Zobrazeno 1 - 10
of 172
pro vyhledávání: '"RAJEEV RAMAN"'
Autor:
Katarzyna M. Grochowska, Marit Sperveslage, Rajeev Raman, Antonio V. Failla, Dawid Głów, Christian Schulze, Laura Laprell, Boris Fehse, Michael R. Kreutz
Publikováno v:
Cell Reports, Vol 42, Iss 8, Pp 112998- (2023)
Summary: The complex morphology of neurons poses a challenge for proteostasis because the majority of lysosomal degradation machinery is present in the cell soma. In recent years, however, mature lysosomes were identified in dendrites, and a fraction
Externí odkaz:
https://doaj.org/article/c3054975b675454d8630ed3d26b78003
Autor:
Alessandro Dario Confettura, Eleonora Cuboni, Mohamed Rafeet Ammar, Shaobo Jia, Guilherme M. Gomes, PingAn Yuanxiang, Rajeev Raman, Tingting Li, Katarzyna M. Grochowska, Robert Ahrends, Anna Karpova, Alexander Dityatev, Michael R. Kreutz
Publikováno v:
Translational Neurodegeneration, Vol 11, Iss 1, Pp 1-18 (2022)
Abstract Background The metabolic syndrome is a consequence of modern lifestyle that causes synaptic insulin resistance and cognitive deficits and that in interaction with a high amyloid load is an important risk factor for Alzheimer's disease. It ha
Externí odkaz:
https://doaj.org/article/8050b454059242799298a70205d8078a
Publikováno v:
Molecular Brain, Vol 14, Iss 1, Pp 1-12 (2021)
Abstract Jacob is a synapto-nuclear messenger protein that couples NMDAR activity to CREB-dependent gene expression. In this study, we investigated the nuclear distribution of Jacob and report a prominent targeting to the nuclear envelope that requir
Externí odkaz:
https://doaj.org/article/a7fdade68a7246cf928274c363d333d6
Autor:
Maria Andres-Alonso, Mohamed Raafet Ammar, Ioana Butnaru, Guilherme M. Gomes, Gustavo Acuña Sanhueza, Rajeev Raman, PingAn Yuanxiang, Maximilian Borgmeyer, Jeffrey Lopez-Rojas, Syed Ahsan Raza, Nicola Brice, Torben J. Hausrat, Tamar Macharadze, Silvia Diaz-Gonzalez, Mark Carlton, Antonio Virgilio Failla, Oliver Stork, Michaela Schweizer, Eckart D. Gundelfinger, Matthias Kneussel, Christina Spilker, Anna Karpova, Michael R. Kreutz
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-17 (2019)
There is growing evidence that autophagy might serve specialized functions in neurons besides its role in protein homeostasis. In this study, authors demonstrate that axonal retrograde transport of BDNF/TrkB in neuronal amphisomes is involved in plas
Externí odkaz:
https://doaj.org/article/8405b7ea05e8461086f8fdd56ee7dec8
Publikováno v:
Journal of Orthopedics, Traumatology and Rehabilitation, Vol 10, Iss 2, Pp 131-136 (2018)
Context: Enlargement of osseous tunnels following anterior cruciate ligament (ACL) reconstruction is a newer discovery. This phenomenon is particularly valuable in planning for revision ACL reconstruction. Aim: The purpose of this study was to evalua
Externí odkaz:
https://doaj.org/article/478c6cf30a1747e59beb8387c0f77b75
Autor:
Rajeev Raman, V Rajanikanth, Raghavan U M Palaniappan, Yi-Pin Lin, Hongxuan He, Sean P McDonough, Yogendra Sharma, Yung-Fu Chang
Publikováno v:
PLoS ONE, Vol 5, Iss 12, p e14377 (2010)
BackgroundMany bacterial surface exposed proteins mediate the host-pathogen interaction more effectively in the presence of Ca²+. Leptospiral immunoglobulin-like (Lig) proteins, LigA and LigB, are surface exposed proteins containing Bacterial immuno
Externí odkaz:
https://doaj.org/article/5f2894d46a5b409ca0e3a74648b3ad6a
Publikováno v:
Arthroscopy Techniques. 11:e2347-e2355
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::16d8d1e7f8696b382edd3328168caaea
https://doi.org/10.1016/j.eats.2022.08.041
https://doi.org/10.1016/j.eats.2022.08.041
Publikováno v:
International Journal of Neural Systems. 33
Deep learning has become a primary choice in medical image analysis due to its powerful representation capability. However, most existing deep learning models designed for medical image classification can only perform well on a specific disease. The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::44af3b691e4c27be5d3b5eb15d6f4551
https://doi.org/10.1142/s0129065723500107
https://doi.org/10.1142/s0129065723500107
Autor:
Katarzyna M Grochowska, Guilherme M Gomes, Rajeev Raman, Rahul Kaushik, Liudmila Sosulina, Hiroshi Kaneko, Anja M Oelschlegel, PingAn Yuanxiang, Irene Reyes‐Resina, Gonca Bayraktar, Sebastian Samer, Christina Spilker, Marcel S Woo, Markus Morawski, Jürgen Goldschmidt, Manuel A Friese, Steffen Rossner, Gemma Navarro, Stefan Remy, Carsten Reissner, Anna Karpova, Michael R Kreutz
Publikováno v:
The EMBO journal, 42(4):e112453
The EMBO journal 42(4), e112453 (2023). doi:10.15252/embj.2022112453
The EMBO journal 42(4), e112453 (2023). doi:10.15252/embj.2022112453
Synaptic dysfunction caused by soluble β-amyloid peptide (Aβ) is a hallmark of early-stage Alzheimer's disease (AD), and is tightly linked to cognitive decline. By yet unknown mechanisms, Aβ suppresses the transcriptional activity of cAMP-responsi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10b4e66e4bdf94453ba2c55d601ee9d1
https://www.embopress.org/doi/full/10.15252/embj.2022112453#support-information-section
https://www.embopress.org/doi/full/10.15252/embj.2022112453#support-information-section
Autor:
Marvin Löbel, Gonzalo Navarro, Rodrigo Cánovas, Johannes Fischer, Diego Arroyuelo, Rajeev Raman, Dominik Köppl
Publikováno v:
ACM Journal of Experimental Algorithmics. 26:1-47
The Lempel-Ziv 78 ( LZ78 ) and Lempel-Ziv-Welch ( LZW ) text factorizations are popular, not only for bare compression but also for building compressed data structures on top of them. Their regular factor structure makes them computable within space
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f9e00b379f4386fbb4a880d9c0c32129
https://doi.org/10.1145/3481638
https://doi.org/10.1145/3481638