Zobrazeno 1 - 10
of 2 332
pro vyhledávání: '"RAMACHANDRAN S. VASAN"'
Autor:
Ghislain Rocheleau, Shoa L. Clarke, Gaëlle Auguste, Natalie R. Hasbani, Alanna C. Morrison, Adam S. Heath, Lawrence F. Bielak, Kruthika R. Iyer, Erica P. Young, Nathan O. Stitziel, Goo Jun, Cecelia Laurie, Jai G. Broome, Alyna T. Khan, Donna K. Arnett, Lewis C. Becker, Joshua C. Bis, Eric Boerwinkle, Donald W. Bowden, April P. Carson, Patrick T. Ellinor, Myriam Fornage, Nora Franceschini, Barry I. Freedman, Nancy L. Heard-Costa, Lifang Hou, Yii-Der Ida Chen, Eimear E. Kenny, Charles Kooperberg, Brian G. Kral, Ruth J. F. Loos, Sharon M. Lutz, JoAnn E. Manson, Lisa W. Martin, Braxton D. Mitchell, Rami Nassir, Nicholette D. Palmer, Wendy S. Post, Michael H. Preuss, Bruce M. Psaty, Laura M. Raffield, Elizabeth A. Regan, Stephen S. Rich, Jennifer A. Smith, Kent D. Taylor, Lisa R. Yanek, Kendra A. Young, NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium, Austin T. Hilliard, Catherine Tcheandjieu, Patricia A. Peyser, Ramachandran S. Vasan, Jerome I. Rotter, Clint L. Miller, Themistocles L. Assimes, Paul S. de Vries, Ron Do
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract Whole genome sequences (WGS) enable discovery of rare variants which may contribute to missing heritability of coronary artery disease (CAD). To measure their contribution, we apply the GREML-LDMS-I approach to WGS of 4949 cases and 17,494 c
Externí odkaz:
https://doaj.org/article/06f5575dd28f4c74ac4e7a972d07a02f
Autor:
Patricia E. Miller, Priya Gajjar, Gary F. Mitchell, Sadiya S. Khan, Ramachandran S. Vasan, Martin G. Larson, Gregory D. Lewis, Ravi V. Shah, Matthew Nayor
Publikováno v:
ESC Heart Failure, Vol 11, Iss 5, Pp 3279-3289 (2024)
Abstract Aims New tools are needed to identify heart failure (HF) risk earlier in its course. We evaluated the association of multidimensional cardiopulmonary exercise testing (CPET) phenotypes with subclinical risk markers and predicted long‐term
Externí odkaz:
https://doaj.org/article/27d9174b544d4deca982e05568f0ef56
Autor:
Aya Awwad, Eugene P. Rhee, Morgan Grams, Hernan Rincon Choles, James Sondheimer, Jiang He, Jing Chen, Chi-yuan Hsu, Ramachandran S Vasan, Paul L. Kimmel, Kendra Wulczyn, Anders Berg, Jim Lash, Mengyao Tang, Sahir Kalim, the CRIC Study Investigators
Publikováno v:
BMC Nephrology, Vol 25, Iss 1, Pp 1-11 (2024)
Abstract Background Protein carbamylation, a post-translational protein modification primarily driven by urea, independently associates with adverse clinical outcomes in patients with CKD. Biomarkers used to quantify carbamylation burden have mainly
Externí odkaz:
https://doaj.org/article/9b4ad286cc1e46068593b66e1033a4ab
Autor:
