Zobrazeno 1 - 10
of 17
pro vyhledávání: '"RAMESH KUDIRA"'
Autor:
RAMESH KUDIRA, Bal Sharma, Mary Mullen, Sujit Mohanty, Bryan Donnelly, Gregory Tiao, Alexander Miethke
Publikováno v:
Bio-Protocol, Vol 11, Iss 20 (2021)
Cholangiocytes are epithelial cells lining the intrahepatic and extrahepatic bile ducts. Cholangiocytes perform key physiological functions in the liver. Bile synthesized by hepatocytes is secreted into bile canaliculi, further stored in the gallblad
Externí odkaz:
https://doaj.org/article/20084323a4bb4acd92fc0e485aeadc7b
Publikováno v:
Journal of Cellular Physiology. 237:4215-4225
Liver depleted of hepatic stellate cells (HSCs) is resistant to ischemia/reperfusion-, concanavalin A-, and acetaminophen-induced acute injury. Whether HSCs regulate carbon tetrachloride (CCl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43e534a16210e85bd91f7dfacc85d72a
https://doi.org/10.1002/jcp.30877
https://doi.org/10.1002/jcp.30877
Autor:
Tiffany Shi, Astha Malik, Annika Yang vom Hofe, Louis Matuschek, Mary Mullen, Celine S. Lages, Ramesh Kudira, Ruchi Singh, Wujuan Zhang, Kenneth D.R. Setchell, David Hildeman, Chandrashekhar Pasare, Brandee Wagner, Alexander G. Miethke
Publikováno v:
Science Translational Medicine. 14
Immune-mediated bile duct epithelial injury and toxicity of retained hydrophobic bile acids drive disease progression in fibrosing cholangiopathies such as biliary atresia or primary sclerosing cholangitis. Emerging therapies include pharmacological
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0547f58210a5bf4ebeb59b9c8f4c43bd
https://doi.org/10.1126/scitranslmed.abi4354
https://doi.org/10.1126/scitranslmed.abi4354
Publikováno v:
BIO-PROTOCOL. 12
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5b574381e6544ed307bf47fb7b2b7a4b
https://doi.org/10.21769/bioprotoc.4400
https://doi.org/10.21769/bioprotoc.4400
Autor:
Mary P. Mullen, Alexander Miethke, Gregory M. Tiao, Bal Krishan Sharma, Bryan Donnelly, Ramesh Kudira, Sujit K. Mohanty
Publikováno v:
Bio Protoc
Cholangiocytes are epithelial cells lining the intrahepatic and extrahepatic bile ducts. Cholangiocytes perform key physiological functions in the liver. Bile synthesized by hepatocytes is secreted into bile canaliculi, further stored in the gallblad
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87aae72665be37d0dd7fbe0a92519bbf
https://europepmc.org/articles/PMC8554810/
https://europepmc.org/articles/PMC8554810/
Autor:
Jiang Wang, Alexander Miethke, Tong Wu, Alok K. Verma, Matthew Kofron, Chandrashekhar R. Gandhi, Akanksha Sharma, Ramesh Kudira
Publikováno v:
Hepatology
BACKGROUND AND AIMS: During liver injury, quiescent hepatic stellate cells (qHSCs) transdifferentiate into proliferative and fibrogenic activated myofibroblastic phenotype (activated hepatic stellate cell; aHSCs) expressing smooth muscle α-actin (α
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54f0e258482a0be9c0e1154dd8dee7d9
https://europepmc.org/articles/PMC8009050/
https://europepmc.org/articles/PMC8009050/
Autor:
Simon Lam, Celine S. Lages, Amy Taylor, Julia Simmons, Rebekah Karns, Claire A. Chougnet, Ramesh Kudira, Maha Almanan, Alexander Miethke, Kumar Shanmukhappa, Tiffany Shi, Alexandra N. Carey
Publikováno v:
Hepatology. 68:1905-1921
In the multidrug resistance protein 2 (Mdr2)-/- mouse model, low phospholipid bile instigates biliary epithelial injury, sterile inflammation, and fibrosis, thereby recapitulating disease mechanisms implicated in biliary atresia (BA) and primary scle
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0f61abde74325bbfbe8834b025722fd
https://doi.org/10.1002/hep.30061
https://doi.org/10.1002/hep.30061
Fibrin(ogen) Promotes Immune Cell Infiltration, Dysbiosis and ROS Production in Experimental Colitis
Autor:
Matthew J. Flick, Lindsey E. Romick-Rosendale, Benjamin E Gourley, Leah Rosenfeldt, Olivia Edwards, Miki Watanabe, Ramesh Kudira, David B. Haslam, Joseph S. Palumbo, Bal Krishan Sharma, Rachel Cantrell
Publikováno v:
Blood. 138:443-443
Elevated stool fibrinogen has recently been shown to predict disease course in ulcerative colitis (UC), suggesting that fibrin(ogen) in the colitis microenvironment promotes UC pathogenesis. This conclusion is consistent with previous studies from ou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aba46f004c0508340198e0cfded59931
https://doi.org/10.1182/blood-2021-153148
https://doi.org/10.1182/blood-2021-153148
Autor:
Immaculeta Osuji, Ammar Husami, Kejian Zhang, Duc-Hung Pham, Liva Pfuhler, Kimberley J. Evason, Nelson Matuschek, Mary P. Mullen, Sami Wali, Laura N. Bull, Ramesh Kudira, Jillian L. Ellis, C. Alexander Valencia, Lingfen Xu, Tiffany Shi, Chunyue Yin, Alexander Miethke, Sujit K. Mohanty
Publikováno v:
Gastroenterology
Background & Aims The etiology of cholestasis remains unknown in many children. We surveyed the genome of children with chronic cholestasis for variants in genes not previously associated with liver disease and validated their biological relevance in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36f684f3c4dde129d2f26f52b8dc60b1
https://doi.org/10.1053/j.gastro.2021.03.026
https://doi.org/10.1053/j.gastro.2021.03.026
Autor:
Astha Malik, Louis Matuschek, Tiffany Shi, Mary Mulen, Ramesh Kudira, Ruchi Singh, Mr. Sean Maynor, Brandee Wagner, Alexander Miethke
Publikováno v:
Journal of Hepatology. 73:S194-S195
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ccccbfca81c2c96413c73c01cb0ee3ec
https://doi.org/10.1016/s0168-8278(20)30896-5
https://doi.org/10.1016/s0168-8278(20)30896-5