Zobrazeno 1 - 10
of 27
pro vyhledávání: '"RAS Superfamily Protein"'
Publikováno v:
Oncology Research
Rap2B, belonging to the Ras superfamily, has been implicated in cancer development and functions as a tumor promoter. However, the role of Rap2B in cervical cancer is unknown. In this study, we investigated the expression pattern and biological funct
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::084e3fbcad794c66e0955cf162936421
https://doi.org/10.3727/096504017x14912172235777
https://doi.org/10.3727/096504017x14912172235777
Autor:
Da Jia, Xin Sun, Yuping Tan, Xiaoyang Shen, Qingxiang Sun, Yuekang Zhang, Aiping Tong, Jinhan Zhou, Qiaoxia Zhou
Ran (Ras-related nuclear protein) plays several important roles in nucleo-cytoplasmic transport, mitotic spindle formation, nuclear envelope/nuclear pore complex assembly, and other diverse functions in the cytoplasm, as well as in cellular transform
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bdfe59663290b7a2e39480244fb00117
Publikováno v:
Proteins: Structure, Function, and Bioinformatics. 79:2467-2474
Proteins often undergo conformational changes when binding to each other. A major fraction of backbone conformational changes involves motion on the protein surface, particularly in loops. Proper accounting for the motion of protein surface loops rep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de13f97bdf23f566a72274c74fd2bdcf
https://doi.org/10.1002/prot.23070
https://doi.org/10.1002/prot.23070
Publikováno v:
Traffic. 10:1561-1568
RAB25, a member of the rat sarcoma (RAS) family of small GTPase, has been implicated in the pathophysiology of ovarian, breast and other cancers. Its role in endosomal transport and recycling of cell-surface receptors and signaling proteins presents
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d2a43550a13fbd8ea0796f318cdf410
https://doi.org/10.1111/j.1600-0854.2009.00969.x
https://doi.org/10.1111/j.1600-0854.2009.00969.x
Publikováno v:
Current Medicinal Chemistry. 16:1355-1365
Signaling through the Rho family of small GTPases has been increasingly investigated for their involvement in a wide variety of diseases such as cardiovascular, pulmonary, and neurological disorders as well as cancer. Rho GTPases are a subfamily of t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::546058fbee0c3cadc76e617e196cadd9
https://doi.org/10.2174/092986709787846569
https://doi.org/10.2174/092986709787846569
Publikováno v:
Gene. 396:116-124
Ras superfamily proteins are key regulators in a wide variety of cellular processes. Previously, they were considered to be specific to eukaryotes, and MglA, a group of obviously different prokaryotic proteins, were recognized as their only prokaryot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a689bf6b413e3ec57ab65b5e10c49b2d
https://doi.org/10.1016/j.gene.2007.03.001
https://doi.org/10.1016/j.gene.2007.03.001
Autor:
Julia Schumacher
Publikováno v:
Botrytis – the Fungus, the Pathogen and its Management in Agricultural Systems ISBN: 9783319233703
Fungi are eukaryotic organisms that are more closely related to animals than to plants and algae, and therefore fungal cells share important features with mammalian cells. This is perhaps most apparent in the signaling cascades that mediate the commu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4c0e8684fd2b402572ced92f3c6f6dc5
https://doi.org/10.1007/978-3-319-23371-0_13
https://doi.org/10.1007/978-3-319-23371-0_13
Autor:
Minutolo, Filippo, Asso, V., Bertini, Simone, Betti, Laura, Ciriaco, M., Danesi, Romano, Gervasi, G., Ghilardi, E., Giovannetti, E., Giannaccini, Gino, Placanica, Giorgio, Prota, G., Rapposelli, Simona, Macchia, Marco
Publikováno v:
Medicinal Chemistry. 1:239-244
Aberrant signalling through the pathways of small GTP-binding proteins, belonging to the Ras superfamily (Ras, Rho, Rac, Cdc42 etc.), occurs in several types of cancer, where mutated Ras accumulates in its GTP-bound active form and causes uncontrolle
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::222b1bd46de1163f3b96432f9be2c0c2
https://doi.org/10.2174/1573406053765512
https://doi.org/10.2174/1573406053765512
Autor:
Dan Theodorescu, Gary Oxford
Publikováno v:
Journal of Urology. 170:1987-1993
Purpose: The prognosis of patients with bladder cancer is strongly dependent on whether the lesion is superficial or invasive at initial presentation. In addition, a significant fraction of patients presenting with superficial disease have invasive t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5b767fb4dc49951ddfb2d94abea9ff05
https://doi.org/10.1097/01.ju.0000088670.02905.78
https://doi.org/10.1097/01.ju.0000088670.02905.78
Autor:
Loan N. Dang, Emily A. Bruce, Benjamin R. King, Jamie A. Kelly, Philip Eisenhauer, David J. Shirley, Jason Botten, Marion E. Weir, Vedran Beganovic, Christopher M. Ziegler, Bryan A. Ballif
Publikováno v:
Journal of Virology
Arenaviruses are negative-strand, enveloped RNA viruses that cause significant human disease. In particular, Junín mammarenavirus (JUNV) is the etiologic agent of Argentine hemorrhagic fever. At present, little is known about the cellular proteins t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6bb180009a8658e8b8b69eb3985d5a9