Rebecca Keener, Surya B. Chhetri, Carla J. Connelly, Margaret A. Taub, Matthew P. Conomos, Joshua Weinstock, Bohan Ni, Benjamin Strober, Stella Aslibekyan, Paul L. Auer, Lucas Barwick, Lewis C. Becker, John Blangero, Eugene R. Bleecker, Jennifer A. Brody, Brian E. Cade, Juan C. Celedon, Yi-Cheng Chang, L. Adrienne Cupples, Brian Custer, Barry I. Freedman, Mark T. Gladwin, Susan R. Heckbert, Lifang Hou, Marguerite R. Irvin, Carmen R. Isasi, Jill M. Johnsen, Eimear E. Kenny, Charles Kooperberg, Ryan L. Minster, Take Naseri, Satupa’itea Viali, Sergei Nekhai, Nathan Pankratz, Patricia A. Peyser, Kent D. Taylor, Marilyn J. Telen, Baojun Wu, Lisa R. Yanek, Ivana V. Yang, Christine Albert, Donna K. Arnett, Allison E. Ashley-Koch, Kathleen C. Barnes, Joshua C. Bis, Thomas W. Blackwell, Eric Boerwinkle, Esteban G. Burchard, April P. Carson, Zhanghua Chen, Yii-Der Ida Chen, Dawood Darbar, Mariza de Andrade, Patrick T. Ellinor, Myriam Fornage, Bruce D. Gelb, Frank D. Gilliland, Jiang He, Talat Islam, Stefan Kaab, Sharon L. R. Kardia, Shannon Kelly, Barbara A. Konkle, Rajesh Kumar, Ruth J. F. Loos, Fernando D. Martinez, Stephen T. McGarvey, Deborah A. Meyers, Braxton D. Mitchell, Courtney G. Montgomery, Kari E. North, Nicholette D. Palmer, Juan M. Peralta, Benjamin A. Raby, Susan Redline, Stephen S. Rich, Dan Roden, Jerome I. Rotter, Ingo Ruczinski, David Schwartz, Frank Sciurba, M. Benjamin Shoemaker, Edwin K. Silverman, Moritz F. Sinner, Nicholas L. Smith, Albert V. Smith, Hemant K. Tiwari, Ramachandran S. Vasan, Scott T. Weiss, L. Keoki Williams, Yingze Zhang, Elad Ziv, Laura M. Raffield, Alexander P. Reiner, NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium, TOPMed Hematology and Hemostasis Working Group, TOPMed Structural Variation Working Group, Marios Arvanitis, Carol W. Greider, Rasika A. Mathias, Alexis Battle
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-21 (2024)
Abstract Genome-wide association studies (GWAS) have become well-powered to detect loci associated with telomere length. However, no prior work has validated genes nominated by GWAS to examine their role in telomere length regulation. We conducted a
Externí odkaz:
https://doaj.org/article/3e293e6c932a4a42b553d789d690044b
Autor:
Yuankai Zhang, Xuzhi Wang, Chathurangi H Pathiravasan, Nicole L Spartano, Honghuang Lin, Belinda Borrelli, Emelia J Benjamin, David D McManus, Martin G Larson, Ramachandran S Vasan, Ravi V Shah, Gregory D Lewis, Chunyu Liu, Joanne M Murabito, Matthew Nayor
Publikováno v:
Journal of Medical Internet Research, Vol 26, p e56676 (2024)
BackgroundResting heart rate (HR) and routine physical activity are associated with cardiorespiratory fitness levels. Commercial smartwatches permit remote HR monitoring and step count recording in real-world settings over long periods of time, but t
Externí odkaz:
https://doaj.org/article/e9e5182e9c70429c97c986c03547143c
Autor:
Jonathan G. Amatruda, Ronit Katz, Casey M. Rebholz, Mark J. Sarnak, Orlando M. Gutierrez, Sarah J. Schrauben, Jason H. Greenberg, Josef Coresh, Mary Cushman, Sushrut Waikar, Chirag R. Parikh, Jeffrey R. Schelling, Manasi P. Jogalekar, Joseph V. Bonventre, Ramachandran S. Vasan, Paul L. Kimmel, Joachim H. Ix, Michael G. Shlipak
Publikováno v:
Kidney Medicine, Vol 6, Iss 6, Pp 100834- (2024)
Rationale & Objective: Tubulointerstitial damage is a feature of early chronic kidney disease (CKD), but current clinical tests capture it poorly. Urine biomarkers of tubulointerstitial health may identify risk of CKD. Study Design: Prospective cohor
Externí odkaz:
