Zobrazeno 1 - 6
of 6
pro vyhledávání: '"RAPIDE-TKM Trial Team"'
Autor:
Jake Dunning, Foday Sahr, Amanda Rojek, Fiona Gannon, Gail Carson, Baimba Idriss, Thomas Massaquoi, Regina Gandi, Sebatu Joseph, Hassan K Osman, Timothy J G Brooks, Andrew J H Simpson, Ian Goodfellow, Lucy Thorne, Armando Arias, Laura Merson, Lyndsey Castle, Rebecca Howell-Jones, Raul Pardinaz-Solis, Benjamin Hope-Gill, Mauricio Ferri, Jennifer Grove, Mark Kowalski, Kasia Stepniewska, Trudie Lang, John Whitehead, Piero Olliaro, Mohammed Samai, Peter W Horby, RAPIDE-TKM trial team
Publikováno v:
PLoS Medicine, Vol 13, Iss 4, p e1001997 (2016)
BackgroundTKM-130803, a small interfering RNA lipid nanoparticle product, has been developed for the treatment of Ebola virus disease (EVD), but its efficacy and safety in humans has not been evaluated.Methods and findingsIn this single-arm phase 2 t
Externí odkaz:
https://doaj.org/article/5d847f2d4b774f4e93d2e3fad6719689
Autor:
Scott, Janet T, Sharma, Raman, Meredith, Luke W, Dunning, Jake, Moore, Catrin E, Sahr, Foday, Ward, Steve, Goodfellow, Ian, Horby, Peter, RAPIDE-TKM Trial Team
BACKGROUND: TKM-130803 is a specific anti-EBOV therapeutic comprised of two small interfering RNAs (siRNA) siLpol-2 and siVP35-2. The pharmacokinetics (PK) of these siRNAs was defined in Ebola virus disease (EVD) patients, with reference to efficacy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b37388bcbd011e29842067584ef90761
Autor:
Peter Horby, Janet T Scott, Steve A. Ward, Ian Goodfellow, Foday Sahr, Catrin E. Moore, Raman Sharma, Rapide-Tkm trial team, Luke Meredith, Jake Dunning
Publikováno v:
Access Microbiology. 2
TKM-130803 is a specific anti-EBOV therapeutic comprising of two small interfering RNAs (siRNA) siLpol-2 and siVP35-2. The pharmacokinetics (PK) of these siRNAs was defined in Ebola virus disease (EVD) patients. The relationship between PK and patien
Akademický článek
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Autor:
Dunning, Jake, Sahr, Foday, Rojek, Amanda, Gannon, Fiona, Carson, Gail, Idriss, Baimba, Massaquoi, Thomas, Gandi, Regina, Joseph, Sebatu, Osman, Hassan K, Brooks, Timothy JG, Simpson, Andrew JH, Goodfellow, Ian, Thorne, Lucy, Arias, Armando, Merson, Laura, Castle, Lyndsey, Howell-Jones, Rebecca, Pardinaz-Solis, Raul, Hope-Gill, Benjamin, Ferri, Mauricio, Grove, Jennifer, Kowalski, Mark, Stepniewska, Kasia, Lang, Trudie, Whitehead, John, Olliaro, Piero, Samai, Mohammed, Horby, Peter W, RAPIDE-TKM Trial Team
Publikováno v:
PLoS Medicine
Dunning, J, Sahr, F, Rojek, A, Gannon, F, Carson, G, Idriss, B, Massaquoi, T, Gandi, R, Joseph, S, Osman, H K, Brooks, T J G, Simpson, A J H, Goodfellow, I, Thorne, L, Arias Esteban, A, Merson, L, Castle, L, Howell-Jones, R, Pardinaz-Solis, R, Hope-Gill, B, Ferri, M, Grove, J, Kowalski, M, Stepniewska, K, Lang, T, Whitehead, J, Olliaro, P, Samai, M, Horby, P W & von Seidlein, L (ed.) 2016, ' Experimental Treatment of Ebola Virus Disease with TKM-130803: A Single-Arm Phase 2 Clinical Trial ', PLOS Medicine, vol. 13, no. 4, e1001997 . https://doi.org/10.1371/journal.pmed.1001997
PLoS Medicine, Vol 13, Iss 4, p e1001997 (2016)
Dunning, J, Sahr, F, Rojek, A, Gannon, F, Carson, G, Idriss, B, Massaquoi, T, Gandi, R, Joseph, S, Osman, H K, Brooks, T J G, Simpson, A J H, Goodfellow, I, Thorne, L, Arias Esteban, A, Merson, L, Castle, L, Howell-Jones, R, Pardinaz-Solis, R, Hope-Gill, B, Ferri, M, Grove, J, Kowalski, M, Stepniewska, K, Lang, T, Whitehead, J, Olliaro, P, Samai, M, Horby, P W & von Seidlein, L (ed.) 2016, ' Experimental Treatment of Ebola Virus Disease with TKM-130803: A Single-Arm Phase 2 Clinical Trial ', PLOS Medicine, vol. 13, no. 4, e1001997 . https://doi.org/10.1371/journal.pmed.1001997
PLoS Medicine, Vol 13, Iss 4, p e1001997 (2016)
Background TKM-130803, a small interfering RNA lipid nanoparticle product, has been developed for the treatment of Ebola virus disease (EVD), but its efficacy and safety in humans has not been evaluated. Methods and Findings In this single-arm phase
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.