Zobrazeno 1 - 10
of 30
pro vyhledávání: '"RAA System and Endocrine Hypertension"'
Autor:
Andrea Vecchiola, Cristian A. Carvajal, Carmen Campino, Alejandra Tapia, Carlos Salomon, Carlos E. Fardella, Rene Baudrand, Eric Barros, Fidel Allende
Publikováno v:
Journal of the Endocrine Society
Mineralocorticoid arterial hypertension has risen as one of the most prevalent causes of secondary hypertension, where 11β-hydroxysteroid dehydrogenase type-2 partial deficiency (also known as non-classical AME (NC-AME)), could reach a prevalence of
Autor:
Mika Tsuiki, Toshihiko Yanase, Norio Wada, Hirotaka Shibata, Akiyo Tanabe, Takamasa Ichijo, Masakatsu Sone, Yoshihiro Ogawa, Isao Kurihara, Yoshiyu Takeda, Jpas, Mitsuhide Naruse, Takuyuki Katabami
Publikováno v:
Journal of the Endocrine Society
Background: Primary aldosteronism (PA) is a representative cause of endocrine hypertension characterized by an excess production of aldosterone, hypertension, and cardiovascular complications. Although clinical practice guidelines have been published
Autor:
Augusto G Guimaraes, Janaina Petenuci, Bruna Pilan, Luiz Aparecido Bortolotto, Jose Luis Chambo, Thaís Castanheira, Leticia A P Vilela, André Sanches de Abreu, Berenice B. Mendonca, Marcela Rassi-Cruz, Francisco Cesar Carnevale, Fabio Y Tanno, Maria Candida Barisson Villares Fragoso, Caio Santiago Moises, Madson Q. Almeida, Vitor Srougi, Maria Adelaide Albergaria Pereira, Maria Claudia Nogueira Zerbini, Fernando Ide Yamauchi, Ana Claudia Latronico, Luciano F. Drager, Natalia Alencar, Giovanio Vieira da Silva, Aline C B S Cavalcante
Publikováno v:
Journal of the Endocrine Society
Primary aldosteronism (PA) is the most common cause of endocrine hypertension. The 2016 Endocrine Society’s Guideline for PA management recommend that patients with a positive screening undergo one or more confirmatory tests to definitively confirm
Autor:
Arshag D. Mooradian, Priyanka Bikkina, Michael J. Haas, Shrina Parekh, Poonam Kalidas, Marie Angelica Landicho
Publikováno v:
Journal of the Endocrine Society
Background. GLP1R agonists and SGLT2 inhibitors are classes of medications used in diabetes management. They possess antioxidative properties and inhibit the unfolded protein response (UPR) (endoplasmic reticulum (ER) stress). Since the UPR is involv
Autor:
Jimmy Shen, Peter J. Fuller, Stella May Gwini, Amrina Kaur, Om Narayan, Jun Yang, Morag J. Young, Serena Menezes
Publikováno v:
Journal of the Endocrine Society
Background: Primary aldosteronism (PA) has a reported prevalence of up to 30% in cases of resistant hypertension and is associated with worse cardiovascular outcomes than BP-matched essential hypertension (EH), but is substantially under-diagnosed du
Autor:
James R. Sowers, Yan Yang, Michael A. Hill, Guido Lastra, Frederic Jaisser, Guanghong Jia, Adam Whaley-Connell, Annayya R. Aroor, Javad Habibi
Publikováno v:
Journal of the Endocrine Society
Excessive epithelial sodium channel activation in endothelium (EnNaC) increase oxidative stress and inflammation with associated cardiovascular abnormalities. Our recent data has shown that activation of EnNaC mediates aortic endoplasmic reticulum st
Autor:
Latha M. Malaiyandi, Harsh Sharthiya, Kirk E. Dineley, Nuntida Surachaicharn, Philip Kopf, Annette Gilchrist
Publikováno v:
Journal of the Endocrine Society
Intracellular calcium fluctuations may play a role in the control of corticosteroid synthesis and secretion by the adrenal cortex. Using live-cell imaging with the calcium-sensitive fluorescent probe Fluo-4 in a human adrenocortical carcinoma cell li
Autor:
Lakshmi Das, Shiri Levy-Basso
Publikováno v:
Journal of the Endocrine Society
Primary aldosteronism is an underdiagnosed cause of hypertension. Classically, primary hyperaldosteronism presents with hypertension and hypokalemia, although hypokalemia is not necessary to diagnose this condition. We present here a curious case of
Autor:
Hiroko Ogata, Kensuke Joh, Fumitoshi Satoh, Yoichi Arai, Sadayoshi Ito, Hironobu Sasano, Yoshikiyo Ono, Kei Omata, Yuta Tezuka, Hiroshi Sato, Yuto Yamazaki, Mariko Miyazaki, Yasuhiro Nakamura, Ryo Morimoto
Publikováno v:
Journal of the Endocrine Society
Primary aldosteronism (PA) is a major cause of secondary hypertension, accounting for 5 to 10% of all of the patients with hypertension. PA is also well known to harbor relatively higher incidence of cardiovascular complications than essential hypert
Autor:
Andrea Vecchiola
Publikováno v:
Journal of the Endocrine Society
Background: Aldosterone has been linked with obesity, metabolic syndrome (MetS), pro-inflammatory and pro-thrombotic states. However, most of these studies relate to patients with evident primary aldosteronism (PA). Objective: To determine whether al