Increased Stiffness Downregulates Focal Adhesion Kinase Expression in Pancreatic Cancer Cells Cultured in 3D Self-Assembling Peptide Scaffolds

Autor: Nausika Betriu, Anna Andreeva, Anna Alonso, Carlos E. Semino

Publikováno v: Biomedicines, Vol 10, Iss 8, p 1835 (2022)

The focal adhesion kinase (FAK) is a non-receptor tyrosine kinase that participates in integrin-mediated signal transduction and contributes to different biological processes, such as cell migration, survival, proliferation and angiogenesis. Moreover

Externí odkaz: https://doaj.org/article/1912c9bc45774f3ea5cbe6447fb4e167

Development of a Three-Dimensional Bioengineered Platform for Articular Cartilage Regeneration

Autor: Gerard Rubí-Sans, Lourdes Recha-Sancho, Soledad Pérez-Amodio, Miguel Ángel Mateos-Timoneda, Carlos Eduardo Semino, Elisabeth Engel

Publikováno v: Biomolecules, Vol 10, Iss 1, p 52 (2019)

Degenerative cartilage pathologies are nowadays a major problem for the world population. Factors such as age, genetics or obesity can predispose people to suffer from articular cartilage degeneration, which involves severe pain, loss of mobility and

Externí odkaz: https://doaj.org/article/2a7784c3104744179a291159b17447b9

Development of a 3D Co-Culture System as a Cancer Model Using a Self-Assembling Peptide Scaffold

Autor: Nausika Betriu, Carlos E. Semino

Publikováno v: Gels, Vol 4, Iss 3, p 65 (2018)

Cancer research has traditionally relied on two-dimensional (2D) cell culture, focusing mainly on cancer cells and their abnormal genetics. However, over the past decade, tumors have been accepted as complex tissues rather than a homogenous mass of p

Externí odkaz: https://doaj.org/article/c3d2ac5f9ca04e06bef8540686849528

Development of a Three-Dimensional Bioengineered Platform for Articular Cartilage Regeneration

Autor: Lourdes Recha-Sancho, Soledad Pérez-Amodio, Miguel A. Mateos-Timoneda, Gerard Rubí-Sans, Carlos E. Semino, Elisabeth Engel

Publikováno v: Biomolecules, Vol 10, Iss 1, p 52 (2019)
Biomolecules
Volume 10
Issue 1
UPCommons. Portal del coneixement obert de la UPC
Universitat Politècnica de Catalunya (UPC)

Degenerative cartilage pathologies are nowadays a major problem for the world population. Factors such as age, genetics or obesity can predispose people to suffer from articular cartilage degeneration, which involves severe pain, loss of mobility and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::813275ade99b599080f9a35d124d7639
https://www.mdpi.com/2218-273X/10/1/52

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