Zobrazeno 1 - 10
of 56
pro vyhledávání: '"RA1190"'
Autor:
Wendy Masterton, Danilo Falzon, Gillian Burton, Hannah Carver, Bruce Wallace, Elizabeth V. Aston, Harry Sumnall, Fiona Measham, Rosalind Gittins, Vicki Craik, Joe Schofield, Simon Little, Tessa Parkes
Publikováno v:
International journal of environmental research and public health. 19(19)
With rising numbers of drug-related deaths in the UK and globally, exploration of interventions that seek to reduce drug-related harm is essential. Drug checking services (DCS) allow people to submit drug samples for chemical analysis and receive fee
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39094b04fa7845f02545d368651cd394
https://pubmed.ncbi.nlm.nih.gov/36231262
https://pubmed.ncbi.nlm.nih.gov/36231262
Autor:
James Nicholls, Wulf Livingston, Andy Perkins, Beth Cairns, Rebecca Foster, Kirsten M. A. Trayner, Harry R. Sumnall, Tracey Price, Paul Cairney, Josh Dumbrell, Tessa Parkes
Publikováno v:
International Journal of Environmental Research and Public Health; Volume 19; Issue 11; Pages: 6575
There is widespread support for the introduction of Drug Consumption Rooms (DCRs) in Scotland as part of a policy response to record levels of drug-related harm. However, existing legal barriers are made more complex by the division of relevant power
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40ff2d2f3e8a45764e117dc31b5dd5a2
Autor:
Martyn L. Chilton, Anne Marie Api, Robert S. Foster, G. Frank Gerberick, Maura Lavelle, Donna S. Macmillan, Mihwa Na, Devin O'Brien, Catherine O'Leary-Steele, Mukesh Patel, David J. Ponting, David W. Roberts, Robert J. Safford, Rachael E. Tennant
Publikováno v:
Regulatory toxicology and pharmacology : RTP. 133
The Dermal Sensitisation Thresholds (DST) are Thresholds of Toxicological Concern, which can be used to justify exposure-based waiving when conducting a skin sensitisation risk assessment. This study aimed to update the published DST values by expand
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d750de7d1a7ff504f5fa7748836ba6e3
https://pubmed.ncbi.nlm.nih.gov/35662638
https://pubmed.ncbi.nlm.nih.gov/35662638
Publikováno v:
International Journal of Environmental Research and Public Health; Volume 19; Issue 13; Pages: 7828
(1) Background: The popularity of electronic cigarettes (e-cigarettes) has recently increased. Although they are less harmful than regular cigarettes, they still cause health consequences and their use for smoking cessation is inconclusive. The objec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d26f1a391fbd60ce616c01d0b904ac0
https://pubmed.ncbi.nlm.nih.gov/35805487
https://pubmed.ncbi.nlm.nih.gov/35805487
Publikováno v:
Archives of Toxicology
The quantitative adverse outcome pathway (qAOP) concept is gaining interest due to its potential regulatory applications in chemical risk assessment. Even though an increasing number of qAOP models are being proposed as computational predictive tools
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0aa89d0a6231dbca85b358858f2533a6
http://europepmc.org/articles/PMC7261727
http://europepmc.org/articles/PMC7261727
Autor:
Sian Nelder, Fahima Ismail, Iain P. Hargreaves, Sioned Roberts, Sue Phillips, Nadia Turton, Robert A Heaton
Publikováno v:
Neurochemical Research
Organophosphate (OP) compounds are widely used as pesticides and herbicides and exposure to these compounds has been associated with both chronic and acute forms of neurological dysfunction including cognitive impairment, neurophysiological problems
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c1388a355227d01f42bd4ccda277cc1
http://europepmc.org/articles/PMC7829235
http://europepmc.org/articles/PMC7829235
Autor:
Jason W. Birkett, Amelia Taylor
Publikováno v:
Drug Testing and Analysis. 12:180-190
A review of the literature surrounding the use, analysis, and detection of pesticide material for cannabis cultivation is presented. The use of pesticides in crop cultivation is not new, and cannabis crops are no exception. Studies have found that th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac8c735ee5e136f348987d47074ec524
https://doi.org/10.1002/dta.2747
https://doi.org/10.1002/dta.2747
Autor:
Thomas Exner, Mirjam Luijten, Julia Pletz, M.E. Bette Meek, Johannes W. Kruisselbrink, Mark T. D. Cronin, Alicia Paini, Caroline Gomes, David Asturiol, Clemens Wittwehr, Andreas Schüttler, Andrew Worth, Wang Gao, Daniel L. Villeneuve, Ivana Campia, Nicoleta Spinu, Marvin Martens, Stefan Scholz, David Pamies, Lidia Ceriani
Publikováno v:
Computational Toxicology, 21:100195. Elsevier BV
Computational Toxicology
Computational Toxicology, 2021, pp.100195. ⟨10.1016/j.comtox.2021.100195⟩
Computational Toxicology, 21
Computational Toxicology 21 (2022)
Computational Toxicology
Computational Toxicology, 2021, pp.100195. ⟨10.1016/j.comtox.2021.100195⟩
Computational Toxicology, 21
Computational Toxicology 21 (2022)
International audience; The adverse outcome pathway (AOP) is a conceptual construct that facilitates organisation and interpretation of mechanistic data representing multiple biological levels and deriving from a range of methodological approaches in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::286bd34c19b0b3674e1eccdeb370c89e
https://cris.maastrichtuniversity.nl/en/publications/fc1078fe-bf3c-44a7-8d22-55b77805b0ff
https://cris.maastrichtuniversity.nl/en/publications/fc1078fe-bf3c-44a7-8d22-55b77805b0ff
Autor:
Jean-Pierre Valentin, Daniel P. Russo, David T. Szabo, Lidiya Stavitskaya, Patricia Ruiz, Craig Zwickl, Louise Neilson, Vinicius M. Alves, Candice Johnson, Andreas Bender, Arianna Bassan, Lennart T. Anger, Reena Sandhu, David Woolley, Lisa Beilke, Manuela Pavan, Raymond Kemper, Mark T. D. Cronin, Moiz Mumtaz, Glenn J. Myatt, Alexander Amberg, Yogesh Sabnis, Jui-Hua Hsieh, Markus Schaefer, Amy Pointon, Autumn Bernal, Julia Pletz
Publikováno v:
Comput Toxicol
The kidneys, heart and lungs are vital organ systems evaluated as part of acute or chronic toxicity assessments. New methodologies are being developed to predict these adverse effects based on in vitro and in silico approaches. This paper reviews the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e41082bb951a3c41285999b6f292588
https://europepmc.org/articles/PMC9205464/
https://europepmc.org/articles/PMC9205464/
Autor:
Mark T.D. Cronin, Franklin J. Bauer, Mark Bonnell, Bruno Campos, David J. Ebbrell, James W. Firman, Steve Gutsell, Geoff Hodges, Grace Patlewicz, Maria Sapounidou, Nicoleta Spînu, Paul C. Thomas, Andrew P. Worth
Publikováno v:
Regulatory Toxicology and Pharmacology. 135:105249
Structure-activity relationships (SARs) in toxicology have enabled the formation of structural rules which, when coded as structural alerts, are an essential tool in in silico toxicology. Whilst other in silico methods have approaches for their evalu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa2c754db0a3692430e9a43d0a7f965f
https://doi.org/10.1016/j.yrtph.2022.105249
https://doi.org/10.1016/j.yrtph.2022.105249