https://doaj.org/article/6c30c18def6e45a6aa01ef19841e1239
Autor:
Sandhiya Ravichandran, Priya Gajjar, Maura E. Walker, Brenton Prescott, Connie W. Tsao, Mawra Jha, Prashant Rao, Patricia Miller, Martin G. Larson, Ramachandran S. Vasan, Ravi V. Shah, Vanessa Xanthakis, Gregory D. Lewis, Matthew Nayor
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 13, Iss 9 (2024)
Background The relation of cardiorespiratory fitness (CRF) to lifestyle behaviors and factors linked with cardiovascular health remains unclear. We aimed to understand how the American Heart Association's Life's Essential 8 (LE8) score (and its chang
Externí odkaz:
https://doaj.org/article/a8330f7ca0a44f87a7f4dc1a2b839653
Autor:
Rebecca J. Song, Martin G. Larson, Hugo J. Aparicio, J. Michael Gaziano, Peter Wilson, Kelly Cho, Ramachandran S. Vasan, Matthew P. Fox, Luc Djoussé, On Behalf Of the Million Veteran Program
Publikováno v:
BMC Public Health, Vol 23, Iss 1, Pp 1-12 (2023)
Abstract Background There is inconsistent evidence on the association of moderate alcohol consumption and stroke risk in the general population and is not well studied among U.S. Veterans. Furthermore, it is unclear whether primarily drinking beer, w
Externí odkaz:
https://doaj.org/article/041e15c4536e4261b60d9509ea8afa7a
Autor:
Amalie Lykkemark Møller, Ramachandran S. Vasan, Daniel Levy, Charlotte Andersson, Honghuang Lin
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-10 (2023)
Abstract Gene function can be described using various measures. We integrated association studies of three types of omics data to provide insights into the pathophysiology of subclinical coronary disease and myocardial infarction (MI). Using multivar
Externí odkaz:
https://doaj.org/article/c05cd67a155c4e31975f59346a1ecc65
Autor:
Adrienne Tin, Alison E. Fohner, Qiong Yang, Jennifer A. Brody, Gail Davies, Jie Yao, Dan Liu, Ilana Caro, Joni V. Lindbohm, Michael R. Duggan, Osorio Meirelles, Sarah E. Harris, Valborg Gudmundsdottir, Adele M. Taylor, Albert Henry, Alexa S. Beiser, Ali Shojaie, Annabell Coors, Annette L. Fitzpatrick, Claudia Langenberg, Claudia L. Satizabal, Colleen M. Sitlani, Eleanor Wheeler, Elliot M. Tucker-Drob, Jan Bressler, Josef Coresh, Joshua C. Bis, Julián Candia, Lori L. Jennings, Maik Pietzner, Mark Lathrop, Oscar L. Lopez, Paul Redmond, Robert E. Gerszten, Stephen S. Rich, Susan R. Heckbert, Thomas R. Austin, Timothy M. Hughes, Toshiko Tanaka, Valur Emilsson, Ramachandran S. Vasan, Xiuqing Guo, Yineng Zhu, Christophe Tzourio, Jerome I. Rotter, Keenan A. Walker, Luigi Ferrucci, Mika Kivimäki, Monique M. B. Breteler, Simon R. Cox, Stephanie Debette, Thomas H. Mosley, Vilmundur G. Gudnason, Lenore J. Launer, Bruce M. Psaty, Sudha Seshadri, Myriam Fornage
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-14 (2023)
Abstract Identifying circulating proteins associated with cognitive function may point to biomarkers and molecular process of cognitive impairment. Few studies have investigated the association between circulating proteins and cognitive function. We
Externí odkaz:
https://doaj.org/article/8eb6e400abed4b8eba3c10d3a6a5024b