Zobrazeno 1 - 10
of 72
pro vyhledávání: '"RA, retinoic acid"'
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 11, Iss 2, Pp 309-321 (2021)
Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica. B
Cullin-RING ligases (CRLs) recognize and interact with substrates for ubiquitination and degradation, and can be targeted for disease treatment when the abnormal expression of substrates involves pathologic processes. Phosphorylation, either of subst
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f27b7f488f3a53677836e1b8e5b2722d
https://doi.org/10.1016/j.apsb.2020.09.007
https://doi.org/10.1016/j.apsb.2020.09.007
Autor:
Gemma Navarro, Alvaro Lladser, Javier Campos, Alexandra Espinoza, Francisco Contreras, Carolina Prado, Iu Raïch, Rodrigo Pacheco, Rafael Franco, Francisco Osorio-Barrios, Ernesto Lopez, Valentina Ugalde
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 12, Iss 2, Pp 489-506 (2021)
Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology
Background and aims: CD4+ T cells constitute central players in inflammatory bowel diseases (IBDs), driving inflammation in the gut mucosa. Current evidence indicates that CCR9 and the integrin α4β7 are necessary and sufficient to imprint colonic h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17853d8965fd2dd62836241f51298962
http://www.sciencedirect.com/science/article/pii/S2352345X21000771
http://www.sciencedirect.com/science/article/pii/S2352345X21000771
Publikováno v:
The Journal of Biological Chemistry
Previous studies suggested that cancer cells resemble neural stem/progenitor cells in regulatory network, tumorigenicity, and differentiation potential, and that neural stemness might represent the ground or basal state of differentiation and tumorig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aca3a029c734925ba928159d89929a50
http://europepmc.org/articles/PMC8546425
http://europepmc.org/articles/PMC8546425
Autor:
Kenji Kamimoto, Samantha A. Morris, Brad W. Warner, Cathleen M. Courtney, Wenjun Kong, William H. Goo, Sarah E. Waye, Kristen M. Seiler, Adam Bajinting, Jun Guo, Emily J. Onufer
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology, Vol 8, Iss 3, Pp 407-426 (2019)
Cellular and Molecular Gastroenterology and Hepatology, Vol 8, Iss 3, Pp 407-426 (2019)
Background & Aims The small intestine (SI) displays regionality in nutrient and immunological function. Following SI tissue loss (as occurs in short gut syndrome, or SGS), remaining SI must compensate, or “adapt”; the capacity of SI epithelium to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee63d6c1e370ac6859fe49b3aee2f738
http://europepmc.org/articles/PMC6718927
http://europepmc.org/articles/PMC6718927
Publikováno v:
Pharmacology & Therapeutics
Individuals differ substantially in their response to pharmacological treatment. Personalized medicine aspires to embrace these inter-individual differences and customize therapy by taking a wealth of patient-specific data into account. Pharmacogenom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c77b497b32c4399ec51c1cb33968c9c
https://doi.org/10.1016/j.pharmthera.2019.01.002
https://doi.org/10.1016/j.pharmthera.2019.01.002
Publikováno v:
Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica B, Vol 9, Iss 2, Pp 220-236 (2019)
Acta Pharmaceutica Sinica B, Vol 9, Iss 2, Pp 220-236 (2019)
Obesity is increasing in an alarming rate worldwide, which causes higher risks of some diseases, such as type 2 diabetes, cardiovascular diseases, and cancer. Current therapeutic approaches, either pancreatic lipase inhibitors or appetite suppressors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ee24ee4e685885a371ae80f1d618f98
https://doi.org/10.1016/j.apsb.2018.09.007
https://doi.org/10.1016/j.apsb.2018.09.007
Autor:
Charles Nicaise, Kevin Willemart, Florian Poulain, Nicolas Gillet, Noémie Avalosse, Riselane Lotfi, Jacques Gilloteaux, Noelle Ninanne, Noémie Lejeune, Kathleen De Swert, Valery Bielarz
Publikováno v:
Brain Research
Bielarz, V, WILLEMART, KEVIN, Avalosse, N, De Swert, K, Lotfi, R, Lejeune, N, Poulain, F, Ninanne, N, GILLOTEAUX, J, GILLET, NICOLAS & Nicaise, C 2021, ' Susceptibility of neuroblastoma and glioblastoma cell lines to SARS-CoV-2 infection ', Brain research, vol. 1758, 147344 . https://doi.org/10.1016/j.brainres.2021.147344
Bielarz, V, WILLEMART, KEVIN, Avalosse, N, De Swert, K, Lotfi, R, Lejeune, N, Poulain, F, Ninanne, N, GILLOTEAUX, J, GILLET, NICOLAS & Nicaise, C 2021, ' Susceptibility of neuroblastoma and glioblastoma cell lines to SARS-CoV-2 infection ', Brain research, vol. 1758, 147344 . https://doi.org/10.1016/j.brainres.2021.147344
Modelling cell infection in-a-dish can represent a useful tool to understand the susceptibility of different cell types towards severe acute respiratory coronavirus-2 (SARS-CoV-2) and to decipher its neurotropism. In this perspective, retinoic acid (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd6b19eec2e5f936a29312b7975f27ca
https://researchportal.unamur.be/en/publications/b4334368-1063-4325-9db9-a5dc776e2c12
https://researchportal.unamur.be/en/publications/b4334368-1063-4325-9db9-a5dc776e2c12
Autor:
Lauren A. Hauser, Marek Napierala, Amanda Clark, Jennifer M. Farmer, Kimal Rajapakshe, David A. Lynch, Peining Xu, Clementina Mesaros, Dean P. Edwards, Yu-Yun Chen, Ian A. Blair, Shixia Huang, Cristian Coarfa, Jill S. Napierala
Publikováno v:
Molecular & Cellular Proteomics : MCP
Identifying biomarkers is important for assessment of disease progression, prediction of symptom development, and determination of treatment effectiveness. While unbiased analyses of differential gene expression using next-generation sequencing metho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::239d5431dbcbfd7df7c1a470624aee8d
http://europepmc.org/articles/PMC8214145
http://europepmc.org/articles/PMC8214145
Autor:
Murat Kizil, Muhammad Akram, Ahmet Çağkan İnkaya, Aziz Rodan Sarohan, Shokhan Mahmud, Osman Cen
Publikováno v:
Cellular Signalling
PMID: 34438017 WOS:000702705800007 The SARS-CoV-2 virus has caused a worldwide COVID-19 pandemic. In less than a year and a half, more than 200 million people have been infected and more than four million have died. Despite some improvement in the tr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97d922a6e000cd5762d69dbc32d1076f
https://pubmed.ncbi.nlm.nih.gov/34438017
https://pubmed.ncbi.nlm.nih.gov/34438017
Autor:
Olga V. Belyaeva, Wojciech Krezel, Kelli R. Goggans, Kirill M. Popov, Natalia Y. Kedishvili, Alla Klyuyeva
Publikováno v:
Journal of Biological Chemistry
Journal of Biological Chemistry, 2021, 296, ⟨10.1016/j.jbc.2021.100323⟩
The Journal of Biological Chemistry
Journal of Biological Chemistry, 2021, 296, ⟨10.1016/j.jbc.2021.100323⟩
The Journal of Biological Chemistry
Liver is the central metabolic hub that coordinates carbohydrate and lipid metabolism. The bioactive derivative of vitamin A, retinoic acid (RA), was shown to regulate major metabolic genes including phosphoenolpyruvate carboxykinase, fatty acid synt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::482164d931d63e8619988426a47c4614
https://hal.science/hal-03708081
https://hal.science/hal-03708081
