Zobrazeno 1 - 10
of 17
pro vyhledávání: '"RAJAMANIKKAM, Kamaraj"'
Autor:
Anna Durinova, Lucie Smutna, Pavel Barta, Rajamanikkam Kamaraj, Tomas Smutny, Bernhard Schmierer, Petr Pavek, Frantisek Trejtnar
Publikováno v:
EJNMMI Radiopharmacy and Chemistry, Vol 9, Iss 1, Pp 1-16 (2024)
Abstract Background Megalin (LRP2 receptor) mediates the endocytosis of radiolabeled peptides into proximal tubular kidney cells, which may cause nephrotoxicity due to the accumulation of a radioactive tracer. The study aimed to develop a cellular mo
Externí odkaz:
https://doaj.org/article/597d143506c24767ad940c67ab4c86df
Publikováno v:
Cells, Vol 11, Iss 19, p 2974 (2022)
The pregnane X receptor (PXR, NR1I2) is a xenobiotic-activated transcription factor with high levels of expression in the liver. It not only plays a key role in drug metabolism and elimination, but also promotes tumor growth, drug resistance, and met
Externí odkaz:
https://doaj.org/article/de607d68ad2e43dbb50e089162525b94
Autor:
Pavel Barta, Rajamanikkam Kamaraj, Monika Kucharova, Zbynek Novy, Milos Petrik, Katerina Bendova, Marian Hajduch, Petr Pavek, Frantisek Trejtnar
Publikováno v:
Bioconjugate Chemistry. 33:1825-1836
Autor:
Pavel, Barta, Rajamanikkam, Kamaraj, Monika, Kucharova, Zbynek, Novy, Milos, Petrik, Katerina, Bendova, Marian, Hajduch, Petr, Pavek, Frantisek, Trejtnar
Publikováno v:
Bioconjugate chemistry. 33(10)
As angiogenesis plays a key role in tumor growth and metastasis, the angiogenic process has attracted scientific interest as a target for diagnostic and therapeutic agents. Factors influencing angiogenesis include the vascular endothelial growth fact
Publikováno v:
Critical Reviews in Food Science & Nutrition; 2023, Vol. 63 Issue 19, p3279-3301, 23p
Autor:
Petr, Pavek, Jan, Dusek, Tomas, Smutny, Lukas, Lochman, Radim, Kucera, Josef, Skoda, Lucie, Smutna, Rajamanikkam, Kamaraj, Pavel, Soucek, Radim, Vrzal, Zdenek, Dvorak
Publikováno v:
Molecular nutritionfood research. 66(9)
CYP3A4 is the most important drug-metabolizing enzyme regulated via the vitamin D receptor (VDR) in the intestine. However, less is known about VDR in the regulation of CYP3A4 and other drug-metabolizing enzymes in the liver.This study investigates w
Autor:
Rajamanikkam Kamaraj
Publikováno v:
International Journal of Innovative Technology and Exploring Engineering. 9:677-682
Amputated earthworm, Eudrilus eugeniae, possessing clitellum region has regenerating ability and develop into complete worms. Earthworm regeneration assay was developed based on this phenomenon and utilized to identify the presence of antimitotic com
Autor:
Rajamanikkam Kamaraj
Publikováno v:
International Journal of Engineering and Advanced Technology. 9:792-796
Knowledge on interactions between earthworms and microbes at molecular level has been obscure. Mechanism by which earthworms defend themselves against different microorganisms in the soil is largely unknown. Coelomic fluid from earthworm species has
Autor:
RAJAMANIKKAM, Kamaraj1, ELAIYA RAJA, Subramanian2, BALAJI, Senthamarai Kannan1, NADANA RAJAVADIVU, Ganapathy1, SIVASUBRAMANIAM, Sudhakar2, PALANICHELVAM, Karuppaiah1 palanichelvam@klu.ac.in
Publikováno v:
Turkish Journal of Zoology. 2019, Vol. 43 Issue 2, p153-163. 11p.
Publikováno v:
Critical reviews in food science and nutrition.
As a promiscuous xenobiotic sensor, pregnane X receptor (PXR) plays a crucial role in drug metabolism. Since dietary phytochemicals exhibit the potential to modulate human PXR, this review aims to summarize the plant-derived PXR modulators, including