al-Mulla, Yusuf A. Hannun, Rasheed Ahmad
Publikováno v:
Cells, Vol 13, Iss 5, p 463 (2024)
Non-alcoholic fatty liver disease (NAFLD) is manifested by hepatic steatosis, insulin resistance, hepatocyte death, and systemic inflammation. Obesity induces steatosis and chronic inflammation in the liver. However, the precise mechanism underlying
Externí odkaz:
https://doaj.org/article/84981e0dc4324011a11e490c5b23e6a1
Autor:
Fahd Al-Mulla, Doha Alhomaidah, Mohamed Abu-Farha, Amal Hasan, Irina Al-Khairi, Rasheeba Nizam, Rawan Alqabandi, Hessa Alkandari, Jehad Abubaker
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Type 1 diabetes (T1D) incidence has increased globally over the last decades, alongside other autoimmune diseases. Early screening of individuals at risk of developing T1D is vital to facilitate appropriate interventions and improve patient outcomes.
Externí odkaz:
https://doaj.org/article/0e56236f880c4a5082569b9ea1190f64