Výsledky vyhledávání - "RACHEL E. DILLARD"

1346-P: Obesity and Type 2 Diabetes in Patients with NAFLD Are Independently Associated with the Risk of Liver Fibrosis, Insulin Resistance, and Atherogenic Dyslipidemia

Autor: APRIL MATHEWS, SRILAXMI KALAVALAPALLI, EDDISON GODINEZ, ROMINA LOMONACO, RACHEL E. DILLARD, MARIA A. GONZALEZ, STEPHEN A. MARANGI, SHWETHA S. SHETTY, SULAV SHRESTHA, LYDIA MANSOUR, MARGERY A. CONNELLY, KELLY Y. CHUN, DIANA BARB, KENNETH CUSI

Publikováno v: Diabetes. 71

Obesity (OB) and type 2 diabetes (T2D) are associated with NAFLD and a worse cardiometabolic profile. However, their independent contribution to steatosis, fibrosis, insulin resistance (IR) and atherogenic dyslipidemia are controversial. To this end,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::cbc5631dd704491a74cc8541cd4b6e69
https://doi.org/10.2337/db22-1346-p

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283-OR: Inadequate Hepatic Mitochondrial Adaptation in Patients with NASH Is Related to the Severity of Steatohepatitis and Fibrosis Stage

Autor: Diana Barb, Jeffrey Friedman, Tyler M. Cowan, Fernando Bril, Kenneth Cusi, Sushma Kadiyala, Sulav Shrestha, Sreevidya Subbarayan, Rachel E. Dillard, Lydia Mansour, Srilaxmi Kalavalapalli, Nada Fanous, Eddison Godinez, Stephanie E. Wohlgemuth, Danielle Poulton, Romina Lomonaco

Publikováno v: Diabetes. 70

Dysfunctional mitochondrial function plays an important role in the progression of nonalcoholic steatohepatitis (NASH). Mitochondrial (mt) respiratory function assessed by oxidative phosphorylation/ OXPHOS (activated respiration with mt complex I [OX

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3bc8f42c1b165029711f56e1e3350852
https://doi.org/10.2337/db21-283-or

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Severe Disease Activity and Liver Fibrosis Are Associated With a Lack of Hepatic Mitochondrial Adaptation in Patients With NASH

Autor: Srilaxmi Kalavalapalli, Sulav Shrestha, Diana Barb, Nada Fanous, Eddison Godinez Leiva, Lydia Mansour, Matthew Rabe, Rachel E. Dillard, Radhika Chug, Danielle Poulton, Romina Lomonaco, Jeffrey Friedman, Tyler M. Cowan, Kenneth Cusi

Publikováno v: Journal of the Endocrine Society

Dysfunctional mitochondrial function is believed to play a vital role in the progression of nonalcoholic steatohepatitis (NASH) to advanced fibrosis and cirrhosis. However, most evidence arises from animal models while there is limited data in humans

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed081cfba4ee2bd6afb258f981f51f69
https://doi.org/10.1210/jendso/bvab048.053

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