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Haplotype-based, case–control study of the receptor (calcitonin) activity-modifying protein (RAMP) 1 gene in essential hypertension

Autor: Zhen-Yan Fu, Tomohiro Nakayama, Masanori Shimodaira, Tadashi Hoshino, Noriko Aoi, Zhaoxia Wang, Hiromu Naruse, Masayoshi Soma, T Nakazato

Publikováno v: Journal of Human Hypertension. 31:361-365

The adrenomedullin receptor is a complex molecule that comprises the calcitonin-receptor-like receptor (CRLR) and the receptor-activity-modifying protein (RAMP). RAMP1 is a vasodilation factor, and RAMP1-deficient mice (RAMP1(-/-)) exhibit inflammato

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1986dc1fb269c5ca93fe3b78f0f692de
https://doi.org/10.1038/jhh.2016.96

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Sensory Neuropeptides and their Receptors Participate in Mechano-Regulation of Murine Macrophages

Autor: Dominique Muschter, Anna-Sophie Beiderbeck, Christian Kirschneck, Agnes Schröder, Susanne Grässel, Tanja Späth

Publikováno v: International Journal of Molecular Sciences
Volume 20
Issue 3
International Journal of Molecular Sciences, Vol 20, Iss 3, p 503 (2019)

This study aimed to analyze if the sensory neuropeptide SP (SP) and the neurokinin receptor 1 (NK1R) are involved in macrophage mechano-transduction, similar to chondrocytes, and if alpha-calcitonin gene-related peptide (&alpha
CGRP) and the CGR

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e7835cd526513e47e02fc89e44e5f39

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Intermedin is upregulated and has protective roles in a mouse ischemia/reperfusion model

Autor: Wei Jiang, Jian-Ying Liu, Hong-Bo Xin, Chun-Lin Chen, De-Jia Huang, Heng-Yu Zhang, Yan Li

Publikováno v: Hypertension Research. 32:861-868

Intermedin (IMD), a new calcitonin/calcitonin gene-related peptide family peptide with vasodilatory and positive inotropic properties, has multiple functions in regulating cardiovascular homeostasis and is of particular interest in the pathophysiolog

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78ecf4ebed2f926ae1c332831af496bc
https://doi.org/10.1038/hr.2009.120

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STC1 interference on calcitonin family of receptors signaling during osteoblastogenesis via adenylate cyclase inhibition

Autor: Rute C. Félix, Silvia Resende Terra, Leo Anderson Meira Martins, Diogo Onofre Gomes de Souza, João C.R. Cardoso, Fátima Theresinha Costa Rodrigues Guma, Vanessa Schein, Adelino V.M. Canario

Publikováno v: Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP

Stanniocalcin 1 (STC1) and calcitonin gene-related peptide (CGRP) are involved in bone formation/remodeling. Here we investigate the effects of STC1 on functional heterodimer complex CALCRL/RAMP1, expression and activity during osteoblastogenesis. ST

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1fba57fa6957b63cf90075ff492776da

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Haplotype-based case-control study of receptor (calcitonin) activity-modifying protein-1 gene in cerebral infarction

Autor: Masayoshi Soma, Tomohiro Nakayama, Takahiro Naganuma, T Nakazato, Zhaoxia Wang, Kaoru Sugama, Shigeaki Hinohara, Zhen-Yan Fu, Naoyuki Sato, Nobutaka Doba

Publikováno v: Journal of human hypertension. 24(5)

Calcitonin gene-related peptide (CGRP) receptor is a complex molecule that consists of calcitonin receptor-like receptor and receptor activity-modifying protein-1 (RAMP1). It was recently reported that RAMP1-deficient mice (RAMP1(−/−)) showed inf

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6f75159433f992b2dd3504e8dc1d8f4
https://pubmed.ncbi.nlm.nih.gov/19710695

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Calcitonin gene-related peptide receptor activation by receptor activity-modifying protein-1 gene transfer to vascular smooth muscle cells

Autor: Ian M. Dickerson, Zhongming Zhang, Andrew F. Russo

Publikováno v: Endocrinology. 147(4)

The neuropeptide calcitonin gene-related peptide (CGRP) is a potent vasodilator that plays a protective role in the cardiovascular system. The receptor for CGRP is an unusual complex of the G protein-coupled calcitonin-like receptor and an obligate r

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15aae0887642430e1873c9ddd05d4181
https://pubmed.ncbi.nlm.nih.gov/16373421

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Activation of calcitonin gene-related peptide signaling through the prostaglandin E2-EP1/EP2/EP4 receptor pathway in synovium of knee osteoarthritis patients

Autor: Hisako Fujimaki, Toshihide Matsumoto, Atsushi Minatani, Masashi Takaso, Jun Aikawa, Masayuki Miyagi, Kenji Onuma, Dai Iwase, Kentaro Uchida, Shotaro Takano, Gen Inoue

Publikováno v: Journal of Orthopaedic Surgery and Research

Background Calcitonin gene-related peptide (CGRP) is a 37-amino-acid vasodilatory neuropeptide that binds to receptor activity-modifying protein 1 (RAMP1) and the calcitonin receptor-like receptor (CLR). Clinical and preclinical evidence suggests tha

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::634896d889b58b3804831a8cf2efbcd6

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